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Inicio Acta Otorrinolaringológica Española Otorhinolaryngological manifestations in monkeypox
Journal Information
Vol. 74. Issue 4.
Pages 263-267 (July - August 2023)
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Vol. 74. Issue 4.
Pages 263-267 (July - August 2023)
Brief communication
Otorhinolaryngological manifestations in monkeypox
Manifestaciones otorrinolaringológicas en la viruela del mono
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4
Berta Alegrea,
Corresponding author
balegre@clinic.cat

Corresponding author.
, Sara Jubésa, Natalia Arangoa, Daniela Pastenea, Eduardo Lehrera,b, Isabel Vilasecaa,b
a Servicio de Otorrinolaringología, Hospital Clínic, Barcelona, Spain
b Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Barcelona, Spain
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Table 1. Clinical characteristics of the series.
Abstract
Background and objective

In the current health emergency declared by the World Health Organization (WHO) for monkeypox, few data on the otorhinolaryngological (ENT) manifestations of the disease have been detailed. The purpose of this study is to describe the clinical features of the ENT manifestations in monkeypox.

Materials and methods

Descriptive analysis of 11 consecutive patients with odynodysphagia or oral cavity lesions referred to the ENT emergency department of a tertiary hospital with epidemiological risk factors suggestive of monkeypox infection. Clinical, diagnostic and treatment findings are described.

Results

90.9% of the patients had previous unsafe sexual contact. The predominant presenting features included fever over 38 °C with severe odynodysphagia. Physical examination showed ulcers and exudative lesions of variable presentation in the upper respiratory tract. Smear of the lesions confirmed polymerase chain reaction (PCR) positivity for monkeypox in all patients.

Conclusions

Monkeypox virus infection can occur in the ENT area with multiple manifestations that require a high degree of epidemiological suspicion and confirmation with PCR to reach a diagnosis of certainty.

Keywords:
Monkeypox
Odynophagia
Tonsillitis
Ulcer
Adenopathy
Unsafe sexual contact
PrEP
Resumen
Antecedentes y objetivo

En la actual emergencia sanitaria declarada por la Organización Mundial de la Salud (OMS) por viruela del mono se han detallado pocos datos sobre las manifestaciones otorrinolaringológicas (ORL) de dicha enfermedad. El propósito del estudio pretende describir las características clínicas de las manifestaciones ORL de la viruela del mono.

Materiales y métodos

Análisis descriptivo de 11 pacientes consecutivos con odinodisfagia o lesiones de cavidad oral derivados al área de urgencias de ORL de un hospital terciario con factores de riesgo epidemiológicos que pudieran sugerir infección por viruela del mono. Se describen los hallazgos clínicos, diagnósticos y de tratamiento.

Resultados

El 90,9% de los pacientes habían tenido contacto sexual de riesgo previo. El cuadro de presentación predominante incluía fiebre de más de 38 °C con odinodisfagia intensa. El examen físico mostraba úlceras y lesiones exudativas de presentación variable en la vía aerodigestiva superior. El frotis de las lesiones confirmó positividad en la reacción en cadena de la polimerasa (PCR) para viruela del mono en todos los pacientes.

Conclusiones

La infección por virus de viruela del mono puede presentarse en el área ORL con múltiples manifestaciones que precisan de un grado de sospecha epidemiológico alto y la confirmación con PCR para llegar a un diagnóstico de certeza.

Palabras clave:
Viruela del mono
Odinofagia
Amigdalitis
Úlcera
Adenopatía
Conducta sexual de riesgo
PrEP

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