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Letter to the Editor
Mixed epithelial and stromal tumor of the kidney
Tumor mixto epitelial-estromal renal
M.E. Martínez-Corrala,
Corresponding author
memartinezc92@gmail.com

Corresponding author.
, J.J. Núñez-Oteroa, V. Toucedo-Caamañoa, S.M. García-Acuñab, R. García-Figueirasc, C. García-Freirea
a Servicio de Urología, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
b Servicio de Anatomía Patológica, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
c Servicio de Radiodiagnóstico, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, Spain
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Mixed epithelial and stromal tumors &#40;MEST&#41; of renal origin were first described by Michal and Syrucek in 1998&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> They are grouped&#44; along with adult cystic nephroma&#44; within mixed epithelial and mesenchymal tumors&#44; according to the 2016 World Health Organization classification of renal tumors&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Below&#44; we describe the case of a 46-year-old male who presented to the emergency department for progressive abdominal distention&#46; A computed tomography &#40;CT&#41; scan of the abdomen and pelvis with intravenous contrast showed a heterogeneous lesion initially suspicious for angiomyolipoma with signs of progressive bleeding&#46; Given our suspicion of a retroperitoneal tumor lesion and the difficulty in characterizing the lesion&#44; abdominal magnetic resonance imaging &#40;MRI&#41; was performed&#44; revealing the presence of a large cystic mass initially interpreted as a retroperitoneal teratoma &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">In view of these findings&#44; it was decided to perform a left partial nephrectomy and excision of the large cystic mass&#46; A mixed tumor lesion with solid&#8211;cystic areas was macroscopically identified&#46; The definitive anatomopathological study identified a biphasic tumor made up of epithelial and stromal components &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">The patient is currently asymptomatic after 16 months of follow-up with no signs of recurrence or distant metastasis in subsequent imaging studies&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">MEST of the kidney is a rare entity of unknown etiology&#46; It accounts for about 0&#46;20&#37;&#8211;0&#46;28&#37; of all renal neoplasms and should be considered within the differential diagnosis of kidney tumors&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> It occurs most frequently in women aged between 36&#8211;80 &#40;mean age 46 years&#44; female&#58;male ratio of 6&#58;1<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a>&#41;&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">Although it is usually benign without recurrence or metastasis&#44;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> some cases of malignant sarcomatoid or carcinomatoid behavior have been described<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5&#44;6</span></a> and malignant transformation can be observed in both components&#58; the epithelial and the stromal&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">In cases with clinical manifestation&#44; it usually presents as a palpable abdominal mass&#44; macroscopic hematuria&#44; lumbar pain or urinary tract infection&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> However&#44; approximately 25&#37; of MEST are asymptomatic and diagnosed incidentally&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0040" class="elsevierStylePara elsevierViewall">The diagnosis is often based on the CT imaging diagnostic tool&#44; where it presents a diverse appearance&#59; it may sometimes mimic cystic nephroma and multilocular cystic renal cell carcinoma&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a></p><p id="par0045" class="elsevierStylePara elsevierViewall">Due to the difficulty to establish an accurate preoperative diagnosis of MEST in the absence of typical radiological features&#44;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> histopathological and immunohistochemical examination is mandatory to obtain a definitive postoperative diagnosis&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">Macroscopically&#44; it is a complex neoplasm composed of a mixture of solid and cystic elements&#44;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> well circumscribed&#44; with a size that ranges from a few centimeters to large masses&#46; In terms of histopathologic features&#44; they reveal a biphasic growth pattern comprising stromal elements with epithelial components&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">The immunohistochemical profile of the stromal component demonstrates positivity for desmin&#44; vimentin&#44; smooth muscle actin&#44; caldesmon&#44; estrogen and progesterone receptors&#44; as well as CD10&#46; The expression of estrogen and progesterone receptors in the stromal component reflects the influence of hormones in the development of this type of tumor&#46; The epithelial component usually expresses cytokeratins &#40;especially CK7&#41;&#44; GATA3 and PAX8&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">When feasible&#44; nephron-sparing surgery<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> is the standard treatment and these tumors have a favorable prognosis&#46;</p><p id="par0065" class="elsevierStylePara elsevierViewall">Since certain cases with malignant behavior have been described&#44; continuous postoperative follow-up<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> may be advisable in order to rule out possible malignant transformations in a subset of these patients&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Mart&#237;nez-Corral ME&#44; N&#250;&#241;ez-Otero JJ&#44; Toucedo-Caama&#241;o V&#44; Garc&#237;a-Acu&#241;a SM&#44; Garc&#237;a-Figueiras R&#44; Garc&#237;a-Freire C&#46; Tumor mixto epitelialestromal renal&#46; Actas Urol Esp&#46; 2021&#59;45&#58;412&#8211;415&#46;</p>"
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                            2 => "A&#46; Lopez-Beltran"
                            3 => "G&#46; Martignoni"
                            4 => "L&#46; Cheng"
                            5 => "F&#46; Montorsi"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Eur Urol"
                        "fecha" => "2008"
                        "volumen" => "54"
                        "paginaInicial" => "1237"
                        "paginaFinal" => "1246"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mixed epithelial and stromal tumor of the kidney"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "N&#46;V&#46; Adsay"
                            1 => "J&#46;N&#46; Eble"
                            2 => "J&#46;R&#46; Srigley"
                            3 => "E&#46;C&#46; Jones"
                            4 => "D&#46;J&#46; Grignon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/00000478-200007000-00007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "2000"
                        "volumen" => "24"
                        "paginaInicial" => "958"
                        "paginaFinal" => "970"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10895818"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pathology and genetics of tumours of the urinary system and male genital organs"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "J&#46;N&#46; Eble"
                            1 => "G&#46; Sauter"
                            2 => "J&#46;I&#46; Epstein"
                            3 => "I&#46;A&#46; Sesterhenn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "LibroEditado" => array:5 [
                        "editores" => "J&#46;N&#46;Eble, G&#46;Sauter, J&#46;I&#46;Epstein, I&#46;A&#46;Sesterhenn"
                        "titulo" => "World Health Organization classification of tumours"
                        "paginaInicial" => "77"
                        "paginaFinal" => "78"
                        "serieFecha" => "2004"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Malignant mixed epithelial and stromal tumor of the kidney&#58; report of the first male case"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "T&#46; Suzuki"
                            1 => "S&#46; Hiragata"
                            2 => "K&#46; Hosaka"
                            3 => "T&#46; Oyama"
                            4 => "N&#46; Kuroda"
                            5 => "O&#46; Hes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1111/j.1442-2042.2012.03155.x"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Urol"
                        "fecha" => "2013"
                        "volumen" => "20"
                        "paginaInicial" => "448"
                        "paginaFinal" => "450"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22989206"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mixed epithelial and stromal tumor of the kidney"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "B&#46;P&#46; Portier"
                            1 => "D&#46;E&#46; Hansel"
                            2 => "M&#46; Zhou"
                            3 => "G&#46;T&#46; Maclennan"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.juro.2009.01.004"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Urol"
                        "fecha" => "2009"
                        "volumen" => "181"
                        "paginaInicial" => "1879"
                        "paginaFinal" => "1880"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19233412"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "8"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mixed epithelial and stromal tumor of the kidney&#58; radiologic-pathologic correlation"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "L&#46;C&#46; Chu"
                            1 => "R&#46;H&#46; Hruban"
                            2 => "K&#46;M&#46; Horton"
                            3 => "E&#46;K&#46; Fishman"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1148/rg.306105503"
                      "Revista" => array:6 [
                        "tituloSerie" => "RadioGraphics"
                        "fecha" => "2010"
                        "volumen" => "30"
                        "paginaInicial" => "1541"
                        "paginaFinal" => "1551"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21071374"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "9"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adult mesoblastic nephroma&#58; expansion of the morphologic spectrum and review of literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "L&#46;D&#46; Truong"
                            1 => "R&#46; Williams"
                            2 => "T&#46; Ngo"
                            3 => "C&#46; Cawood"
                            4 => "P&#46; Chevez-Barrios"
                            5 => "H&#46;L&#46; Awalt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1097/00000478-199807000-00005"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Surg Pathol"
                        "fecha" => "1998"
                        "volumen" => "22"
                        "paginaInicial" => "827"
                        "paginaFinal" => "839"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9669345"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Adult cystic nephroma and mixed epithelial and stromal tumor of the kidney&#58; clinical&#44; radiographic&#44; and pathologic characteristics"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "B&#46;R&#46; Lane"
                            1 => "S&#46;C&#46; Campbell"
                            2 => "E&#46;M&#46; Remer"
                            3 => "A&#46;F&#46; Fergany"
                            4 => "S&#46;B&#46; Williams"
                            5 => "A&#46;C&#46; Novick"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:3 [
                        "tituloSerie" => "Urology"
                        "fecha" => "2008"
                        "volumen" => "71"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
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Original language: English
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