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Inicio Acta Otorrinolaringológica Española Análisis descriptivo y resultados quirúrgicos del hiperparatiroidismo primario
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Vol. 53. Issue 10.
Pages 773-780 (December 2002)
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Vol. 53. Issue 10.
Pages 773-780 (December 2002)
Análisis descriptivo y resultados quirúrgicos del hiperparatiroidismo primario
Descriptive Analysis And Surgical Outcome Of Primary Hyperparathyroidism
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M.J. Ferrer Ramírez*,1, M. Arroyo Domingo*, C. López Mollá*, A. Plá Mocholí*, A. Hernández Mijares**, R. López Martínez*
* Servicio de OtorrinolaringologÍa
** Servicio de EndocrinologÍa y NutriciÓn. Hospital Universitario Dr. Peset. Valencia
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Resumen

El hiperparatiroidismo primario (HPP) ha pasado de ser una enfermedad rara caracterizada por presentar una sintomatología florida renal y esquelética, a ser una enfermedad más común con mínima sintomatología. El empleo difundido de los autoanalizadores ha conducido a un aumento en su incidencia y a que el diagnóstico se realice precozmente. El objetivo de este estudio es analizar la forma de presentación y alteraciones bioquímicas, así como los hallazgos quirúrgicos y resultados postoperatorios de un grupo de pacientes diagnosticados de HPP e intervenidos quirúrgicamente. De los 71 pacientes estudiados, la mayoría presentaban sintomatología en el momento del diagnóstico, 6 eran asintomáticos y 11 normocalcémicos. En 5 pacientes fue necesaria una reintervención por HPP persistente. El 95,77% de los pacientes normalizaron los niveles de hormona paratiroidea tras la cirugía. La paratiroidectomía es una técnica segura y efectiva que debe ser indicada precozmente, incluso en los casos asintomáticos.

Palabras clave:
Hiperparatiroidismo primario
Paratiroidectomía
Hormona paratiroidea
Abstract

Primary hyperparathyroidism (PHPT) was a rare but serious disease with massive biochemical, renal and skeletal signs at the time of diagnosis. In the last decades it has become a more common disorder often diagnosed by chance. The disease usually shows minimal symptoms. These clinical changes are due to advances in biochemical screening procedures, which have led to a remarkable increase in the incidence of PHPT. The aim of this study is to describe the clinical profiles, biochemical data, operative findings and postoperative results. Seventy one consecutive patients were prospectively enrolled and underwent surgical examination. Most of them showed symptoms: 6 patients were asymptomatic and 11 had a normocalcemic hyperparathyroidism. After surgery 5 patients showed persistent primary hyperparathyroidism. Parathyroid hormone concentration returned to normal levels in 95.77% of the patients studied. Parathyroidectomy is a safe and effective approach to the treatment of primary hyperparathyroidism.

Key words:
Primary hyperparathyroidism
Parathyroidectomy
Parathyroid hormone

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