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Inicio Acta Otorrinolaringológica Española Diagnóstico del schwannoma intracraneal del nervio facial. factores clínicos, ...
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Vol. 55. Issue 9.
Pages 399-403 (October 2004)
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Vol. 55. Issue 9.
Pages 399-403 (October 2004)
Diagnóstico del schwannoma intracraneal del nervio facial. factores clínicos, radiológicos y valor de la inmunohistoquímica
Diagnosis of intracranial facial schwannoma: clinical, and radiological factors, and the value of immunohistochemistry
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L. Lassaletta1,a
Corresponding author
luislassaletta@wanadoo.es

Luis Lassaletta Atienza. Servicio de ORL. Hospital Universitario “La Paz”. Pº de la Castellana, 261. 28046 Madrid
, A. Castro1, M. Patrón2, M.J. Sarriá1, J. Gavilán1
1 Servicio de orl
2 Departamento de anatomía patológica. hospital universitario “la paz”. madrid
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Resumen
Objetivo

Analizar qué factores clínicos, radiológicos e inmunohistoquímicos pueden ser útiles para diferenciar los schwannomas vestibulares de los schwannomas intracraneales del nervio facial

Material y métodos

Presentamos un estudio retrospectivo de 91 pacientes operados con la sospecha clínica de schwannoma vestibular. Se analizaron factores clínicos y radiológicos. Se realizó una tinción inmunohistoquímica para neurofilamentos en casos seleccionados de schwannomas vestibulares unilaterales, schwannomas vestibulares bilaterales y schwannomas del nervio facial

Resultados

El 83% de los pacientes con schwannomas vestibulares tenían una función facial preoperatoria normal. Los dos pacientes con schwannomas del nervio facial tenían una función grado II de House-Brackmann. La RM no mostró diferencias entre los schwannomas vestibulares y faciales. La inmunohistoquímica fue positiva en los schwannomas vestibulares unilaterales, los schwannomas vestibulares bilaterales y los schwannomas del nervio facial

Conclusiones

No hay factores clínicos, radiológicos ni patológicos específicos para diferenciar los schwannomas vestibulares de los schwannomas del nervio facial

Palabras clave:
Schwannoma intracraneal del nervio facial
Schwannoma vestibular
Parálisis facial
Resonancia Magnética
Inmunohistoquímica
Abstract
Objective

To analyze the clinical, radiological, and pathological features which may be useful to differentiate intracranial schwannomas of the facial nerve from vestibular schwannomas

Material and Methods

A retrospective study of 91 patients undergoing surgery with a clinical suspicion of vestibular schwannoma is presented. Clinical and radiological features are analyzed. Immunohistochemistry for neurofilaments was performed in selected cases of unilateral vestibular schwannomas, bilateral vestibular schwannomas, and facial nerve schwannomas

Results

Facial function was normal in 83% of patients with vestibular schwannoma. Both patients with facial schwannomas had preoperative House-Brackmann grade II facial function. MRI showed no main differences between facial and vestibular schwannomas. A positive immunostaining was found in unilateral vestibular schwannomas, bilateral vestibular schwannomas, and facial nerve schwannomas

Conclusion

There are no specific clinical, radiological, or pathological factors to accurately differentiate schwannomas of the facial nerve from vestibular schwannomas

Key words:
Intracranial facial schwannoma
Vestibular schwannoma
Facial paralysis
Diagnosis
Magnetic Resonance
Immunohistochemistry

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