Intraoperative floppy iris syndrome after treatment with duloxetine: Coincidence, association, or causality?

Abstract

Case report

The case is presented of a severe intraoperative floppy iris syndrome (IFIS) in a patient that had been treated with duloxetine.

Discussion

Tamsulosin is the main etiological agent involved in IFIS. However several cases of IFIS, supposedly secondary to drugs of different groups, have recently been reported in the literature. The authors use this case report as a means to discuss why most of these cases should be considered anecdotal evidence.

Resumen

Caso clínico

Se presenta un caso de síndrome de iris flácido intraoperatorio (IFIS) severo en una paciente que había recibido tratamiento con duloxetina.

Discusión

Aunque el agente etiológico principal es la tamsulosina, se han descrito casos de IFIS supuestamente secundarios a fármacos pertenecientes a diversos grupos farmacológicos. Los autores utilizan este caso para realizar un análisis crítico de todas estas asociaciones anecdóticas comunicadas en la literatura.