array:23 [ "pii" => "S0210480607736689" "issn" => "02104806" "doi" => "10.1016/S0210-4806(07)73668-9" "estado" => "S300" "fechaPublicacion" => "2007-01-01" "aid" => "73668" "copyright" => "Asociación Española de Urología (AEU)" "copyrightAnyo" => "2007" "documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Actas Urol Esp. 2007;31:452-68" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1555 "formatos" => array:3 [ "EPUB" => 9 "HTML" => 927 "PDF" => 619 ] ] "itemSiguiente" => array:18 [ "pii" => "S0210480607736690" "issn" => "02104806" "doi" => "10.1016/S0210-4806(07)73669-0" "estado" => "S300" "fechaPublicacion" => "2007-01-01" "aid" => "73669" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Actas Urol Esp. 2007;31:469-76" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1377 "formatos" => array:3 [ "EPUB" => 7 "HTML" => 869 "PDF" => 501 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Análisis estadístico de la influencia del virus del papiloma humano en el desarrollo del carcinoma vesical" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "469" "paginaFinal" => "476" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Statistical analysis of the influence of the virus of papiloma human in the development of the vesical carcinoma" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Jiménez Pacheco, J.L. Martínez Torres, M. Pareja Vilchez, M. Arrabal Martín, F. Valle Díaz de la Guardia, V. López León, A. Zuluaga Gómez" "autores" => array:7 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Jiménez Pacheco" ] 1 => array:2 [ "nombre" => "J.L." "apellidos" => "Martínez Torres" ] 2 => array:2 [ "nombre" => "M." "apellidos" => "Pareja Vilchez" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Arrabal Martín" ] 4 => array:2 [ "nombre" => "F." "apellidos" => "Valle Díaz de la Guardia" ] 5 => array:2 [ "nombre" => "V." "apellidos" => "López León" ] 6 => array:2 [ "nombre" => "A." "apellidos" => "Zuluaga Gómez" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480607736690?idApp=UINPBA00004N" "url" => "/02104806/0000003100000005/v1_201304251840/S0210480607736690/v1_201304251840/es/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S0210480607736677" "issn" => "02104806" "doi" => "10.1016/S0210-4806(07)73667-7" "estado" => "S300" "fechaPublicacion" => "2007-01-01" "aid" => "73667" "copyright" => "Asociación Española de Urología (AEU)" "documento" => "article" "crossmark" => 0 "subdocumento" => "rev" "cita" => "Actas Urol Esp. 2007;31:445-51" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1574 "formatos" => array:3 [ "EPUB" => 9 "HTML" => 978 "PDF" => 587 ] ] "es" => array:10 [ "idiomaDefecto" => true "titulo" => "Tratamiento actual del cáncer de próstata de alto riesgo y localmente avanzado" "tienePdf" => "es" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "445" "paginaFinal" => "451" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Current treatment in high risk and locally advanced prostate cancer" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "S. Esquena Fernández, P. Maroto Rey, G. Sancho Pardo, J. Palou Redorta, H. Villavicencio Mavrich" "autores" => array:5 [ 0 => array:2 [ "nombre" => "S." "apellidos" => "Esquena Fernández" ] 1 => array:2 [ "nombre" => "P." "apellidos" => "Maroto Rey" ] 2 => array:2 [ "nombre" => "G." "apellidos" => "Sancho Pardo" ] 3 => array:2 [ "nombre" => "J." "apellidos" => "Palou Redorta" ] 4 => array:2 [ "nombre" => "H." "apellidos" => "Villavicencio Mavrich" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0210480607736677?idApp=UINPBA00004N" "url" => "/02104806/0000003100000005/v1_201304251840/S0210480607736677/v1_201304251840/es/main.assets" ] "es" => array:14 [ "idiomaDefecto" => true "titulo" => "Braquiterapia de baja tasa en el tratamiento del cáncer de próstata localizado" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "452" "paginaFinal" => "468" ] ] "autores" => array:2 [ 0 => array:3 [ "autoresLista" => "A. Tormo Micó, A. Francés" "autores" => array:2 [ 0 => array:3 [ "nombre" => "A." "apellidos" => "Tormo Micó" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "A." "apellidos" => "Francés" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:1 [ 0 => array:3 [ "entidad" => "Servicios de Urología y Oncología Radioterápica" "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "aff0005" ] ] ] 1 => array:4 [ "autoresLista" => "A. Budía Alba, M. Bosquet Sanz, F. Boronat Tormo, J.M. Alapont Alacreu, C.D. Vera Donoso, J.F. Jiménez Cruz" "autores" => array:6 [ 0 => array:4 [ "nombre" => "A." "apellidos" => "Budía Alba" "email" => array:1 [ 0 => "budia@pulso.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">1</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Bosquet Sanz" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Boronat Tormo" ] 3 => array:2 [ "nombre" => "J.M." "apellidos" => "Alapont Alacreu" ] 4 => array:2 [ "nombre" => "C.D." "apellidos" => "Vera Donoso" ] 5 => array:2 [ "nombre" => "J.F." "apellidos" => "Jiménez Cruz" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Hospital Universitario La Fe de Valencia." ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "1" "correspondencia" => "Correspondencia: Dr. A. Budía Alba Servicio de Urología. Hospital Universitario La Fe Avda. Campanar, 21. 46009 Valencia Tel.: 963 862 700 Ext 40686" ] ] ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Indications, results and techniques of permanent prostate brachitherapy for localized prostate cancer" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-02-01" "fechaAceptado" => "2007-04-01" "PalabrasClave" => array:2 [ "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec88254" "palabras" => array:2 [ 0 => "Braquiterapia prostática" 1 => "Cáncer de próstata" ] ] ] "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec88253" "palabras" => array:2 [ 0 => "Prostate brachytherapy" 1 => "Prostate cancer" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción y Objetivo</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">La braquiterapia prostática se ha consolidado en los últimos años como tratamiento de primera línea en pacientes seleccionados con cáncer de próstata localizado. Pretendemos realizar una actualización del tema.</p> <span class="elsevierStyleSectionTitle">Material y Métodos</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Revisión bibliográfica de las principales series publicadas analizando, indicaciones (selección de pacientes), las diferentes técnicas de implantación, los resultados oncológicos en función de grupos de riesgo y las complicaciones agudas y crónicas.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0012" class="elsevierStyleSimplePara elsevierViewall">La supervivencia libre de recaída bioquímica fue del 87-96% a 10 años en tumores de bajo riesgo y del 63-86% a 10 años en tumores de riesgo intermedio. Las principales complicaciones fueron la retención urinaria en el 3-24%, necesitando RTU de próstata en 0-8,7%, la incontinencia urinaria en el 0-6,7%, proctitis en 0- 15,5%, disfunción eréctil en 6,3-30%, úlceras/fístulas rectales en 0-5,4%.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La braquiterapia prostática constituye una alternativa terapéutica en el cáncer de próstata localizado de bajo riesgo y en pacientes seleccionados de riesgo intermedio, con escasas complicaciones y una aceptable tasa de control bioquímico.</p>" ] "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction and objective</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Prostate brachytherapy is a first-line therapeutic approach for localized prostate cancer in selected patients. We present our experience in brachytherapy and a thorough review of the literature.</p> <span class="elsevierStyleSectionTitle">Materials and Methods</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A review of the literature and evaluation of patient’s selection was done. Furthermore the implantation technique, oncological results according to the different risk groups and acute and chronic complications were also analyzed.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">The biochemical relapse-free 10 year survival rate was 87-96% in low risk tumours and 63-86% in intermediate risk tumours. A total of 3-24% underwent urinary retention that required TURP in 0-8,7%. Other complications were urinary incontinence in 0-6,7%, proctitis in 0-15,5%, erectile dysfunction in 6,3-30%, rectal ulcer/fistula in 0-5,4%.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Prostate brachytherapy is a safe and effective treatment in low and intermediate risk patients with prostate cancer.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Referencias" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:90 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Brachytherapy for carcinoma of the prostate: techniques, patient selection, and clinical outcomes" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.C. Blasko" 1 => "T. Mate" 2 => "J.E. Sylvester" 3 => "P.D. Grimm" 4 => "W. 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Braquiterapia de baja tasa en el tratamiento del cáncer de próstata localizado
Indications, results and techniques of permanent prostate brachitherapy for localized prostate cancer
* Servicios de Urología y Oncología Radioterápica
A. Budía Alba1
, M. Bosquet Sanz, F. Boronat Tormo, J.M. Alapont Alacreu, C.D. Vera Donoso, J.F. Jiménez Cruz
Autor para correspondencia
budia@pulso.com
Correspondencia: Dr. A. Budía Alba Servicio de Urología. Hospital Universitario La Fe Avda. Campanar, 21. 46009 Valencia Tel.: 963 862 700 Ext 40686
Correspondencia: Dr. A. Budía Alba Servicio de Urología. Hospital Universitario La Fe Avda. Campanar, 21. 46009 Valencia Tel.: 963 862 700 Ext 40686
Hospital Universitario La Fe de Valencia.
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Braquiterapia de baja tasa en el tratamiento del cáncer de próstata localizado
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