Share
array:24 [ "pii" => "S2173579420300190" "issn" => "21735794" "doi" => "10.1016/j.oftale.2019.12.003" "estado" => "S300" "fechaPublicacion" => "2020-03-01" "aid" => "1611" "copyright" => "Sociedad Española de Oftalmología" "copyrightAnyo" => "2020" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2020;95:141-5" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0365669120300034" "issn" => "03656691" "doi" => "10.1016/j.oftal.2019.12.007" "estado" => "S300" "fechaPublicacion" => "2020-03-01" "aid" => "1611" "copyright" => "Sociedad Española de Oftalmología" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2020;95:141-5" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "es" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Comunicación corta</span>" "titulo" => "Coriorretinopatía serosa central bilateral y multifocal después de inyectar triamcinolona en un chalazión" "tienePdf" => "es" "tieneTextoCompleto" => "es" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "141" "paginaFinal" => "145" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Bilateral and multifocal central serous chorioretinopathy after injecting triamcinolone into a chalazion" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figura 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 535 "Ancho" => 955 "Tamanyo" => 109028 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">La OCT mostró resolución del líquido subretiniano y de los DEP. OD (A) y OI (B): mismo corte que el mostrado en la <a class="elsevierStyleCrossRef" href="#fig0005">figura 1</a>C.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "V.M. Asensio-Sánchez, L. Pareja-Aricó, J. Valentín-Bravo" "autores" => array:3 [ 0 => array:2 [ "nombre" => "V.M." "apellidos" => "Asensio-Sánchez" ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Pareja-Aricó" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Valentín-Bravo" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2173579420300190" "doi" => "10.1016/j.oftale.2019.12.003" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579420300190?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669120300034?idApp=UINPBA00004N" "url" => "/03656691/0000009500000003/v2_202108150630/S0365669120300034/v2_202108150630/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2173579420300177" "issn" => "21735794" "doi" => "10.1016/j.oftale.2019.11.008" "estado" => "S300" "fechaPublicacion" => "2020-03-01" "aid" => "1605" "copyright" => "Sociedad Española de Oftalmología" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2020;95:146-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "Use of ganglion cell layer analysis for diagnosing anti-glycoprotein neuromyelitis optica of oligodendrocyte myelin" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "146" "paginaFinal" => "149" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Uso del análisis de la capa de células ganglionares para el diagnóstico en la neuromielitis óptica anti-glucoproteína de la mielina del oligodendrocito" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 583 "Ancho" => 1874 "Tamanyo" => 136692 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">cerebral NMR. A) coronal sequence. B) axial sequence. C) FLAIR and axial reconstruction axial of T1 3D with gadolinium, showing broad anomaly with thickening. T2 hyperintensity and patched highlighting along the left optic nerve (white arrows) and in the optic chiasma and optical pathways (blue arrows).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Cerveró, M.J. Sedano-Tous, J. Madera, A. López-de-Eguileta, A. Casado" "autores" => array:5 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Cerveró" ] 1 => array:2 [ "nombre" => "M.J." "apellidos" => "Sedano-Tous" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Madera" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "López-de-Eguileta" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Casado" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0365669119303570" "doi" => "10.1016/j.oftal.2019.11.011" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669119303570?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579420300177?idApp=UINPBA00004N" "url" => "/21735794/0000009500000003/v1_202002280728/S2173579420300177/v1_202002280728/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2173579420300189" "issn" => "21735794" "doi" => "10.1016/j.oftale.2020.01.001" "estado" => "S300" "fechaPublicacion" => "2020-03-01" "aid" => "1621" "copyright" => "Sociedad Española de Oftalmología" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2020;95:138-40" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "Use of semisynthetic dura mater substitute as a patch graft for prosthesis extrusion in anophthalmic socket" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "138" "paginaFinal" => "140" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Uso de sustituto semisintético de duramadre como injerto tras extrusión de prótesis en una cavidad anoftálmica" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 846 "Ancho" => 1310 "Tamanyo" => 107226 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A. Magnetic resonance (T2) showing a single intraocular mass in the left eye associated to retinal detachment and no extraocular involvement. B. Fundus imaging showing the tumor and retinal detachment. C. Tumor regression with a calcified pattern <span class="elsevierStyleItalic">(white arrow)</span> and multiple new lesions in middle periphery <span class="elsevierStyleItalic">(white arrow heads)</span>.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "M. Rahhal-Ortuño, A.S. Fernández-Santodomingo, H. Barranco-González, I. Almor-Palacios, A. Rodrigo-Hernández, J. Vila-Arteaga" "autores" => array:6 [ 0 => array:2 [ "nombre" => "M." "apellidos" => "Rahhal-Ortuño" ] 1 => array:2 [ "nombre" => "A.S." "apellidos" => "Fernández-Santodomingo" ] 2 => array:2 [ "nombre" => "H." "apellidos" => "Barranco-González" ] 3 => array:2 [ "nombre" => "I." "apellidos" => "Almor-Palacios" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Rodrigo-Hernández" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Vila-Arteaga" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0365669120300289" "doi" => "10.1016/j.oftal.2020.01.005" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669120300289?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579420300189?idApp=UINPBA00004N" "url" => "/21735794/0000009500000003/v1_202002280728/S2173579420300189/v1_202002280728/en/main.assets" ] "en" => array:20 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "Bilateral and multifocal central serous chorioretinopathy after injecting triamcinolone into a chalazion" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "141" "paginaFinal" => "145" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "V.M. Asensio-Sánchez, L. Pareja-Aricó, J. Valentín-Bravo" "autores" => array:3 [ 0 => array:4 [ "nombre" => "V.M." "apellidos" => "Asensio-Sánchez" "email" => array:2 [ 0 => "victor_asensio@orangemail.es" 1 => "vmasensio@yahoo.es" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "L." "apellidos" => "Pareja-Aricó" ] 2 => array:2 [ "nombre" => "J." "apellidos" => "Valentín-Bravo" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Hospital Clínico Universitario de Valladolid, Valladolid, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Coriorretinopatía serosa central bilateral y multifocal después de inyectar triamcinolona en un chalazión" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 535 "Ancho" => 955 "Tamanyo" => 109028 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">OCT shows resolution of the subretinal fluid and RPED. RE (A) and LE (B): same section as shown in <a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Central serous chorioretinopathy is an idiopathic, frequently bilateral, asymmetric and in many cases recurring disease characterized by serous retinal detachment and/or retinal pigment epithelium detachment (RPED)1. It occurs more frequently in healthy middle-aged men and is associated to loss of fluid through the retina pigment epithelium towards the subretinal space.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> The most consistent etiology of central serous chorioretinopathy (CSC) is the use of corticoids.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2,3</span></a> The case of a patient who developed bilateral and multifocal CSC after injecting triamcinolone acetonide in a chalazion is described.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Clinic case</span><p id="par0010" class="elsevierStylePara elsevierViewall">Male, 58, without relevant systemic antecedents. Ophthalmologically, the patient had a record of blepharitis with multiple repeated styes treated on various occasions with heat and antibiotic creams. He visited due to chalazion with 5 months evolution in the upper left eyelid. It was decided to inject 0.5<span class="elsevierStyleHsp" style=""></span>ml of triamcinolone acetonide (Trigon Depot 40<span class="elsevierStyleHsp" style=""></span>mg/ml, Bristol-Myers Squibb, S.A., Madrid, Spain) in the chalazion. Two weeks later the patient visited referring poor vision in both eyes (BE) seeing everything «like through a roughly polished glass», particularly with the left eye (LE). Examination produced a visual acuity of 0.7 in the right eye RE) and 0.5 in the LE. Intraocular pressure was 18<span class="elsevierStyleHsp" style=""></span>mmHg in BE. The RE fundus showed a small RPED nasally from the macula (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a> A left). The LE fundus exhibited a retinal raising with clear fluid occupying a large part of the macula (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A right). Fluorescein angiography showed 3 hyperfluorescence areas in the LE corresponding to RPED; the lower one was under the raised area and lost contrast (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). The RE showed a hyperfluorescence dot that extended to fill in the RPED which remained unchanged (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Autofluorescence showed an increase in the LE neurosensory raising area, with clear anatomical correspondence with the retinography and hyperfluorescence areas in BE matching the angiographic loss areas (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B). OCT revealed several RPED and a small one associated to the neuroepithelium detachment in the LE (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C). It was decided to maintain observation and 3 months later vision was 0.9 in BE without central scotoma perception. OCT showed resolution of the subretinal fluid and of the RPED (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Discussion</span><p id="par0015" class="elsevierStylePara elsevierViewall">Due to clinic history and findings, the patient was diagnosed with bilateral and multifocal CSC, probably due to the use of triamcinolone injected in the chalazion. Corticosteroids are utilized for treating a broad range of processes or suppressing inflammatory and allergic disorders. They exhibit easily recognizable side effects including gastrointestinal and psychiatric effects although CSC is rare and could go unnoticed. CSC is a disease presenting serous retinal detachment frequently associated to RPED.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> In general, CSC affects young and middle-aged adults, more frequently males. It has been found that CSC is associated to psychological stress and type A personality although its etiology seems to be multifactorial, including the use of exogenous steroids, endogenous hypercortisolism, <span class="elsevierStyleItalic">Helicobacter pylori</span> infection, hypertension, alcohol and psychoactive drugs.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a> However, cortisol increase is regarded as the most consistent etiology.<a class="elsevierStyleCrossRefs" href="#bib0010"><span class="elsevierStyleSup">2,3</span></a> High plasmatic cortisol increases the capillary permeability and fragility in the choriocapillary.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> Zhao et al.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> considered that the underlying mechanism is the activation of the mineral-corticoid receptor by glycocorticoids, which induce positive regulation of the KCa2,3 channel that leads to choroidal vasodilatation. CSC has been associated to the use of corticosteroids not only with systemic administration but also with local application pathways.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> However, CSC has rarely been described after the injection of intravitreal and periocular steroids. The current criteria for evaluating cortisol excess are controversial. There is no consensus on the most reliable clinic and biochemical elements to diagnose this process. The cortisol levels were not assessed in the present patient because the first level test is a sensitive and poorly specific cortisol in urine test, with a range between 10 and 110<span class="elsevierStyleHsp" style=""></span>μg/day. Accordingly, the clinic history and the identification of subtle signs play a crucial role for suspecting hypercortisolism in organs and systems. Corticoids with a limited time action do not prevent said side effects, as CSC has been described with the utilization of dexamethasone.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The authors believe that the use of triamcinolone not approved for ophthalmic use did not influence the etiopathogeny of the condition due to the fact that CSC has been described in triamcinolone preparations approved for intra-articular, intra-nasal, epidural and cutaneous use with the same active principle, i.e., triamcinolone acetonide. Any patient using steroids in any form should be informed about the possibility of developing CSC. Araki et al.<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> considered that CSC associated to steroids expresses in elderly patients without prevalence for males and with increased bilateral compromise, hardly any tobacco smoking history and a significantly high history of psychoactive drug use. Rosignoli et al.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> described the case of a patient that developed bilateral CSC one month after a triamcinolone injection during chalazion surgery, which evolved with impaired vision requiring photodynamic therapy. The patient described in the present article did not have a history of treatment with systemic or local steroids, was a non-smoker and did not use drugs against anxiety, although there was a timely association between the triamcinolone injection and the bilateral onset of CSC. Fluorescein angiography showed multiple leak points, including the fovea, as well as in several RPED. Three months after the injection the subretinal fluid and the RPED disappeared, for which reason observation should be the first choice in these cases. In the described patient the choroids was bilaterally thickened, which is an indirect validation of the proposed choroidal vascular hyperpermeability and indicates that this is part of the physiopathogeny of the disease.</p><p id="par0025" class="elsevierStylePara elsevierViewall">The authors were unable to find any reference in the literature establishing the period during which the relationship between the administration and the expression of CSC should be taken into account. However, the present patient presented a spontaneous resolution during the 3rd month. It is unlikely that the patient developed CSC for causes other than the steroid injection. The use of multimodal images enables a more precise diagnostic of the disorder by discarding other causes of serous retina detachment. In addition, it enables the determination of the chronic nature of the process and improves the ability to adapt treatments to each individual case. Fluorescein angiography, autofluorescence and OCT utilized in the present case revealed a unique picture of the clinic and provided a physiological perspective to determine the patient’s prognosis as well as the best targeting therapy. The prognostic of these patients is reserved due to the severity of the expressions that indicate diffuse damages in the retinal pigment epithelium, which could produce more frequent recurrences. Early identification and interruption of steroids treatments are necessary to diminish visual impairment, although it is important to emphasize the possible side effects of a measure as widespread as steroid injections for chalazion.</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conflict of interests</span><p id="par0030" class="elsevierStylePara elsevierViewall">No conflict of interests was declared by the authors.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:9 [ 0 => array:3 [ "identificador" => "xres1312672" "titulo" => "Abstract" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0005" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec1211551" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres1312671" "titulo" => "Resumen" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0010" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec1211550" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Clinic case" ] 6 => array:2 [ "identificador" => "sec0015" "titulo" => "Discussion" ] 7 => array:2 [ "identificador" => "sec0020" "titulo" => "Conflict of interests" ] 8 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2019-10-09" "fechaAceptado" => "2019-12-17" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec1211551" "palabras" => array:6 [ 0 => "Central serous chorioretinopathy" 1 => "Corticosteroid" 2 => "Bilateral" 3 => "Multifocal" 4 => "Triamcinolone" 5 => "Chalazion" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec1211550" "palabras" => array:6 [ 0 => "Coriorretinopatía serosa central" 1 => "Corticoide" 2 => "Bilateral" 3 => "Multifocal" 4 => "Triamcinolona" 5 => "Chalazión" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We present a case of bilateral and multifocal central serous chorioretinopathy (CSC) that developed 1 month after an intra-chalazion triamcinolone acetonide injection. CSC spontaneously resolved during observation at 3 months after diagnosis. We believe that CSC can occur as a complication of administration of depot corticosteroids even at a low dose.</p></span>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Se describe un caso de coriorretinopatía serosa central (CSC) bilateral y multifocal que se desarrolló 1 mes después de una inyección de acetónido de triamcinolona en un chalazión. La CSC se resolvió espontáneamente durante la observación a los 3 meses después del diagnóstico. Consideramos que la CSC puede ocurrir como una complicación de la administración de corticosteroides de depósito incluso a una dosis baja.</p></span>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Asensio-Sánchez VM, Pareja-Aricó L, Valentín-Bravo J. Coriorretinopatía serosa central bilateral y multifocal después de inyectar triamcinolona en un chalazión. Arch Soc Esp Oftalmol. 2020;95:141–145.</p>" ] ] "multimedia" => array:3 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2690 "Ancho" => 2508 "Tamanyo" => 381928 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">A. Left: RE retinograph showing fluid nasally from the fovea, corresponding to a small RPED. Right: LE retinograph showing whitish-orange decoloration of the macular region with associate subretinal fluid occupying most of the temporal macula. B. bilateral hypo-autofluorescence areas matching the leak points in the angiograph. C. LE OCT image corresponding to the area marked in yellow in <a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A right: discrete accumulation of fluid below the pigment epithelium, just nasally from the foveal depression. This defines the RPED. The overlying serous retina detachment is also evident. The yellow vertical line shows the subfoveal choroidal thickness (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article).</p>" ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 2942 "Ancho" => 2508 "Tamanyo" => 263709 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0010" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">LE fluorescein angiograph shows several leak points that remain unchanged (RPED); late images show the loss of contrast of the lower point, correlating with the clinic eye fundus shown in <a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A. RE angiogram shows the accumulation of contrast within the RPED.</p>" ] ] 2 => array:8 [ "identificador" => "fig0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 535 "Ancho" => 955 "Tamanyo" => 109028 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0015" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">OCT shows resolution of the subretinal fluid and RPED. RE (A) and LE (B): same section as shown in <a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Central serous chorioretinopathy: an update on pathogenesis and treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Gemenetzi" 1 => "G. De Salvo" 2 => "A.J. Lotery" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eye (Lond)" "fecha" => "2010" "volumen" => "24" "paginaInicial" => "1743" "paginaFinal" => "1756" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0010" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk factors for central serous chorioretinopathy: a case-control study" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Haimovici" 1 => "S. Koh" 2 => "D.R. Gagnon" 3 => "T. Lehrfeld" 4 => "S. Wellik" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.ophtha.2003.09.024" "Revista" => array:7 [ "tituloSerie" => "Ophthalmology" "fecha" => "2004" "volumen" => "111" "paginaInicial" => "244" "paginaFinal" => "249" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15019370" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S1474442215003221" "estado" => "S300" "issn" => "14744422" ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0015" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Systemic findings associated with central serous chorioretinopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M.K. Tittl" 1 => "R.F. Spaide" 2 => "D. Wong" 3 => "E. Pilotto" 4 => "L.A. Yannuzzi" 5 => "Y.L. Fisher" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/s0002-9394(99)00075-6" "Revista" => array:7 [ "tituloSerie" => "Am J Ophthalmol" "fecha" => "1999" "volumen" => "128" "paginaInicial" => "63" "paginaFinal" => "68" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10482095" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673612617693" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0020" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Central serous chorioretinopathy: update on pathophysiology and treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "B. Nicholson" 1 => "J. Noble" 2 => "F. Forooghian" 3 => "C. Meyerle" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.survophthal.2012.07.004" "Revista" => array:6 [ "tituloSerie" => "Surv Ophthalmol" "fecha" => "2013" "volumen" => "58" "paginaInicial" => "103" "paginaFinal" => "126" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23410821" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0025" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Risk factors for central serous chorioretinopathy: A systematic review and meta-analysis" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "B. Liu" 1 => "T. Deng" 2 => "J. Zhang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/IAE.0000000000000837" "Revista" => array:6 [ "tituloSerie" => "Retina" "fecha" => "2016" "volumen" => "36" "paginaInicial" => "9" "paginaFinal" => "19" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26710181" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0030" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Visual outcome after discontinuation of corticosteroids in atypical severe central serous chorioretinopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T. Sharma" 1 => "N. Shah" 2 => "M. Rao" 3 => "L. Gopal" 4 => "M.P. Shanmugam" 5 => "M. Gopalakrishnan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Ophthalmology" "fecha" => "2004" "volumen" => "11" "paginaInicial" => "1708" "paginaFinal" => "1714" ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0035" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Zhao" 1 => "I. Célérier" 2 => "E. Bousquet" 3 => "J.C. Jeanny" 4 => "L. Jonet" 5 => "M. Savoldelli" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1172/JCI61427" "Revista" => array:6 [ "tituloSerie" => "J Clin Invest" "fecha" => "2012" "volumen" => "122" "paginaInicial" => "2672" "paginaFinal" => "2679" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22684104" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0040" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Localized topical steroid use and central serous retinopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L.Y. Chan" 1 => "R.S. Adam" 2 => "D.N. Adam" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3109/09546634.2015.1136049" "Revista" => array:6 [ "tituloSerie" => "J Dermatolog Treat" "fecha" => "2016" "volumen" => "27" "paginaInicial" => "425" "paginaFinal" => "426" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/26822912" "web" => "Medline" ] ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0045" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Central serous chorioretinopathy with and without steroids: A multicenter survey" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "T. Araki" 1 => "H. Ishikawa" 2 => "C. Iwahashi" 3 => "M. Niki" 4 => "Y. Mitamura" 5 => "M. Sugimoto" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1371/journal.pone.0213110" "Revista" => array:5 [ "tituloSerie" => "PLoS One" "fecha" => "2019" "volumen" => "14" "paginaInicial" => "e0213110" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30818363" "web" => "Medline" ] ] ] ] ] ] ] ] 9 => array:3 [ "identificador" => "bib0050" "etiqueta" => "10" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Development of central serous chorioretinopathy following chalazion removal with intralesional triamcinolone injection: A Case Report" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "L. Rosignoli" 1 => "S.M. Potter" 2 => "A. Gonzalez" 3 => "S. Amin" 4 => "S.G. Khurshid" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1159/000492714" "Revista" => array:7 [ "tituloSerie" => "Case Rep Ophthalmol" "fecha" => "2018" "volumen" => "9" "paginaInicial" => "416" "paginaFinal" => "420" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/30323759" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0140673612617681" "estado" => "S300" "issn" => "01406736" ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735794/0000009500000003/v1_202002280728/S2173579420300190/v1_202002280728/en/main.assets" "Apartado" => array:4 [ "identificador" => "76120" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Shorts communications" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735794/0000009500000003/v1_202002280728/S2173579420300190/v1_202002280728/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579420300190?idApp=UINPBA00004N" ]
