Share
array:24 [ "pii" => "S2173579417301135" "issn" => "21735794" "doi" => "10.1016/j.oftale.2017.02.015" "estado" => "S300" "fechaPublicacion" => "2017-08-01" "aid" => "1178" "copyright" => "Sociedad Española de Oftalmología" "copyrightAnyo" => "2017" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2017;92:394-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 18 "formatos" => array:3 [ "EPUB" => 4 "HTML" => 9 "PDF" => 5 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0365669117301181" "issn" => "03656691" "doi" => "10.1016/j.oftal.2017.02.012" "estado" => "S300" "fechaPublicacion" => "2017-08-01" "aid" => "1178" "copyright" => "Sociedad Española de Oftalmología" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2017;92:394-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 37 "formatos" => array:3 [ "EPUB" => 2 "HTML" => 29 "PDF" => 6 ] ] "es" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Comunicación corta</span>" "titulo" => "Glaucoma neonatal secundario a xantogranuloma juvenil: caso clínico" "tienePdf" => "es" "tieneTextoCompleto" => "es" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "394" "paginaFinal" => "397" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Neonatal glaucoma associated with juvenile xanthogranuloma: Case report" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 498 "Ancho" => 1500 "Tamanyo" => 154457 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">A) Exploración a los 10 meses. Típicas lesiones cutáneas de xantogranulomatosis juvenil adyacentes a aréola derecha. B) Estudio anatomopatológico de las lesiones cutáneas. La flecha señala una célula gigante de Touton. Tinción con hematoxilina-eosina.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "A. Ramos Suárez, I. Ayet Roger, A. Serra Castanera" "autores" => array:3 [ 0 => array:2 [ "nombre" => "A." "apellidos" => "Ramos Suárez" ] 1 => array:2 [ "nombre" => "I." "apellidos" => "Ayet Roger" ] 2 => array:2 [ "nombre" => "A." "apellidos" => "Serra Castanera" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2173579417301135" "doi" => "10.1016/j.oftale.2017.02.015" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579417301135?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669117301181?idApp=UINPBA00004N" "url" => "/03656691/0000009200000008/v1_201707250054/S0365669117301181/v1_201707250054/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2173579417300993" "issn" => "21735794" "doi" => "10.1016/j.oftale.2017.05.004" "estado" => "S300" "fechaPublicacion" => "2017-08-01" "aid" => "1120" "copyright" => "Sociedad Española de Oftalmología" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2017;92:398-400" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 5 "formatos" => array:3 [ "EPUB" => 1 "HTML" => 3 "PDF" => 1 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "Charles Bonnet syndrome in a child with congenital glaucoma" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "398" "paginaFinal" => "400" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Síndrome de Charles Bonnet en un niño con glaucoma congénito" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 2159 "Ancho" => 3000 "Tamanyo" => 466839 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Patient campimetry with concentric reduction in right eye and nasal step in left eye.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "E. Santos-Bueso, M. Serrador-García, F. Sáenz-Francés, C. Méndez-Hernández, L. Morales-Fernández, J.M. Martínez-de-la-Casa, J. García-Feijoo, J. Porta-Etessam" "autores" => array:8 [ 0 => array:2 [ "nombre" => "E." "apellidos" => "Santos-Bueso" ] 1 => array:2 [ "nombre" => "M." "apellidos" => "Serrador-García" ] 2 => array:2 [ "nombre" => "F." "apellidos" => "Sáenz-Francés" ] 3 => array:2 [ "nombre" => "C." "apellidos" => "Méndez-Hernández" ] 4 => array:2 [ "nombre" => "L." "apellidos" => "Morales-Fernández" ] 5 => array:2 [ "nombre" => "J.M." "apellidos" => "Martínez-de-la-Casa" ] 6 => array:2 [ "nombre" => "J." "apellidos" => "García-Feijoo" ] 7 => array:2 [ "nombre" => "J." "apellidos" => "Porta-Etessam" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0365669116302362" "doi" => "10.1016/j.oftal.2016.11.008" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669116302362?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579417300993?idApp=UINPBA00004N" "url" => "/21735794/0000009200000008/v1_201707250047/S2173579417300993/v1_201707250047/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S217357941730107X" "issn" => "21735794" "doi" => "10.1016/j.oftale.2017.05.010" "estado" => "S300" "fechaPublicacion" => "2017-08-01" "aid" => "1163" "copyright" => "Sociedad Española de Oftalmología" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2017;92:390-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 16 "formatos" => array:3 [ "EPUB" => 2 "HTML" => 11 "PDF" => 3 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "Refractory aqueous misdirection syndrome: A possible complication of penetrating keratoplasty" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "390" "paginaFinal" => "393" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Síndrome de dirección inadecuada del humor acuoso refractario: una posible complicación de la queratoplastia penetrante" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 776 "Ancho" => 2126 "Tamanyo" => 128633 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">(a) Slit lamp photographs taken on postop day one. (b) This assessment revealed athalamia with endothelial contact.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "I. Gama, W.M. Rodrigues, H.P. Filipe, M.Y. Faria, L.D. Almeida" "autores" => array:5 [ 0 => array:2 [ "nombre" => "I." "apellidos" => "Gama" ] 1 => array:2 [ "nombre" => "W.M." "apellidos" => "Rodrigues" ] 2 => array:2 [ "nombre" => "H.P." "apellidos" => "Filipe" ] 3 => array:2 [ "nombre" => "M.Y." "apellidos" => "Faria" ] 4 => array:2 [ "nombre" => "L.D." "apellidos" => "Almeida" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0365669117300576" "doi" => "10.1016/j.oftal.2017.01.012" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669117300576?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357941730107X?idApp=UINPBA00004N" "url" => "/21735794/0000009200000008/v1_201707250047/S217357941730107X/v1_201707250047/en/main.assets" ] "en" => array:20 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "Neonatal glaucoma associated with juvenile xanthogranuloma: Case report" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "394" "paginaFinal" => "397" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "A. Ramos Suárez, I. Ayet Roger, A. Serra Castanera" "autores" => array:3 [ 0 => array:4 [ "nombre" => "A." "apellidos" => "Ramos Suárez" "email" => array:1 [ 0 => "antoniomirmarbella@hotmail.com" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "I." "apellidos" => "Ayet Roger" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "A." "apellidos" => "Serra Castanera" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Oftalmología, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Oftalmología, Hospital Costa del Sol, Marbella, Málaga, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Glaucoma neonatal secundario a xantogranuloma juvenil: caso clínico" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 498 "Ancho" => 1500 "Tamanyo" => 154457 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">(A) Examination at month 10 after birth. Typical juvenile xanthogranulomatosis skin legions adjacent to the right areola. (B) Anatomopathological study of skin lesions. Arrow points to a giant Touton cell. Staining with hematoxylin-eosin.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Juvenile xanthogranuloma (JXG) is an infrequent disease that typically expresses in children with skin lesions on the torso, neck or head.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1–5</span></a> Extracutaneous involvement is also possible, with ocular compromise being most frequent.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">2,6</span></a> At the ocular level, symptomatology can range from an asymptomatic nodule in the eyelid, conjunctiva or limbus, up to severe visual compromise due to spontaneous hyphema and secondary glaucoma.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1,3,5,7</span></a></p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Clinical case</span><p id="par0015" class="elsevierStylePara elsevierViewall">Newborn male, 22 days of age, referred to the authors’ practice due to congenital glaucoma in the right eye (RE). Exploration of said eye revealed megalocornea and corneal edema that prevented the study of the anterior chamber (AC). Intraocular pressure (IOP) was 28<span class="elsevierStyleHsp" style=""></span>mmHg. treatment was initiated with oral acetazolamide and 0.5% timolol eyedrops in the RE.</p><p id="par0020" class="elsevierStylePara elsevierViewall">On postnatal day 28, considering the corneal edema improvement, goniotomy was scheduled. RE exploration under general anesthesia (EUGA) showed that corneal diameter (CD) was 14<span class="elsevierStyleHsp" style=""></span>mm and IOP 22<span class="elsevierStyleHsp" style=""></span>mmHg. Gonioscopy showed a yellowish infiltration invading the angle (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). In the view of said findings, goniotomy was canceled and topical corticoids and midriatics were added to the treatment.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">On postnatal day 35, another EUGA was performed. CD remained unchanged and IOP was 20<span class="elsevierStyleHsp" style=""></span>mmHg. The exudate now exhibited a hemorrhagic component (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B).</p><p id="par0030" class="elsevierStylePara elsevierViewall">On postnatal day 43, corneal diameter was 14.5<span class="elsevierStyleHsp" style=""></span>mm and IOP 26<span class="elsevierStyleHsp" style=""></span>mmHg. The blood component in anterior chamber had increased (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C). Serology for TORCH, toxoplasma and <span class="elsevierStyleItalic">Toxocara</span> were negative. Due to suspected diffuse of retinoblastoma, quotient of aqueous/plasmatic dehydrogenase lactate was performed, yielding normal results.</p><p id="par0035" class="elsevierStylePara elsevierViewall">Evolution with the medical treatment was positive. On postnatal month 3, CD remained unchanged and IOP was 18<span class="elsevierStyleHsp" style=""></span>mmHg with said treatment. Inferior endothelial leukoma persisted next to fibrin-hemorrhagic remains in the inferior angle (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>D).</p><p id="par0040" class="elsevierStylePara elsevierViewall">On postnatal month 3.5 an Ahmed valve was placed (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>E). One month after surgery, angle infiltration disappeared and IOP was 12<span class="elsevierStyleHsp" style=""></span>mmHg without requiring medical treatment.</p><p id="par0045" class="elsevierStylePara elsevierViewall">Ten months after birth, the patient exhibited several yellowish papulae on the torso, the anatomopathological study of which confirmed the JXG diagnostic (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>A and B).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Discussion</span><p id="par0050" class="elsevierStylePara elsevierViewall">JXG is a benign entity of unknown etiology<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a> that expresses more frequently in infants under one year of age.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">2</span></a> The typical presentation is a yellowish cutaneous papule on the torso, neck or head. These lesions generally resolve spontaneously in a period of 1–5 years.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1–5</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">The most frequent extracutaneous expression is ocular, that appears in approximately 10% of patients. In some cases it is the first expression of the disease.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1,3,5,7</span></a> It can also appear in the absence of skin lesions after these have resolved. Up to 50% of cases with ocular involvement do not exhibit simultaneous skin compromise, which increases diagnostic difficulty.</p><p id="par0060" class="elsevierStylePara elsevierViewall">The uvea is the most compromised region.<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">6</span></a> The iris could exhibit abnormal vessels with a tendency to bleed, being the main cause of spontaneous hyphema in children. In addition, it can produce secondary glaucoma due to angle infiltration.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1,6</span></a></p><p id="par0065" class="elsevierStylePara elsevierViewall">The definitive JXG diagnostic requires anatomopathological study of the lesions which show the typical giant Touton cells.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1,5</span></a> In cases with ocular involvement without skin lesions, finding histiocytes in the aqueous humor or iris biopsy could be useful.</p><p id="par0070" class="elsevierStylePara elsevierViewall">Differential diagnostic in cases with AC infiltration must be carried out with uveitis or tumor infiltration. In children, hyphema requires discarding traumatism or abuse. The most frequent cause of spontaneous hyphema in children is JXG, although blood dyscrasia, leukemia, medullary epithelioma and herpetic keratouveitis must be discarded.<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">8</span></a></p><p id="par0075" class="elsevierStylePara elsevierViewall">In contrast with skin involvements, ocular compromise does not tend toward spontaneous resolution and requires treatment.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a> There is no standard protocol and each case must be approached individually.<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">2,4</span></a> If the lesion is removable, this would be the first option. Otherwise, treatment with corticoids and topical midriatics is usually effective and does not require intensive treatment with the exception of severe complications such as glaucoma.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">2</span></a></p><p id="par0080" class="elsevierStylePara elsevierViewall">Satisfactory and definitive control of glaucoma can be achieved with medical treatment.<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">3,4,6,7,9</span></a> However, in some cases surgery is necessary.<a class="elsevierStyleCrossRef" href="#bib0085"><span class="elsevierStyleSup">8</span></a> In the present case, IOP remained under control with maximum hypotensive medication although it was decided to perform glaucoma surgery in order to avoid adverse effects of long-term oral acetazolamide treatment.</p><p id="par0085" class="elsevierStylePara elsevierViewall">By way of conclusion, collaboration with dermatologists, pediatricians and ophthalmologists is crucial for comprehensive patient management. Patients affected by cutaneous JXG should be preferentially examined by an ophthalmologist in the presence of ocular pain, red eye or altered vision.</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conflict of interests</span><p id="par0090" class="elsevierStylePara elsevierViewall">No conflict of interests was declared by the authors.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:9 [ 0 => array:3 [ "identificador" => "xres873584" "titulo" => "Abstract" "secciones" => array:2 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Case report" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Conclusion" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec862226" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres873583" "titulo" => "Resumen" "secciones" => array:2 [ 0 => array:2 [ "identificador" => "abst0015" "titulo" => "Caso clínico" ] 1 => array:2 [ "identificador" => "abst0020" "titulo" => "Conclusión" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec862225" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Clinical case" ] 6 => array:2 [ "identificador" => "sec0015" "titulo" => "Discussion" ] 7 => array:2 [ "identificador" => "sec0020" "titulo" => "Conflict of interests" ] 8 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2016-11-06" "fechaAceptado" => "2017-02-20" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec862226" "palabras" => array:5 [ 0 => "Juvenile xanthogranuloma" 1 => "Ocular" 2 => "Pediatric glaucoma" 3 => "Hyphema" 4 => "Treatment" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec862225" "palabras" => array:5 [ 0 => "Xantogranulomatosis juvenil" 1 => "Ocular" 2 => "Glaucoma pediátrico" 3 => "Hifema" 4 => "Tratamiento" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:3 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Case report</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The case concerns a 22 day-old male child with juvenile xanthogranuloma (JXG), which manifested as a unilateral glaucoma and with fibrinous hemorrhagic exudate in the anterior chamber affecting the angle of the right eye. Despite a high level of suspicion, the definitive diagnosis was not possible until the infant reached the age of 10 months, after the appearance of the skin lesions typical of this condition and histopathological study of them.</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Conclusion</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">JXG is a rare disease, characterized by yellowish skin lesions on the trunk, neck, or head. Up to 10% of cases will have ocular involvement, which is the most common extracutaneous manifestation of the disease.</p></span>" "secciones" => array:2 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Case report" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Conclusion" ] ] ] "es" => array:3 [ "titulo" => "Resumen" "resumen" => "<span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Caso clínico</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Varón de 22 días con xantogranulomatosis juvenil (XGJ) que comenzó con glaucoma unilateral y exudado fibrinohemorrágico que invadía ángulo en su ojo derecho. Pese a un alto nivel de sospecha, el diagnóstico definitivo no pudo realizarse hasta los 10 meses de vida tras la aparición y estudio anatomopatológico de las típicas lesiones cutáneas.</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Conclusión</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La XGJ es una enfermedad poco frecuente caracterizada por lesiones cutáneas amarillentas en tronco, cuello o cabeza. Hasta el 10% de casos pueden presentar afectación ocular siendo la manifestación extracutánea más frecuente de la enfermedad.</p></span>" "secciones" => array:2 [ 0 => array:2 [ "identificador" => "abst0015" "titulo" => "Caso clínico" ] 1 => array:2 [ "identificador" => "abst0020" "titulo" => "Conclusión" ] ] ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Ramos Suárez A, Ayet Roger I, Serra Castanera A. Glaucoma neonatal secundario a xantogranuloma juvenil: caso clínico. Arch Soc Esp Oftalmol. 2017;92:394–397.</p>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1821 "Ancho" => 1400 "Tamanyo" => 277073 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">(A) Gonioscopy on postnatal day 28, showing the existence of yellowish infiltrate in the angle. (B) Examination On postnatal day 35, showing fibrin-hemorrhagic component in the inferior angle. (C) Examination on postnatal day 43, showing hyphema with remains of yellowish fibrinous material. Presence of yellowish material over anterior lens capsule. Small central corneal leukoma. (D) Examination at postnatal month 3, showing nearly complete corneal edema resolution, with persistence of central corneal leukoma and an additional inferior endothelial leukoma. Persistence of minimum fibrinous-hemorrhagic remains in the inferior angle. (E) Insertion of Ahmed valve. Absence of corneal edema with persistence of central and inferior leukoma. No angle infiltration. The arrow points to the Ahmed valve tube in anterior chamber.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 498 "Ancho" => 1500 "Tamanyo" => 154457 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">(A) Examination at month 10 after birth. Typical juvenile xanthogranulomatosis skin legions adjacent to the right areola. (B) Anatomopathological study of skin lesions. Arrow points to a giant Touton cell. Staining with hematoxylin-eosin.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:9 [ 0 => array:3 [ "identificador" => "bib0050" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The epidemiology, clinical characteristics, histopathology and management of juvenile and adult onset corneoscleral limbus xanthogranuloma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "G. Kontos" 1 => "S. Borooah" 2 => "A. Khan" 3 => "B.W. Fleck" 4 => "S.E. Coupland" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Graefes Arch Clin and Exp Ophthalmol" "fecha" => "2016" "volumen" => "254" "paginaInicial" => "413" "paginaFinal" => "420" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0055" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ocular juvenile xanthogranuloma" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L. Niu" 1 => "C. Zhang" 2 => "F. Meng" 3 => "R. Cai" 4 => "Y. Bi" 5 => "Y. Wang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/OPX.0000000000000609" "Revista" => array:6 [ "tituloSerie" => "Optom Vis Sci" "fecha" => "2015" "volumen" => "92" "paginaInicial" => "e126" "paginaFinal" => "e133" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25969381" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0060" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "New ultrasound biomicroscopy iris findings in juvenile xanthogranuloma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "Z. Syed" 1 => "T. Chen" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/IJG.0000000000000443" "Revista" => array:6 [ "tituloSerie" => "J Glaucoma" "fecha" => "2016" "volumen" => "25" "paginaInicial" => "e759" "paginaFinal" => "e760" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27483333" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0065" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Juvenile xanthogranulomatosis with bilateral and multifocal ocular lesions of the iris, cornealscleral limbus, and choroid" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "S. Longmuir" 1 => "A. Dumitrescu" 2 => "Y. Kwon" 3 => "H.C. Boldt" 4 => "S. Hong" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jaapos.2011.07.011" "Revista" => array:6 [ "tituloSerie" => "J AAPOS" "fecha" => "2011" "volumen" => "15" "paginaInicial" => "598" "paginaFinal" => "600" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22153409" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0070" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Juvenile xanthogranuloma of the corneoscleral limbus: case report and review of the literature" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "A. ChaudhryI" 1 => "Z. Al-Jishi" 2 => "F.A. Shamsi" 3 => "F. Riley" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.survophthal.2004.08.004" "Revista" => array:6 [ "tituloSerie" => "Surv Ophthalmol" "fecha" => "2004" "volumen" => "49" "paginaInicial" => "608" "paginaFinal" => "614" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15530947" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0075" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Juvenile xanthogranuloma (concurrent involvement of skin and eye)" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A.S. Rad" 1 => "A. Kheradvar" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Cornea" "fecha" => "2001" "volumen" => "20" "paginaInicial" => "760" "paginaFinal" => "762" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11588432" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0080" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Juvenile xanthogranuloma with ocular involvement" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. Liang" 1 => "Y.H. Liu" 2 => "K. Fang" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1111/j.1525-1470.2009.00893.x" "Revista" => array:6 [ "tituloSerie" => "Pediatr Dermatol" "fecha" => "2009" "volumen" => "26" "paginaInicial" => "232" "paginaFinal" => "234" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19419487" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0085" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "The child with spontaneous recurrent bleeding in the eye" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Rao" 1 => "D. Padhy" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1136/bcr-2014-203925" "Revista" => array:2 [ "tituloSerie" => "BMJ Case Rep" "fecha" => "2014" ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0090" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Three different ophthalmic presentations of juvenile xanthogranuloma" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "H.H.W. Lau" 1 => "W.W.K. Yip" 2 => "A. Lee" 3 => "C. Lai" 4 => "D.S.P. Fan" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Hong Kong Med J" "fecha" => "2014" "volumen" => "20" "paginaInicial" => "261" "paginaFinal" => "263" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24914080" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735794/0000009200000008/v1_201707250047/S2173579417301135/v1_201707250047/en/main.assets" "Apartado" => array:4 [ "identificador" => "5812" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Short communications" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735794/0000009200000008/v1_201707250047/S2173579417301135/v1_201707250047/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579417301135?idApp=UINPBA00004N" ]
