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Inicio Archivos de la Sociedad Española de Oftalmología (English Edition) Parinaud “plus” syndrome in a patient with dysgerminoma
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Vol. 91. Issue 7.
Pages 341-345 (July 2016)
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Vol. 91. Issue 7.
Pages 341-345 (July 2016)
Short communication
Parinaud “plus” syndrome in a patient with dysgerminoma
Síndrome de Parinaud «plus» en paciente con disgerminoma
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385
C. Burgueño-Montañésa,
Corresponding author
casamata@gmail.com

Corresponding author.
, C. Santalla-Castroa, J. Peña-Suárezb
a Servicio de Oftalmología, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
b Servicio de Radiodiagnóstico, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
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Abstract
Clinical case

A 33-year-old male diagnosed with Parinaud's syndrome, exotropia and post-papillary oedema optic atrophy in his left eye. A pineal germinoma was diagnosed after performing neuroimaging scans and a stereotactic biopsy. He was treated with chemotherapy and radiotherapy, showing a complete pathological response. The Parinaud's syndrome persists one year after diagnosis and the patient has refused to have strabismus surgery.

Discussion

Parinaud's syndrome consists of a supranuclear vertical gaze palsy resulting from damage to the midbrain tectum. The involvement of adjacent structures leads to the “Parinaud-plus” syndrome. When a Parinaud's syndrome is accompanied by diplopia (“Parinaud-plus” syndrome), extension of the injury into adjacent areas must be considered.

Keywords:
Parinaud's syndrome
Dorsal midbrain syndrome
Germinoma
Dysgerminoma
Pineal tumours
Resumen
Caso clínico

Varón de 33 años con síndrome de Parinaud, exotropía y atrofia óptica del OI postpapiledema. Tras las pruebas de neuroimagen y biopsia estereotáxica se diagnostica de germinoma pineal. Recibe quimio y radioterapia con respuesta completa del tumour. El síndrome de Parinaud persiste un año después del diagnóstico, y rechaza la corrección del estrabismo.

Discusión

El síndrome de Parinaud consiste en una parálisis supranuclear de la mirada vertical por daño del tectum mesencefálico. El compromiso de las estructuras adyacentes da lugar al síndrome de Parinaud «plus». Ante un síndrome de Parinaud acompañado de diplopía (síndrome de Parinaud «plus») se debe pensar en la extensión de la lesión a otras áreas adyacentes.

Palabras clave:
Síndrome de Parinaud
Síndrome mesencefálico dorsal
Germinoma
Disgerminoma
Tumores pineales

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