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Grande-Martín, J.M. Pardal-Fernández" "autores" => array:2 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Grande-Martín" ] 1 => array:2 [ "nombre" => "J.M." 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González-López, C. Fuente García, F.J. Muñoz-Negrete, G. Rebolleda" "autores" => array:4 [ 0 => array:4 [ "nombre" => "J.J." "apellidos" => "González-López" "email" => array:1 [ 0 => "juliojose.gonzalez@live.com" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "C." "apellidos" => "Fuente García" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "F.J." "apellidos" => "Muñoz-Negrete" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "G." "apellidos" => "Rebolleda" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Oftalmología, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Madrid, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Cirugía, Ciencias Médicas y Sociales, Universidad de Alcalá de Henares, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Respuesta de los autores" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We are grateful for the interest shown in our review. We agree that the negative electroretinogram could include cases in which the <span class="elsevierStyleItalic">a</span> wave is diminished and in fact the definition of <span class="elsevierStyleItalic">b</span>/<span class="elsevierStyleItalic">a</span> < 1 is that indicated in said review.</p><p id="par0010" class="elsevierStylePara elsevierViewall">It is true that for patients associating neurodegeneration clinic who exhibit said electroretinographic finding we should include lipopigment aggregation diseases such as ceroid-lipofuscinosis (Batten's disease), mucolipidosis IV and Refsum disease in the differential diagnostic, taking into account the low prevalence of said diseases within the negative ERG causes.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">It is worthwhile pointing out that, in the clinic practice study by Koh et al.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a>, all the ERG negative cases in patients with retinal photoreceptor dystrophies (rods-cones, cones-rods or cones), the response associated significant <span class="elsevierStyleItalic">a</span> wage reduction. Being a more frequent finding in electroretinographic response than the strictly negative response (<span class="elsevierStyleItalic">b</span>/<span class="elsevierStyleItalic">a</span> < 1 with wave <span class="elsevierStyleItalic">a</span> having normal amplitude), the specificity thereof diminishes. Accordingly, in clinic practice and when preparing differential diagnostic, it is advisable to differentiate between a strictly negative response (<span class="elsevierStyleItalic">b</span>/<span class="elsevierStyleItalic">a</span> < 1 with normal amplitude wave <span class="elsevierStyleItalic">a</span> which is more useful to define the differential diagnostic) and a negative response with diminished wave <span class="elsevierStyleItalic">a</span>, which is more unspecific.</p><p id="par0020" class="elsevierStylePara elsevierViewall">We also wish to thank the readers who have identified the error related to the Schubert-Bornschein disease. The complete response indicates loss of the ON pathway with preservation of the OFF pathway,<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a> whereas the incomplete response indicates and involvement of the ON and OFF pathways.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a></p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: González-López JJ, Fuente García C, Muñoz-Negrete FJ, Rebolleda G. Respuesta de los autores. Arch Soc Esp Oftalmol. 2018;93:e47–e47.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0020" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The incidence of negative ERG in clinical practice" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "A.H. Koh" 1 => "C.R. Hogg" 2 => "G.E. Holder" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Doc Ophthalmol" "fecha" => "2001" "volumen" => "102" "paginaInicial" => "19" "paginaFinal" => "30" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11475363" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0025" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Scotopic threshold response in complete and incomplete types of congenital stationary night blindness" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "Y. Miyake" 1 => "M. Horiguchi" 2 => "H. Terasaki" 3 => "M. 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Journal Information
Vol. 93. Issue 7.
Pages e47 (July 2018)
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