was read the article
array:18 [ "pii" => "13013603" "issn" => "03010546" "estado" => "S300" "fechaPublicacion" => "2001-03-01" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Allergol Immunopathol (Madr). 2001;29:45-6" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1534 "formatos" => array:3 [ "EPUB" => 11 "HTML" => 1307 "PDF" => 216 ] ] "itemSiguiente" => array:15 [ "pii" => "13013604" "issn" => "03010546" "estado" => "S300" "fechaPublicacion" => "2001-03-01" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Allergol Immunopathol (Madr). 2001;29:47-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2055 "formatos" => array:3 [ "EPUB" => 4 "HTML" => 1776 "PDF" => 275 ] ] "es" => array:9 [ "idiomaDefecto" => true "titulo" => "Diagnóstico de la alergia alimentaria: una prueba de paciencia" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "47" "paginaFinal" => "49" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Diagnosing food allergy: a test of patience" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "F Muñoz-López" "autores" => array:1 [ 0 => array:2 [ "Iniciales" => "F" "apellidos" => "Muñoz-López" ] ] ] ] ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13013604?idApp=UINPBA00004N" "url" => "/03010546/0000002900000002/v0_201402051322/13013604/v0_201402051322/es/main.assets" ] "en" => array:10 [ "idiomaDefecto" => true "titulo" => "Diagnosing food allergy: a test of patience" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "45" "paginaFinal" => "46" ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "F Muñoz-López" "autores" => array:1 [ 0 => array:2 [ "Iniciales" => "F" "apellidos" => "Muñoz-López" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Diagnóstico de la alergia alimentaria: una prueba de paciencia" ] ] "textoCompleto" => "<p class="elsevierStylePara"> Food-induced allergic reactions are one of the greatest problems faced by the clinician who in each case must establish whether the reaction is idiosyncratic, due to food poisoning, or anaphylactic. When the latter is suspected, allergists must arm themselves with patience to identify the food or the component of prepared food (spices or other condiments; additives) causing the reaction and must also be able to count on the patience of the patient who, more than ever, must bear with the clinician. The variety of foods, the lack of knowledge of the allergenic components of many of these foods, the modifications they may undergo during preparation (heating, boiling, maceration, etc.) are some of the reasons which make the identification of the causative agent of a suspected allergic reaction difficult. These difficulties are avoided only in lactating infants with hypersensitivity reactions to milk or egg, the most common and readily-suspected of allergic reactions. </p><p class="elsevierStylePara"> What diagnostic tests are available? Firstly, skin tests, using the skin prick test. A positive result may guide diagnosis but this happens in only a small percentage of cases, less than 40 %. This percentage may be higher when using milk- or egg-proteins. Although extracts of other foods are available, for many reasons they are not always of high quality (1). The prick-by-prick technique, may be useful with some foods. Majamaa et al (2) have reported a higher percentage of positive results when using a patch test in lactating infants to diagnose allergy to cow's milk. </p><p class="elsevierStylePara"> Another technique is testing for specific IgE (RAST or CAP). As with skin tests, a positive result guarantees that the reaction is allergic. In certain cases this may be sufficient to make a diagnosis provided that the clinical manifestations support a diagnosis of allergic reaction, or the risk of severe reaction by the food challenge is high (3). As with skin tests, the quality of the extracts plays an important role in the result of the serum reagin evaluation and consequently the proportion of positive results is not very high. For the same reason, published estimations of the sensitivity and specificity of both tests are very variables. </p><p class="elsevierStylePara"> When clinical symptomatology is prolonged (generally skin lesions), exclusion diets are a well-established diagnostic method that requires the close collaboration of the patient, or in the case of children, of the patient's parents. This method also demands a great deal of patience since the composition of all ingested foodstuffs must be closely monitored. Exclusion diets may be followed by open challenge with the suspected food, a positive result demonstrating that the food is responsible for the patient's symptomatology. After a period of exclusion, repetition of open challenge during follow-up may be useful to test for possible long-term tolerance. In this edition of Allergologia et Immunopathologia, Plaza et al. report their experience in this matter (4). </p><p class="elsevierStylePara"> The double-blind placebo-controlled food challenge is considered the gold-standard and is recommended to confirm diagnosis. Like exclusion diets, this test confirms only food intolerance and not an immuno-allergic mechanism; consequently, it should be complemented by skin tests and tests for specific IgE in serum (5). Plaut (6) reported that only 30-40 % of suspected food allergies were confirmed by this challenge test. Furthermore, this test is contraindicated in patients who have experienced serious manifestations, such as anaphylactic shock or other intense ractions (e.g. angioedema). </p><p class="elsevierStylePara"> In addition to the above-mentioned points, doubt remains on how food allergy should be diagnosed in daily clinical practice. A study by Kaila et al (7) reported that several methods were used in 24 Finnish clinics; although skin tests and specific IgE tests were carried out in all patients, various criteria were used in the performance of challenges. These findings could reflect the situation in other countries. The authors concluded that protocols should be established to standardize diagnostic methodology and, by way of example, cited the work of Niggeman et al (8), which was based on oral challenge. </p><p class="elsevierStylePara"> Given the frequency of allergic reactions to egg proteins in children, the Food Allergy Committee of the Spanish Society of Pediatric Clinical Immunolgy and Allergy have drawn up a position paper, which provides a practical review of the problems caused by sensitization to this common food, including diagnostic methodology and egg exclusion diets. This paper is published in the current edition of Allergologia et Immunopathologia (9). </p>" "pdfFichero" => "105v29n02a13013603pdf001.pdf" "tienePdf" => true "bibliografia" => array:2 [ "titulo" => "Bibliography" "seccion" => array:1 [ 0 => array:1 [ "bibliografiaReferencia" => array:9 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "referenciaCompleta" => "Factors influencing the quality of food extracts for in vitro and in vivodiagnosis. Allergy 1998; (Suppl. 46) 53: 65-71." "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "Vieths S" 1 => "Hoffmann A" 2 => "Hotzhauser T" 3 => "Müller U" 4 => "Reindl J" 5 => "Haustein D." ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:3 [ "titulo" => "Cow's milk allergy: diagnostic accuracy of skin prick and patch tests and specific IgE." "idioma" => "en" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "Majamaa H" 1 => "Moisio P" 2 => "Holm K" 3 => "Kautiainen H" 4 => "Turjanmaa K." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Allergy" "fecha" => "1999" "volumen" => "54" "paginaInicial" => "346" "paginaFinal" => "51" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10371093" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib3" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:3 [ "titulo" => "Relationship between food-specific IgE concentrations and the risk of positive food challenges in children and adolescents." "idioma" => "en" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "Sampson HA" 1 => "Ho DG." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "J Allergy Clin Immunol" "fecha" => "1997" "volumen" => "100" "paginaInicial" => "444" "paginaFinal" => "51" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9338535" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib4" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "referenciaCompleta" => "Challenge testing in children with cow milk-protein allergy. Allergol et Immunopathol 2001; 29 (2): 50-54." "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "Plaza AM" 1 => "Martín Mateos MA" 2 => "Giner Muñoz MT" 3 => "Sierra JI." ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib5" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "referenciaCompleta" => "Food allergy and intolerance. Cap. 15 En: Ph. Liberman and JA. Anderson (edts.) Allergic diseases. Diagnosis and treatment. 2nd ed. Human Press, Totoya, NY., 2000." "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "Anderson JA." ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib6" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:3 [ "titulo" => "New directions in food allergy research." "idioma" => "en" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "Plaut M." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "J Allegy Clin Immunol" "fecha" => "1997" "volumen" => "100" "paginaInicial" => "7" "paginaFinal" => "10" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib7" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:3 [ "titulo" => "Diagnosis of food allergy in Finland: survey of pediatric practices." "idioma" => "en" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "Kaila M" 1 => "Vanto T" 2 => "Valovirta E" 3 => "Koivikko A" 4 => "Juntunen-Backman K." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatr Allergy Immunol" "fecha" => "2000" "volumen" => "11" "paginaInicial" => "246" "paginaFinal" => "9" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11110580" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib8" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:3 [ "titulo" => "Proposal for standardization of oral food challenge tests in infants and children." "idioma" => "en" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "Niggeman B" 1 => "Wahn U" 2 => "Sampson HA." ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Pediatr Allergy Immunol" "fecha" => "1994" "volumen" => "5" "paginaInicial" => "11" "paginaFinal" => "13" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8173633" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib9" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "referenciaCompleta" => "Allergy to egg proteins. Food Allergy Committee of the Spanish Society of Pediatric Clinical Immunology and Allergy. Allergol et Immunopathol 2001; 29 (2): 72-83." "contribucion" => array:1 [ 0 => array:1 [ "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "Martorell A" 1 => "Boné J" 2 => "García Ara MC" 3 => "Nevot S" 4 => "Plaza AM." ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/03010546/0000002900000002/v0_201402051322/13013603/v0_201402051322/en/main.assets" "Apartado" => array:4 [ "identificador" => "6701" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Editorial" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/03010546/0000002900000002/v0_201402051322/13013603/v0_201402051322/en/105v29n02a13013603pdf001.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/13013603?idApp=UINPBA00004N" ]
Original language: English
Year/Month | Html | Total | |
---|---|---|---|
2024 October | 14 | 4 | 18 |
2024 September | 17 | 2 | 19 |
2024 August | 15 | 6 | 21 |
2024 July | 22 | 7 | 29 |
2024 June | 15 | 8 | 23 |
2024 May | 9 | 3 | 12 |
2024 April | 14 | 4 | 18 |
2024 March | 21 | 6 | 27 |
2024 February | 28 | 6 | 34 |
2024 January | 31 | 9 | 40 |
2023 December | 10 | 7 | 17 |
2023 November | 20 | 6 | 26 |
2023 October | 21 | 7 | 28 |
2023 September | 13 | 2 | 15 |
2023 August | 13 | 9 | 22 |
2023 July | 13 | 2 | 15 |
2023 June | 19 | 7 | 26 |
2023 May | 24 | 2 | 26 |
2023 April | 16 | 5 | 21 |
2023 March | 19 | 5 | 24 |
2023 February | 21 | 1 | 22 |
2023 January | 11 | 5 | 16 |
2022 December | 11 | 5 | 16 |
2022 November | 27 | 5 | 32 |
2022 October | 11 | 10 | 21 |
2022 September | 22 | 8 | 30 |
2022 August | 14 | 8 | 22 |
2022 July | 10 | 13 | 23 |
2022 June | 9 | 9 | 18 |
2022 May | 14 | 17 | 31 |
2022 April | 10 | 11 | 21 |
2022 March | 11 | 13 | 24 |
2022 February | 11 | 7 | 18 |
2022 January | 15 | 11 | 26 |
2021 December | 9 | 14 | 23 |
2021 November | 10 | 10 | 20 |
2021 October | 15 | 23 | 38 |
2021 September | 12 | 12 | 24 |
2021 August | 9 | 8 | 17 |
2021 July | 9 | 10 | 19 |
2021 June | 10 | 14 | 24 |
2021 May | 12 | 7 | 19 |
2021 April | 24 | 23 | 47 |
2021 March | 13 | 12 | 25 |
2021 February | 11 | 9 | 20 |
2021 January | 16 | 9 | 25 |
2020 December | 1 | 0 | 1 |
2018 February | 2 | 0 | 2 |
2018 January | 4 | 0 | 4 |
2017 December | 1 | 0 | 1 |
2017 November | 4 | 1 | 5 |
2017 October | 4 | 0 | 4 |
2017 September | 7 | 2 | 9 |
2017 August | 8 | 4 | 12 |
2017 July | 7 | 4 | 11 |
2017 June | 10 | 1 | 11 |
2017 May | 11 | 2 | 13 |
2017 April | 14 | 0 | 14 |
2017 March | 7 | 1 | 8 |
2017 February | 15 | 0 | 15 |
2017 January | 17 | 0 | 17 |
2016 December | 25 | 4 | 29 |
2016 November | 21 | 2 | 23 |
2016 October | 17 | 2 | 19 |
2016 September | 14 | 4 | 18 |
2016 August | 8 | 1 | 9 |
2016 July | 7 | 2 | 9 |
2016 June | 11 | 6 | 17 |
2016 May | 18 | 2 | 20 |
2016 April | 9 | 9 | 18 |
2016 March | 12 | 7 | 19 |
2016 February | 13 | 9 | 22 |
2016 January | 10 | 10 | 20 |
2015 December | 12 | 5 | 17 |
2015 November | 13 | 4 | 17 |
2015 October | 9 | 4 | 13 |
2015 September | 9 | 4 | 13 |
2015 August | 10 | 1 | 11 |
2015 July | 6 | 2 | 8 |
2015 June | 2 | 0 | 2 |
2015 May | 3 | 1 | 4 |
2015 April | 9 | 3 | 12 |
2015 March | 6 | 7 | 13 |
2015 February | 6 | 0 | 6 |
2015 January | 21 | 9 | 30 |
2014 December | 31 | 6 | 37 |
2014 November | 11 | 3 | 14 |
2014 October | 23 | 4 | 27 |
2014 September | 24 | 2 | 26 |
2014 August | 13 | 5 | 18 |
2014 July | 8 | 1 | 9 |
2014 June | 12 | 0 | 12 |
2014 May | 10 | 1 | 11 |
2014 April | 5 | 1 | 6 |
2014 March | 19 | 9 | 28 |
2014 February | 23 | 6 | 29 |
2014 January | 19 | 2 | 21 |
2013 December | 18 | 7 | 25 |
2013 November | 17 | 7 | 24 |
2013 October | 22 | 7 | 29 |
2013 September | 22 | 6 | 28 |
2013 August | 31 | 4 | 35 |
2013 July | 21 | 3 | 24 |
2013 June | 8 | 3 | 11 |
2013 May | 20 | 6 | 26 |
2013 April | 17 | 12 | 29 |
2013 March | 4 | 4 | 8 |
2013 February | 1 | 1 | 2 |
2013 January | 0 | 1 | 1 |
2012 December | 0 | 1 | 1 |
2012 November | 2 | 1 | 3 |
2001 March | 544 | 0 | 544 |