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Inicio Acta Otorrinolaringológica Española Diseño y realización de un laboratorio de olfatometría. Aplicación de un nue...
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Vol. 56. Issue 10.
Pages 472-476 (December 2005)
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Vol. 56. Issue 10.
Pages 472-476 (December 2005)
Diseño y realización de un laboratorio de olfatometría. Aplicación de un nuevo sistema de valoración
Design and performance of a laboratory of olfactory test. Application of a new evaluation system
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J.I. Alfonso1, H. Vallés, C. Cervera
Hospital Clínico Universitario “Lozano Blesa”. Zaragoza
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Resumen
Objetivo

Diseñar un laboratorio y un test de olfatometría nuevo, para valorar, en estudios que realizaremos posteriormente, los posibles factores que influyan sobre la sensibilidad olfativa humana frente a la piridina

Material y métodos

Hemos diseñado un laboratorio de olfatometría y una sistemática de estudio utilizando la piridina como sustancia odorante. Hemos llevado a cabo un estudio con 30 voluntarios varones, entre 20 y 40 años de edad, para establecer los umbrales de referencia que nos permitan realizar determinaciones posteriores

Resultados

Hemos calculado cuatro concentraciones de piridina; para el estudio de diferentes parámetros de la función olfatoria. El 95% de los voluntarios de la prueba detectaron la concentración más alta de piridina; el resto de las concentraciones nos permitieron establecer la sensibilidad de la población en estudio a los umbrales inferiores

Conclusiones

Hemos diseñado, realizado y homologado un laboratorio de estudio de la olfacción. Hemos determinado la sensibilidad de la población en studio a diversas concentraciones de piridina que pueden ser consideradas como referencias posteriores

Palabras clave:
Olfacción
Laboratorio de olfatometría
Test olfativo
Piridina
Abstract
Background

To study and evaluate the factors that may influence on human olfactory sensibility to pyridine, we designed a specific laboratory with a new olfactory test to perform accurate measurements

Methods

We have chosen pyridine as the test substance in our laboratory, for its frequent use of it in other studies. The special conditions of our laboratory are designed to allow individuals to access to this substance, controlling the different factors and parameters. With this purpose, we have validated the test and we have settled the reference threshold values with the score score of thirty voluntary healthy patients between 20 and 40 years of age

Results

We have used four different concentrations of pyridine to study the different factors of olfactory sensibility. 95% of cases detected the highest pyridine concentration and the remaining concentrations allowed us to know the olfactory sensibility of the studied population and the inferior thresholds

Conclusions

We have designed, performed and endorsed a laboratory for the study of olfaction. We have determined the sensibility of the studied population to different concentrations of pyridine that can be considered as a reference for further studies

Key words:
Olfaction
Laboratory of olfactory test
Olfactory Test
Pyridine

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