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Abreu-González, M. Alberto-Pestano, G. Rubio-Rodríguez, P. Abreu Reyes" "autores" => array:4 [ 0 => array:4 [ "nombre" => "R." "apellidos" => "Abreu-González" "email" => array:1 [ 0 => "rodrigoabreug@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Alberto-Pestano" ] 2 => array:2 [ "nombre" => "G." "apellidos" => "Rubio-Rodríguez" ] 3 => array:2 [ "nombre" => "P." "apellidos" => "Abreu Reyes" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Oftalmología, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Tenerife, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Retraso en el tratamiento de la degeneración macular asociada a la edad en España" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We have read with great interest the paper by Dr. Gallego Pinazo et al.<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> titled “Functional impact of treatment with ranibizumab under reactive strategy in patients with exudative neovascular age-related macular degeneration” in which they analyze the <span class="elsevierStyleItalic">pro re nata</span> (PRN) strategy with intravitreal ranibizumab injections and maintaining or recovering visual acuity in the long-term.</p><p id="par0010" class="elsevierStylePara elsevierViewall">The authors describe the time elapsed between the first symptoms and diagnostic, and between prescription and beginning of treatment, these being 50.2<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>57.4 and 10.9<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>16 days on average, respectively. It would be interesting to know the range in both variables and whether time between diagnostic and beginning of treatment is exclusively for the hospital environment or it includes time elapsed outside of hospitals in order to obtain a better characterization of patient flow. It is known that delays in the beginning of treatment is one of the main causes of unnecessarily poor results in the treatment of neovascular ARMD with anti-VEGF medication, and the main recommendation in usual clinical practice is to shorten as much as possible the time elapsed between diagnostic and treatment.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">In the University Hospital <span class="elsevierStyleItalic">Nuestra Señora de Candelaria</span> (HUNSC), in Tenerife, Spain, we have made a retrospective analysis of patients treated for neovascular ARMD with anti-VEGF treatment between July 2014 and July 2015. The study included 67 patients and the time elapsed between diagnostic by an ophthalmologist, either out of hospital or in hospital, was one of the variables of the study. In our sample, the mean time elapse between diagnostic and treatment was 19.93<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>21.14 days, the mean being 14 days and the range between 3 and 150 days. A recent study in usual clinical practice carried out in France obtained a time lapse between diagnostic and treatment of 20.3<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>16.8 days.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a> Accordingly, it seems common practice that at present neovascular ARMD is treated after 2 weeks since diagnostic, to which we should add the time elapsed since the onset of symptoms.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Even though it seems that, in comparison to previous studies carried out in Spain,<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a> the time for beginning treatment for neovascular ARMD may have improved substantially, going from an average of 2.3 months to 10–15 days, although this improvement continues to be clearly insufficient to obtain the best visual results in daily clinic practice. Early diagnostic and optimization of hospital referral circuits and therapeutic action should be a priority for ophthalmology departments.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Abreu-González R, Alberto-Pestano M, Rubio-Rodríguez G, Abreu Reyes P. Retraso en el tratamiento de la degeneración macular asociada a la edad en España. Arch Soc Esp Oftalmol. 2017;92:e31.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:3 [ 0 => array:3 [ "identificador" => "bib0020" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:3 [ "comentario" => "[Article in English, Spanish], pii: S0365-6691(16)30158-7" "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Functional impact of treatment with ranibizumab under a reactive strategy in patients with neovascular age-related macular degeneration" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "R. Gallego-Pinazo" 1 => "R. Dolz-Marco" 2 => "M. Andreu-Fenoll" 3 => "J. Farrés" 4 => "L. 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Pazos" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Eye (Lond)" "fecha" => "2009" "volumen" => "23" "paginaInicial" => "326" "paginaFinal" => "333" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735794/0000009200000006/v1_201705310014/S2173579417300646/v1_201705310014/en/main.assets" "Apartado" => array:4 [ "identificador" => "5813" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letter to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735794/0000009200000006/v1_201705310014/S2173579417300646/v1_201705310014/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579417300646?idApp=UINPBA00004N" ]
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Letter to the Editor
Delay in age-related macular degeneration treatment in Spain
Retraso en el tratamiento de la degeneración macular asociada a la edad en España
R. Abreu-González
, M. Alberto-Pestano, G. Rubio-Rodríguez, P. Abreu Reyes
Corresponding author
Servicio de Oftalmología, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Tenerife, Spain