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Inicio Actas Urológicas Españolas Tratamiento de la cistitis hemorrágica por ciclofosfamida. Revisión de la lite...
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Vol. 29. Issue 2.
Pages 230-233 (January 2005)
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Vol. 29. Issue 2.
Pages 230-233 (January 2005)
Tratamiento de la cistitis hemorrágica por ciclofosfamida. Revisión de la literatura a propósito de un caso
Treatment Of Hemorrhagic Cystitis Secondary To Cyclophosphamide. Literature Review With Regard To A Case
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P. Serrano Frago1
Corresponding author
pserranof@comz.org

Dra. P. Serrano Frago Lapuyade, 19 - 1º A 50007 Zaragoza
, C. Allepuz Losa, P. Gil Martínez, M. Allué López, E. Mallén Mateo, C. Sancho Serrano, L.A. Rioja Sanz
Servicio de Urología. Hospital Universiario Miguel Servet. Zaragoza
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Resumen

Existen situaciones límites en la práctica clínica de hematurias rebeldes a tratamiento, no muy frecuentes hoy en día afortunadamente, en la que por procesos incluso benignos corre serio riesgo la vida del paciente y se plantean actuaciones como la cistectomia.

Es nuestro deseo hacer una revisión de las diversas opciones terapéuticas que existen ante una hematuria intensa que no cede con irrigación continua de suero salino. Recientemente se ha precisado el uso de diferentes técnicas en un paciente joven, que tras administración de ciclofosfamida se controlo la hematuria recurrente e intensa mediante irrigación intravesical de alumina, evitando así una cirugía tan agresiva y con tantas secuelas como la cistectomía.

Palabras clave:
Hematuria
Ciclofosfamida
Alumina
Abstract

There are extreme situations in the clinical treatment of intractable hematuria (fortunately not a common disease nowadays), in which even benign process may represent a serious risk to the life of the patient and where certain aggressive procedures like cystectomy have to be considered.

Our objective in this paper is to review the different existing therapeutic alternatives for the treatment of an intense type of hematuria which does not yield to continuous saline serum irrigation. This study is partly based on a recent real clinical case in which, after the administration of cyclophosphamide to a young patient with recurrent and intense hematuria, the excretion was controlled through intravesical alum irrigation of thus avoiding cystectomy, a very aggressive surgical procedure with many after-effects.

Key words:
Cyclophosphaide
Haematuria
Alum irrigation

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