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Neuroendocrine carcinomas in otolaryngology: A difficult diagnosis
Carcinomas neuroendocrinos en ORL: Un diagnóstico difícil
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Navazo-Eguía, David Conejo-Moreno, Gregorio De-La-Mata-Franco, Alicia Clemente-García" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Ana I." "apellidos" => "Navazo-Eguía" ] 1 => array:2 [ "nombre" => "David" "apellidos" => "Conejo-Moreno" ] 2 => array:2 [ "nombre" => "Gregorio" "apellidos" => "De-La-Mata-Franco" ] 3 => array:2 [ "nombre" => "Alicia" "apellidos" => "Clemente-García" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173573511700084?idApp=UINPBA00004N" "url" => "/21735735/0000006200000001/v1_201304231449/S2173573511700084/v1_201304231449/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Brief communication</span>" "titulo" => "Neuroendocrine carcinomas in otolaryngology: A difficult diagnosis" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "51" "paginaFinal" => "55" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Milagros Marcos, Guillermo Landínez, Gerardo Martínez, Darío Moráis" "autores" => array:4 [ 0 => array:4 [ "nombre" => "Milagros" "apellidos" => "Marcos" "email" => array:1 [ 0 => "mmarcoso@med.uva.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Guillermo" "apellidos" => "Landínez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "Gerardo" "apellidos" => "Martínez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "Darío" "apellidos" => "Moráis" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Otorrinolaringología, Valladolid, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Hospital Clínico Universitario, Valladolid, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "*" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Carcinomas neuroendocrinos en ORL: Un diagnóstico difícil" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-12-28" "fechaAceptado" => "2010-02-11" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec81659" "palabras" => array:4 [ 0 => "Neuroendocrine tumours of the head and neck" 1 => "Larynx" 2 => "Paranasal sinuses" 3 => "Neoplasm metastases" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec81658" "palabras" => array:4 [ 0 => "Tumores neuroendocrinos de cabeza y cuello" 1 => "Laringe" 2 => "Senos paranasales" 3 => "Metástasis cervicales" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Neuroendocrine carcinomas of the head and neck are infrequent. They appear as original tumours in this area, or more frequently as lymph node metastasis, while some of them are of unknown origin. We describe four cases diagnosed by pathological study of neuroendocrine carcinomas in the head and neck area since 2002. All of the cases were male, with a mean age of 59 years. In the two primary cases, the tumours were located inside the maxillary sinus and larynx; the other two were cases of cervical metastasis originating outside of the head and neck area. Three of them died in less than 18 months. We emphasise the wide distribution this kind of tumours has and the varying forms of associating; these factors make it difficult to join the symptomatology into a single group, as well as to arrive at the diagnosis and to carry out treatment.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Los carcinomas neuroendocrinos de cabeza y cuello son poco frecuentes. Se presentan como foco primario en esta área, o más frecuentemente como metástasis ganglionar cervical, pudiendo, en muchos casos, formar parte de los tumores de origen desconocido.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Presentamos 4 casos diagnosticados por estudio anatomopatológico de carcinomas neuroendocrinos pobremente diferenciados desde el año 2002, en área ORL, todos ellos varones con una edad promedio de 59 años. En 2, el foco primario se localiza en el seno maxilar y en la laringe; los otros 2 como metástasis cervicales de focos fuera de área ORL. Tres fallecieron en menos de 18 meses.</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Hacemos hincapié en la amplia distribución y diversas formas de agruparse, lo que hace difícil reunir en un solo conjunto la sintomatología, así como llegar al diagnóstico y efectuar su tratamiento.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:9 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Thomassin JM, Deveze A, Chrestian MA. Sistema Neuroendocrino difuso y patología cervicofacial. Encyclopédie Médico-Chirurgicale - E-20-945-A-10. 2002." ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." 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ORL-DIPS soor, 31:162–4." ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735735/0000006200000001/v1_201304231449/S2173573511700096/v1_201304231449/en/main.assets" "Apartado" => array:4 [ "identificador" => "5882" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Brief Communication" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735735/0000006200000001/v1_201304231449/S2173573511700096/v1_201304231449/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173573511700096?idApp=UINPBA00004N" ]
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