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Journal Information
Vol. 57. Issue 6.
Pages 253-256 (July 2006)
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Vol. 57. Issue 6.
Pages 253-256 (July 2006)
Proyecciones centrales del nervio laríngeo recurrente de la rata
Central projections of the rat recurrent laryngeal nerve
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A. Pascual-Font, E. Maranillo, A. Merchán, T. Vázquez, J.R. Sañudo, F.J. Valderrama Canales1
Corresponding author
lfvalde@med.ucm.es

Correspondencia: Francisco J. Valderrama-Canales Departamento de Anatomía y Embriología Humana I. Facultad de Medicina, Universidad Complutense 28040 Madrid
Departamento de Anatomía y Embriología Humana I. Facultad de Medicina. Universidad Complutense de Madrid
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Resumen

Los nervios laríngeos contienen las fibras que controlan la función laríngea. Pocos y discrepantes son los estudios que se han realizado en la rata para conocer los componentes funcionales y el origen real de las fibras que componen el nervio laríngeo recurrente (NLR). En ninguno de estos estudios se ha utilizado dextranos, potentes herramientas para el trazado nervioso. El objetivo de nuestro estudio es identificar en la rata los núcleos de origen de las fibras que porta el NLR, conociendo así los componentes funcionales del mismo, mediante el trazado con dextranos biotinados (BDA). El estudio se ha realizado en 31 ratas Sprague-Dawley machos adultos, aplicando el BDA en el NLR previamente lesionado. Los resultados en todos los animales muestran que el NLR de la rata no ontiene fibras aferentes, mientras que las fibras eferentes se originan en el núcleo ambiguo (NA) ipsilateral. Por lo tanto, en la rata, el NLR parece contener exclusivamente fibras eferentes, debiendo de ser las fibras aferentes conducidas, muy probablemente en su totalidad, por el nervio laríngeo superior.

Palabras clave:
Nervios laríngeos
Laringe
Núcleo ambiguo
Dextrano
Rata
Abstract

Laryngeal nerves contain the fibres that control the laryngeal function. The studies carried out on the rat with the purpose of having a better knowledge of the functional components and the real origin of the fibres conveyed by the recurrent laryngeal nerve (RLN) are few and in disagreement. No one of such papers were developed using biotinylated dextrane amines (BDA), a powerful tool for tracing neural pathways. The aim of our study was to identify in the rat using BDA, the nuclei of real origin of the fibres of the RLN, knowing in this way the functional components of this nerve. The study has been developed in 31 adult male Sprague-Dawley rats, applying the BDA into the lesioned RLN. The results obtained in all the animals show that the rat’s RLN does not contain afferent fibres, whereas the efferent fibres were originated within the ipsilateral nucleus ambiguus (NA). So, in the rat, the RLN seems to contain exclusively efferent fibres, probably been the superior laryngeal nerve who conveyed the afferent fibres.

Key words:
Laryngeal nerves
Larynx
Nucleus ambiguus
Dextran amines
Rat

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