Nasal Leprosy: Impact of Multitherapy in the Morphology and Physiology of the Nose
Lepra nasal: impacto de la multiterapia en la morfología y la fisiología nasal
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"apellidos" => "Doménech" ] 5 => array:2 [ "nombre" => "Enrique" "apellidos" => "Perelló" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173573507703307?idApp=UINPBA00004N" "url" => "/21735735/0000005800000005/v1_201304231354/S2173573507703307/v1_201304231354/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "titulo" => "Nasal Leprosy: Impact of Multitherapy in the Morphology and Physiology of the Nose" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "182" "paginaFinal" => "186" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "María Teresa Torres-Larrosa, Luis Jorge Pérez-Pérez, María Vicenta Quintana Ginestar, Vicente Torres-Peris, Juan José Artazkoz del Toro" "autores" => array:5 [ 0 => array:4 [ "nombre" => "María Teresa" "apellidos" => "Torres-Larrosa" "email" => array:1 [ 0 => "matetorres@eresmas.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Luis Jorge" "apellidos" => "Pérez-Pérez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "María Vicenta" "apellidos" => "Quintana Ginestar" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "Vicente" "apellidos" => "Torres-Peris" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 4 => array:3 [ "nombre" => "Juan José" "apellidos" => "Artazkoz del Toro" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicio de Otorrinolaringología, Hospital Universitario Nuestra Señora de Candelaria, Tenerife, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Sanatorio San Francisco de Borja, Fontilles, Alicante, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicio de Dermatología, Hospital Clínico Universitario de Valencia, Valencia, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Correspondence: San Juan Bautista, 16, 1.° A. 38002 Santa Cruz de Tenerife. Tenerife. Islas Canarias. España." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Lepra nasal: impacto de la multiterapia en la morfología y la fisiología nasal" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2007-02-28" "fechaAceptado" => "2007-03-05" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec79900" "palabras" => array:4 [ 0 => "Nose deformities" 1 => "Rhinomanometry" 2 => "Leprosy" 3 => "Multiple leprostatic agents" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec79899" "palabras" => array:4 [ 0 => "Deformidades nasales" 1 => "Rinomanometría" 2 => "Lepra" 3 => "Multiterapia" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The multi-drug therapy protocol has allowed leprosy patients following this strategy to achieve complete recovery without developing neurotrophic sequelae or deformities.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Objectives To assess the impact of multi-drug therapy on the development of nasal deformities and nasal airway patency.</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">In an overall group of 84 patients studied, 38 were treated with a therapy based on a single drug and 22 were treated with multi-drug while 24 subjects formed a control group. Nose morphology was determined by anterior rhinoscopy. Nasal patency and flow resistances were measured by anterior rhinomanometry. The results were compared by using the Anova test for a single variable.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The nasal structures in the group with therapy based on a single drug underwent resorption of bone and cartilage in the structures of the nose and increased flow resistance. In the group receiving the multi-drug protocol, there were no significant morphological alterations and nasal patency and flow resistance remained within normal levels.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The multi-drug therapy is effective in preventing the development of nasal deformities and maintains normal nasal airflow.</p>" ] "es" => array:1 [ "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">El protocolo de terapia combinada ha permitido que los enfermos de lepra tratados según esta estrategia alcancen una curación sin secuelas neurotróficas ni deformidades.</p> <span class="elsevierStyleSectionTitle">Objetivos</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Determinar el impacto de la multiterapia en el desarrollo de las alteraciones del esqueleto óseo cartilaginoso y en la función respiratoria nasal.</p> <span class="elsevierStyleSectionTitle">Pacientes y método</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Estudiamos a 84 sujetos: 38 pacientes tratados con monoterapia, 22 pacientes tratados con multiterapia y 24 sujetos control. Exploramos la morfología nasal mediante rinoscopia anterior y la función respiratoria nasal mediante rinomanometría anterior activa. En el análisis estadístico se ha utilizado el test ANOVA de un factor.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">En el grupo de monoterapia observamos una reabsorción osteocartilaginosa de las estructuras nasales y un aumento de las resistencias nasales. Los pacientes que recibieron multiterapia no presentaron cambios morfológicos significativos y la función respiratoria nasal se mantuvo dentro de la normalidad.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">La terapia combinada es eficaz porque previene la aparición de deformidades nasales y la insuficiencia respiratoria nasal.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:16 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical manifestations of leprous rhinitis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "R.P.E. Barton" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Ann Otol" "fecha" => "1976" "volumen" => "85" "paginaInicial" => "74" "paginaFinal" => "82" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The histopathology of lepromatous leprosy in the nose" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.C. McDougall" 1 => "R.J.W. Rees" 2 => "A.G.M. Weddell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Pathol" "fecha" => "1974" "volumen" => "108" "paginaInicial" => "24" "paginaFinal" => "29" ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Clinical and histological studies of the nose in early lepromatous leprosy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R.P.F. Barton" 1 => "T.F. Davey" 2 => "A.C. McDougall" 3 => "R.J.W. Rees" 4 => "A.G.M. Weddell" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:4 [ "tituloSerie" => "Int J Lepr" "fecha" => "1973" "volumen" => "41" "paginaInicial" => "512" ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The nasal mucus in leprosy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "J.C. Pedley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lepr Rev" "fecha" => "1973" "volumen" => "44" "paginaInicial" => "33" "paginaFinal" => "35" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/4584261" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The nasal excretion of M. leprae in leprosy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "C.C. Shepard" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Lepr" "fecha" => "1962" "volumen" => "30" "paginaInicial" => "10" "paginaFinal" => "18" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13911662" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lepromatous leprosy of the nose after one year of dapsone treatment: histopathology findings" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.C. McDougall" 1 => "A.G.M. Weddell" 2 => "R.J.W. Rees" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Lepr Rev" "fecha" => "1975" "volumen" => "46" "paginaInicial" => "267" "paginaFinal" => "277" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1107726" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The nose in lepromatous leprosy; bacteriological and histopathological studies of patients treated with dapsone monotherapy for varying periods of time" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R.P.E. Barton" 1 => "R.J.W. Rees" 2 => "A.C. McDougall" 3 => "G.A. Ellard" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Int J Lepr" "fecha" => "1982" "volumen" => "50" "paginaInicial" => "58" "paginaFinal" => "67" ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The histopathological appearance of leprous rhinitis and pathogenesis of septal perforation in leprosy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "C.K. Job" 1 => "A.B.A. Karat" 2 => "S. Karat" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Laryngol Otol" "fecha" => "1966" "volumen" => "80" "paginaInicial" => "718" "paginaFinal" => "732" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/5940434" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Facial and oral manifestation in leprosy: an evaluation of 67 cases" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "P. Reichart" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Oral Surg" "fecha" => "1976" "volumen" => "41" "paginaInicial" => "385" "paginaFinal" => "399" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/1061926" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib10" "etiqueta" => "10." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "WHO Study Group. Chemotherapy of leprosy for control programme. Technical Report Series N.°. 657. Geneva: WHO; 1982." ] ] ] 10 => array:3 [ "identificador" => "bib11" "etiqueta" => "11." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Report of a consultation on implementation of multidrug therapy for leprosy control (R 786). Geneva: WHO; 1985." ] ] ] 11 => array:3 [ "identificador" => "bib12" "etiqueta" => "12." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Multidrug therapy in the control of leprosy: a field study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "M. Becx-Bleumink" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Trop Georg Med" "fecha" => "1994" "volumen" => "46" "paginaInicial" => "109" "paginaFinal" => "114" ] ] ] ] ] ] 12 => array:3 [ "identificador" => "bib13" "etiqueta" => "13." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "An international randomised study with long term follow up of single versus combination chemotheray of multibacillary leprosy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "M. Dietrich" 1 => "W. Gaus" 2 => "P. Kern" 3 => "W.M. Meyers" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Antimicrob Agents Chemother" "fecha" => "1994" "volumen" => "38" "paginaInicial" => "2249" "paginaFinal" => "2257" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7840553" "web" => "Medline" ] ] ] ] ] ] ] ] 13 => array:3 [ "identificador" => "bib14" "etiqueta" => "14." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Leprosy in French polynesia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "J.L. Cartel" 1 => "A. Spiegel" 2 => "N.L. Nguyen" 3 => "J.P. Moulia-Pelat" 4 => "P.M.V. Martin" 5 => "J.H. Grosset" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "The possible impact of multidrug therapy on epidemiological trends. Lepr Rev" "fecha" => "1992" "volumen" => "63" "paginaInicial" => "223" "paginaFinal" => "230" ] ] ] ] ] ] 14 => array:3 [ "identificador" => "bib15" "etiqueta" => "15." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Deformity incidence in leprosy patients treated with multidrug therapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "P.S. Rao" 1 => "M. Subramaniam" 2 => "G. Subramanian" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Ind J Lepr" "fecha" => "1994" "volumen" => "66" "paginaInicial" => "449" "paginaFinal" => "454" ] ] ] ] ] ] 15 => array:3 [ "identificador" => "bib16" "etiqueta" => "16." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Changes in the anterior nasal spine and the alveolar process of the maxillary bone" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "V. Möller-Christensen" 1 => "S.N. Bakke" 2 => "R.S. Melsom" 3 => "E. Waaler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Int J Lepr" "fecha" => "1952" "volumen" => "20" "paginaInicial" => "335" "paginaFinal" => "340" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/13010888" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735735/0000005800000005/v1_201304231354/S2173573507703319/v1_201304231354/en/main.assets" "Apartado" => array:4 [ "identificador" => "5871" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Original articles" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735735/0000005800000005/v1_201304231354/S2173573507703319/v1_201304231354/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173573507703319?idApp=UINPBA00004N" ]
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| 2023 November | 0 | 1 | 1 |
| 2023 October | 0 | 2 | 2 |
| 2023 August | 0 | 1 | 1 |
| 2023 July | 0 | 3 | 3 |
| 2023 June | 0 | 2 | 2 |
| 2023 April | 0 | 1 | 1 |
| 2023 March | 0 | 3 | 3 |
| 2023 January | 0 | 2 | 2 |
| 2022 December | 0 | 1 | 1 |
| 2022 September | 0 | 1 | 1 |
| 2022 July | 0 | 4 | 4 |
| 2022 June | 0 | 3 | 3 |
| 2022 April | 0 | 1 | 1 |
| 2021 February | 0 | 1 | 1 |
| 2020 September | 0 | 3 | 3 |
| 2020 May | 0 | 1 | 1 |
| 2020 March | 4 | 7 | 11 |
| 2020 February | 7 | 9 | 16 |
| 2020 January | 4 | 6 | 10 |
| 2019 December | 16 | 20 | 36 |
| 2019 November | 4 | 5 | 9 |
| 2019 October | 4 | 4 | 8 |
| 2019 September | 5 | 3 | 8 |
| 2019 August | 2 | 8 | 10 |
| 2019 July | 5 | 7 | 12 |
| 2019 June | 4 | 21 | 25 |
| 2019 May | 30 | 67 | 97 |
| 2019 April | 4 | 34 | 38 |
| 2019 March | 2 | 6 | 8 |
| 2019 February | 2 | 12 | 14 |
| 2019 January | 0 | 9 | 9 |
| 2018 December | 0 | 11 | 11 |
| 2018 November | 4 | 13 | 17 |
| 2018 October | 6 | 5 | 11 |
| 2018 July | 0 | 1 | 1 |
| 2018 April | 1 | 5 | 6 |
| 2018 March | 0 | 1 | 1 |
| 2018 February | 2 | 2 | 4 |
| 2018 January | 1 | 2 | 3 |
| 2017 November | 1 | 3 | 4 |
| 2017 October | 2 | 3 | 5 |
| 2017 September | 3 | 3 | 6 |
| 2017 August | 3 | 5 | 8 |
| 2017 July | 2 | 1 | 3 |
| 2017 June | 5 | 2 | 7 |
| 2017 May | 15 | 1 | 16 |
| 2017 April | 5 | 1 | 6 |
| 2017 March | 16 | 33 | 49 |
| 2017 February | 5 | 5 | 10 |
| 2017 January | 4 | 1 | 5 |
| 2016 December | 3 | 0 | 3 |
| 2016 November | 5 | 3 | 8 |
| 2016 October | 5 | 3 | 8 |
| 2016 September | 3 | 1 | 4 |
| 2016 August | 4 | 0 | 4 |
Show all