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Paediatric nasal dermoids: Our experience
Dermoides nasales pediátricos: nuestra experiencia
Ravi Meher, Avani Jain
Corresponding author
avanijain87@hotmail.com

Corresponding author.
, Ishwar Singh, Nivea Singh, Raman Sharma
Department of ENT, MAMC, New Delhi, India
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Midline congenital lesions of the nose are rare&#44; occurring in 1&#58;20&#44;000&#8211;40&#44;000 births&#46;<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">1&#44;2</span></a> These include nasal dermoids&#44; nasal gliomas and encephaloceles&#46; Among these&#44; nasal dermoid are the most frequently encountered&#46; Nasal dermoid is a midline anomaly that can present as a cyst&#44; sinus or fistula and may have an intracranial extension&#46;<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">3</span></a> The pathogenesis involves incomplete obliteration of the neuroectoderm during development of the frontonasal process&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">4</span></a> It is lined by stratified squamous epithelium and contains both ectodermal and mesodermal elements&#44; including adnexal structures and sebaceous glands&#46; It may appear anywhere from the glabella&#44; along the bridge of the nose&#44; to the base of the columella&#46; Patients may present with facial swelling or infection&#46; There may be intermittent discharge of sebaceous material or pus&#44; abscess&#44; osteomyelitis&#44; broadening of the nasal root or bridge and&#47;or intracranial complications&#46; Timely diagnosis and appropriate surgical management are essential to avoid complications and prevent progressive enlargement&#46; Complete excision of nasal dermoid cyst sinus&#44; regardless of its extension&#44; is essential to prevent recurrence&#44; infection&#44; meningitis and intracranial abscess formation&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">This retrospective study evaluates our experience of the clinical presentation&#44; imaging and surgical findings of nasal dermoids&#46; The contribution of computed tomography &#40;CT&#41; and magnetic resonance imaging &#40;MRI&#41; in preoperative surgical planning was also studied&#46; Given the rarity of these lesions&#44; large studies are difficult to acquire&#46; Also&#44; most of the studies reported till date are from the Western world and there is lack of data from developing countries like India&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Methods</span><p id="par0015" class="elsevierStylePara elsevierViewall">A retrospective analysis of patients admitted for the treatment of nasal dermoid between 2012 and 2017 was done&#46; A total of 10 patients were included in the study&#46; We reviewed the patient presentation&#44; preoperative imaging &#40;CT&#47;MRI&#41;&#44; surgical approach&#44; intraoperative findings&#44; complications and recurrence&#46; Imaging findings were compared with intraoperative surgical findings to evaluate their accuracy to diagnose intracranial extension&#46; The diagnosis in each case was confirmed by surgical pathology&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Results</span><p id="par0020" class="elsevierStylePara elsevierViewall">A total of 10 patients were included in this study&#44; 6 were males and 4 were females &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#41;&#46; The age at time of presentation ranged from 4 to 18 years of age&#44; with an average of 10&#46;2 years&#46; There was no significant family history or associated craniofacial anomaly in any of the patients&#46; One patient had an associated branchial sinus&#46; There was no history of intracranial infections or meningitis&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">Three patients presented with a mass located on the nasal dorsum&#44; 1 had a nasoglabellar mass &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#44; 2 patients has a mass located on nasal dorsum with visible sinus&#44; and 4 patients presented with a sinus on the nasal dorsum &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41; out of which 1 patient had a tuft of hair &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46; Four patients presented with asymptomatic masses and sought consultation for cosmetic purposes&#44; whereas the remaining six patients presented due to recurrent infections and discharging sinuses&#44; as well as cosmesis&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">All the patients underwent preoperative imaging to determine the extent of lesion and rule of intracranial extension&#46; CT scan was done in all the cases&#46; As per the CT scan findings&#44; there was no intracranial extension in 9 patients&#44; and was non-diagnostic in one patient&#46; Both CT and MRI were done in 2 patients&#44; with no evidence of intracranial extension&#46; No patients were found to have associated intracranial anomaly on CT and MRI scan&#46; Surgical and radiological findings were concordant in 8 patients &#40;80&#37;&#41;&#46; In one patient&#44; the intracranial extension was not noted on CT but was evident intraoperatively as the sinus extended up to but did not breach the dura&#46; There was a defect in the floor of the anterior cranial fossa but dura was intact&#46; In another patient&#44; intraosseous extension of the sinus tract was not noted on CT but was evident intraoperatively&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">The surgical approach and findings of each of the patients is mentioned in <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a>&#46; The patients were classified according to Hartley et al&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">5</span></a> into superficial&#44; intraosseous&#44; intracranial extradural and intracranial intradural&#46; In all cases&#44; the diagnosis of nasal dermoid sinus cyst was confirmed pathologically&#46; There were no major intraoperative or postoperative complications&#46; All the patients were followed up for one year&#44; with no evidence of recurrence or altered nasal bone development and significant deformity during the follow up period&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Discussion</span><p id="par0040" class="elsevierStylePara elsevierViewall">Nasal dermoid sinus cysts are rare congenital anomalies&#44; that are commonly present at birth or soon after&#46; They have a male predominance&#46;<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">6</span></a> These lesions are occasionally known to be familial&#46;<a class="elsevierStyleCrossRefs" href="#bib0110"><span class="elsevierStyleSup">7&#44;8</span></a> In this series&#44; none of our patients had a positive family history or other associated craniofacial anomalies&#46; One patient had an associated branchial sinus&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">The average age at time of presentation in our study was 10&#46;2 years&#46; This was much higher as compared other studies&#44; Bloom et al&#46;<a class="elsevierStyleCrossRef" href="#bib0120"><span class="elsevierStyleSup">9</span></a> &#8211; 3 months&#44; El-fattah et al&#46;<a class="elsevierStyleCrossRef" href="#bib0125"><span class="elsevierStyleSup">10</span></a> &#8211; 2&#46;5 years&#44; Hartley et al&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">5</span></a> &#8211; 29 months&#44; Herrington et al&#46;<a class="elsevierStyleCrossRef" href="#bib0130"><span class="elsevierStyleSup">11</span></a> &#8211; 3&#46;1 years&#44; Ortlip et al&#46;<a class="elsevierStyleCrossRef" href="#bib0135"><span class="elsevierStyleSup">12</span></a> &#8211; 1 year&#46; The possible causes in a developing country&#44; like ours&#44; could be low socioeconomic status&#44; illiteracy&#44; large families with single earning member and no access to health care facility in villages&#46; These factors lead to a delay in seeking treatment&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">These lesions usually present as a midline swelling on the nasal dorsum and may be associated with a sinus opening and intermittent discharge of sebaceous material and recurrent infection&#46; Hair may emerge from the sinus opening and is considered pathognomonic for nasal dermoid&#46; Masses are often present at birth or soon after&#44; progressively increase in size&#44; with or without recurrent infections&#46; Patients may present with a history of recurrent infections or due to cosmetic concerns&#46; In this study&#44; the main reason for consultation was for cosmesis&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Intracranial extension has been well described in literature&#44; with most series reporting a rate between 4 and 57&#37;&#46;<a class="elsevierStyleCrossRefs" href="#bib0105"><span class="elsevierStyleSup">6&#44;13</span></a> All patients with nasal dermoids should be considered as having intracranial extension&#44; unless proved otherwise&#46;<a class="elsevierStyleCrossRef" href="#bib0105"><span class="elsevierStyleSup">6</span></a> Intracranial extension may be extradural or intradural&#46; Fortunately&#44; most of the patients with intracranial extension are extradural&#46; The intracranial tract traverses the foramen caecum or cribriform plate to reach the anterior skull base and adhere to the falx cerebri extradurally&#46; Intracranial infection in the form of meningitis&#44; cavernous sinus thrombosis and periorbital cellulitis has been reported following nasal dermoid infection&#44; but this was not seen in our series&#46;<a class="elsevierStyleCrossRefs" href="#bib0145"><span class="elsevierStyleSup">14&#44;15</span></a> 4 of our patients had abscess formation and secondary fistula formation at the nasal dorsum&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">Preoperative imaging is essential to confirm the diagnosis and to rule out other intracranial anomalies&#46; It also helps to determine the extent of the lesion and intracranial extension&#44; thereby facilitating complete surgical resection&#46; Preoperative imaging includes CT&#44; and complementary MRI should be considered in suspected intracranial extension&#46; However&#44; some authors consider that MRI alone is the most accurate and cost-effective means of evaluating nasal dermoids&#46; The established criteria for intracranial extension on CT include a bifid crista galli process and enlargement of the foramen caecum&#46; The interpretation of CT in young children may be hindered because the lamina perpendicularis of the ethmoid bone and the crista galli frequently are not ossified&#44; which can be mistaken for intracranial extension&#46; Positive predictive values reported in CT and MRI are 85&#46;7&#37; and 100&#37;&#44; respectively&#46; Negative predictive values have been estimated at 50&#37; for CT and MRI&#46; In our study&#44; CT was done in all the patients and both CT and MRI was only done in two patients&#46; Due to the higher cost of MRI&#44; the patients could not afford the scan&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Complete surgical excision of nasal dermoid cyst and any associated sinus tract is essential for cure&#46; Any residual ectodermal elements may result in a high rate of recurrence and complications&#46; Recurrence has been estimated at 50&#8211;100&#37; if resection is incomplete&#46; As proposed by Pollock&#44; the surgical approach chosen to excise a nasal dermoid should adhere to four principles&#58; should allow adequate exposure to the mass and associated sinus tract&#44; should allow access to the skull base&#44; should provide exposure for reconstruction of the nasal dorsum&#44; and should result in a cosmetically acceptable scar&#46; Surgical approach depends on the locations and extent of the lesion&#44; ranging from local excision to a combined intracranial&#8211;extracranial approach&#46; The patients&#8217; cosmetic concerns must also be taken into account&#46; Multiple approaches have been described&#44; including vertical incision&#44; transverse incision&#44; lateral rhinotomy&#44; medial paracanthal&#44; U-shaped dorsal incision&#44; external rhinoplasty&#44; degloving procedure&#44; transglabellar incision&#44; brow incision&#44; and bicoronal incision&#46; Traditionally&#44; for removal of intracranial extension&#44; bifrontally craniotomy was done&#46; This was associated with a high morbidity and high complication rate&#46; The complications may include meningitis&#44; hyposmia&#44; CSF leak&#44; damage to frontal and sagittal sinus&#44; epilepsy&#44; frontal bone osteomyelitis and occasionally&#44; intracerebral hemorrhage&#44; cerebral edema and memory loss&#46; In recent years&#44; however&#44; both subcranial and endoscopic approaches have been proposed&#44; in order to reduce the morbidity&#46; Kellman et al&#46; described transglabellar subcranial approach for nasal dermoids with intracranial extension&#44; with no recurrence or negative effect on craniofacial growth&#46; Weiss et al&#46; have described successful transnasal endoscopic excision of nasal dermoid with intracranial extension&#44; without need for craniotomy&#46; This technique was not recommended for dermoids extending into or beyond falx cerebri&#46; Recently&#44; however&#44; successful endoscopic resection of intradural intracranial nasal dermoid have been reported&#46; Schuster et al&#46; reported successful endoscopic removal of two intracranial dermoids extending to anterior frontal lobe&#44; with a pedicled nasoseptal flap to close the skull base defect&#46; Duz et al&#46; described endoscopic excision of a cystic lesion located in the anterior subfrontal region&#46; The transnasal approach meets all the criteria recommended by Pollock for resection of intracranial extension of nasal dermoid&#44; with no external scar&#46; Also&#44; the morbidity and complications associated with frontal craniotomy are minimized&#44; thereby facilitating early post operative recovery and shorter hospital stay&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">In this series&#44; the lesions were predominantly superficial and involved local excision and direct closure&#46; The cases reported in this series have been classified according to the deep extent of the lesion &#40;Hartley et al&#46;&#41;&#44; which allows precise surgical planning&#46; The most common superficial lesions remain within the soft tissue and were easily excised&#46; Intraosseous lesions required drilling of nasal or frontal bone for complete excision&#46; Intracranial extradural lesion was excised by Lynch incision and limited frontonasal craniotomy and was peeled off the dura&#46; This avoided any major complications associated with bifrontal craniotomy&#46; There were no intraoperative or post operative complications in our study&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">This study has several limitations&#46; First&#44; this is a retrospective study with a small sample number of patients&#46; Also&#44; most of our patients&#44; belonging to lower socioeconomic strata&#44; could not afford complete pre operative imaging&#46; However&#44; given the rarity of these lesions&#44; large studies are difficult to acquire&#46; Also&#44; most of the studies reported till date are from the Western countries&#44; and there is lack of data from developing countries like ours&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Conclusion</span><p id="par0080" class="elsevierStylePara elsevierViewall">Nasal dermoids are uncommon congenital midline lesions presenting with nasal swelling or sinus tract opening on the skin&#46; Preoperative imaging &#40;CT and MRI&#41; is essential to rule out intracranial extension and other associated anomalies&#46; The new classification proposed by Hartley et al&#46;&#44; is a useful system for describing such lesions and allows precise surgical planning&#46; When identified&#44; early and complete surgical excision is mandatory to reduce the risk or recurrent infections&#44; deformity and recurrence&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Source of funding</span><p id="par0085" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Conflicts of interest</span><p id="par0090" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span></span>"
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    "fechaRecibido" => "2018-06-25"
    "fechaAceptado" => "2018-12-05"
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          "clase" => "keyword"
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            0 => "Nasal dermoid"
            1 => "Congenital nasal lesion"
            2 => "Pediatric"
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          "palabras" => array:3 [
            0 => "Dermoide nasal"
            1 => "Lesi&#243;n nasal cong&#233;nita"
            2 => "Pedi&#225;trico"
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        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objectives</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Nasal dermoids are rare developmental anomalies seen in children&#46; This study reports our experience in a developing country of the clinical and radiological findings as well as the management of nasal dermoids&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A retrospective analysis was performed&#44; from 2012 to 2017&#44; for 10 patients admitted for the treatment of nasal dermoids at a tertiary care center&#46; The clinical presentation&#44; preoperative imaging &#40;CT&#47;MRI&#41;&#44; surgical approach&#44; intraoperative findings&#44; complications and recurrence were reviewed&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Ten patients were included in this study&#44; 6 males and 4 females&#44; with an average age of 10&#46;2 years at the time of presentation&#46; Three patients presented with a mass located on the nasal dorsum&#44; 1 had a nasoglabellar mass&#44; 2 patients had a mass located on the nasal dorsum with visible sinus&#44; and 4 patients presented with a sinus on the nasal dorsum&#44; in which 1 patient had a tuft of hair&#46; CT was performed in all the cases&#46; It was not suggestive of intracranial extension in 9 patients&#44; and was non-diagnostic in one patient&#46; Both CT and MRI were performed on 2 patients&#44; with no evidence of intracranial extension&#46; Surgical and radiological findings were concordant in 8 patients &#40;80&#37;&#41;&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conclusion</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Nasal dermoids require preoperative imaging and precise surgical planning to achieve complete removal&#46;</p></span>"
        "secciones" => array:4 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Objectives"
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          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Methods"
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          2 => array:2 [
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            "titulo" => "Results"
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        "resumen" => "<span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Objetivos</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Los dermoides nasales son anomal&#237;as del desarrollo poco frecuentes que se observan en ni&#241;os&#46; Este estudio informa de nuestra experiencia&#44; en un pa&#237;s en desarrollo&#44; de los hallazgos cl&#237;nicos y radiol&#243;gicos&#44; as&#237; como el manejo de los dermoides nasales&#46;</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">M&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se realiz&#243; un an&#225;lisis retrospectivo&#44; desde 2012-2017&#44; para 10 pacientes ingresados &#63;&#63;para el tratamiento de dermoide nasal en un instituto de nivel terciario&#46; Se revisaron la presentaci&#243;n cl&#237;nica&#44; las im&#225;genes preoperatorias &#40;TC&#47;RM&#41;&#44; el abordaje quir&#250;rgico&#44; los hallazgos intraoperatorios&#44; las complicaciones y la recurrencia&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 10 pacientes en este estudio&#44; 6 varones y 4 mujeres&#44; con una edad promedio de 10&#44;2 a&#241;os en el momento de la presentaci&#243;n&#46; Tres pacientes presentaban una masa localizada en el dorso nasal&#44; uno ten&#237;a una masa nasoglabellar&#44; 2 pacientes presentaban una masa localizada en el dorso nasal con seno visible y 4 pacientes presentaban un seno en el dorso nasal&#44; de los cuales un paciente ten&#237;a un mech&#243;n de pelo&#46; La TC se realiz&#243; en todos los casos&#46; No sugiri&#243; una extensi&#243;n intracraneal en 9 pacientes y no fue diagn&#243;stico en un paciente&#46; Tanto la TC como la RM se realizaron en 2 pacientes&#44; sin evidencia de extensi&#243;n intracraneal&#46; Los hallazgos quir&#250;rgicos y radiol&#243;gicos fueron concordantes en 8 pacientes &#40;80&#37;&#41;&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Conclusi&#243;n</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Los dermoides nasales requieren im&#225;genes preoperatorias y una planificaci&#243;n quir&#250;rgica precisa para lograr una extracci&#243;n completa&#46;</p></span>"
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          "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">&#40;a&#41; Clinical photograph of discharging sinus nasal dorsum&#44; &#40;b&#41; MRI showing intraosseous extension of sinus&#46;</p>"
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">S&#46; no&#46;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Age&#47;sex&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Presentation&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Imaging&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Surgical approach&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Surgical findings&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Classification &#40;Bradley&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#47;F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Discharging sinus nasal dorsum with tuft of hair&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CT&#59; no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vertical incision&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Sinus tract with no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t">Superficial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">18&#47;M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mass on nasal dorsum&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CT&#59; no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vertical incision&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2<span class="elsevierStyleHsp" style=""></span>cm mass with no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Superficial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#47;F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Discharging sinus nasal dorsum&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CT &#38; MRI&#59; no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vertical incision&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2<span class="elsevierStyleHsp" style=""></span>cm sinus tract with no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Intraosseous&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#47;F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mass with pit on nasal dorsum&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CT&#59; no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vertical incision&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#46;5<span class="elsevierStyleHsp" style=""></span>cm mass with no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Superficial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#47;M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Nasoglabellar mass&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CT&#59; no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Lynch incision&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1<span class="elsevierStyleHsp" style=""></span>cm mass with intracranial extradural extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Intracranial extradural&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#47;M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Discharging sinus nasal dorsum&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CT&#59; no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vertical incision&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Sinus tract with no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Intraosseous&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#47;M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mass on nasal dorsum&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CT&#59; no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vertical incision&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1<span class="elsevierStyleHsp" style=""></span>cm mass with no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Superficial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#47;F&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Discharging sinus nasal dorsum&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CT&#59; no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vertical incision&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Sinus tract with no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Intraosseous&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#47;M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Mass with pit on nasal dorsum&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CT&#59; no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vertical incision&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1<span class="elsevierStyleHsp" style=""></span>cm mass with no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Superficial&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="char" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">17&#47;M&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Discharging sinus nasal dorsum&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">CT &#38; MRI&#59; no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Vertical incision&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1<span class="elsevierStyleHsp" style=""></span>cm sinus tract with no intracranial extension&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">Intraosseous&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2242935.png"
              ]
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        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Characteristics of nasal dermoid patients&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
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            0 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Midline cysts of the nasal dorsum&#58; embryologic origin and treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "L&#46;W&#46; Pratt"
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                    0 => array:2 [
                      "doi" => "10.1288/00005537-196506000-0010"
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                        "tituloSerie" => "Laryngoscope"
                        "fecha" => "1965"
                        "volumen" => "75"
                        "paginaInicial" => "968"
                        "paginaFinal" => "980"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14301067"
                            "web" => "Medline"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Management of the congenital midline nasal mass&#58; a review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "G&#46;B&#46; Hughes"
                            1 => "G&#46; Sharpino"
                            2 => "W&#46; Hunt"
                            3 => "H&#46;M&#46; Tucker"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1002/hed.2890020308"
                      "Revista" => array:6 [
                        "tituloSerie" => "Head Neck Surg"
                        "fecha" => "1980"
                        "volumen" => "2"
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                        "paginaFinal" => "233"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7353954"
                            "web" => "Medline"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Nasal dermal sinuses&#58; new concepts and explanations"
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46;B&#46; Sessions"
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                    0 => array:1 [
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                        "paginaInicial" => "1"
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                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7132527"
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              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Transnasal endoscopic excision of midline nasal dermoid from the anterior cranial base"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "D&#46;D&#46; Weiss"
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                    0 => array:2 [
                      "doi" => "10.1097/00006534-199811000-00048"
                      "Revista" => array:6 [
                        "tituloSerie" => "Plast Reconstr Surg"
                        "fecha" => "1998"
                        "volumen" => "102"
                        "paginaInicial" => "2119"
                        "paginaFinal" => "2123"
                        "link" => array:1 [
                          0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Nasal dermoids in children&#58; a proposal for a new classification based on 103 cases at Great Ormond Street Hospital"
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                          "etal" => true
                          "autores" => array:6 [
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                    0 => array:2 [
                      "doi" => "10.1016/j.ijporl.2014.10.020"
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                        "tituloSerie" => "Int J Pediatr Otorhinolaryngol"
                        "fecha" => "2015"
                        "volumen" => "79"
                        "paginaInicial" => "18"
                        "paginaFinal" => "22"
                        "link" => array:1 [
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                0 => array:2 [
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                      "titulo" => "Nasal dermoid sinus cysts in children"
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                          "etal" => false
                          "autores" => array:4 [
                            0 => "F&#46; Denoyelle"
                            1 => "V&#46; Ducroz"
                            2 => "G&#46; Roger"
                            3 => "E&#46;N&#46; Garabedian"
                          ]
                        ]
                      ]
                    ]
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                    0 => array:2 [
                      "doi" => "10.1097/00005537-199706000-00014"
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