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Abreu-González, J.I. Fernández-Vigo, J. Donate-López" "autores" => array:3 [ 0 => array:4 [ "nombre" => "R." "apellidos" => "Abreu-González" "email" => array:1 [ 0 => "rodrigoabreug@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "J.I." "apellidos" => "Fernández-Vigo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "J." "apellidos" => "Donate-López" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Oftalmología, Hospital Universitario La Candelaria, Tenerife, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Oftalmología, Hospital Universitario Clínico San Carlos, Madrid, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Evaluación mediante imagen de campo amplio y ultracampo amplio en la retinopatía diabética: definición y razones para ser presente en vez de futuro" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 902 "Ancho" => 1255 "Tamanyo" => 321583 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Composition of widefield images in patients with proliferative diabetic retinopathy. A: 163° UWF colour fundus photograph (Mirante®, Nidek®, Gamagori, Japan); B: 12 × mm12 OCT-A (Cirrus®, Carl Zeiss Meditec®, Jena, Germany); C: 23 mm UWF OCT (Silverstone®, Optos®, Dunfermline, UK).</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Lately, Wide Field (WF) and Ultra Wide Field (UWF) imaging is strongly emerging as an option in multimodal retinal diagnostic imaging, both in retinography and in optical coherence tomography (OCT) and angiography using OCT (OCT-A),<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> although it is true that wide field contrast angiography has been the first modality to be incorporated into our daily practice.<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> This is considered especially useful for retinal pathologies with an important component of peripheral retinal involvement and high prevalence, such as diabetic retinopathy.<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Conventional 30−50° colour retinography appeared last century, while structural OCT celebrates its 30th anniversary this year and OCT-A is still far from a decade old. The WF version of the 3 diagnostic imaging modalities in retina and UWF for retinography and OCT are now commercially available, which is leading to an increasing number of publications and communications, and is currently one of the topics that attracts most interest at congresses due to its relevance in clinical practice.</p><p id="par0015" class="elsevierStylePara elsevierViewall">The current gold standard for the classification of diabetic retinopathy is the Early Treatment Diabetic Retinopathy Study (ETDRS)<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> scale, which is based on 7-field retinography and has the following limitations: it has limited accuracy, it may be insufficient for the assessment of the peripheral effect of new intravitreal treatments against vascular endothelial growth factor and most clinicians do not use it due to its complexity. Accordingly, tthe most widely used classification is the International Diabetic Retinopathy Severity Scale.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">Before considering their implementation in our daily clinical practice, the first we need to know is the clear and precise definition of WF and UWF for the 3 imaging modalities and then evaluate the advantages and disadvantages of their use in the management of patients with diabetic retinopathy:</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Definition</span><p id="par0025" class="elsevierStylePara elsevierViewall">For both retinography and OCT, UWF is considered if the image reaches the area anterior to the exit of the vortical veins of the retina and WF if the image only reaches the area of the retina between the posterior pole (24 × 24 mm centred on the fovea) and anterior to the vortices.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> However for OCT-A, due to current technological development, WF is defined if the image is greater than 70° centred in fovea and UWF if greater than 90° centred in fovea (an assembly of 2 images of 15 × 9 mm). For the definition of the location of the structural OCT B-scan slice we used the following concepts: mid periphery (60−100°) and far periphery (110−220°)<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Advantages of WF and UWF assessment</span><p id="par0030" class="elsevierStylePara elsevierViewall">With the WF and UWF image we can assess the central and peripheral retina of the diabetic patient and, above all, define whether our patient has predominantly central or peripheral diabetic retinopathy (hemorrhages and microaneurysms, intraretinal vascular anomalies or neovessels located 60% outside the ETDRS fields), as in 10% of cases peripheral lesions indicate a more severe degree of diabetic retinopathy than when assessed with the ETDRS classification alone.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> By having all the information in a single image, the fundus of a diabetic patient could be seen better and faster, and funduscopy could probably become dispensable.</p><p id="par0035" class="elsevierStylePara elsevierViewall">With the new OCT systems, both WF and UWF OCT-A allow us to better define and quantify vascular lesions and areas of ischemia when compared to conventional fluorescein angiography<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">9</span></a> and even characterise the pattern and density of individual retinal vascular plexuses.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> OCT, with WF and UWF images, also provides important information for planning treatment with focal laser photocoagulation or assessing the overall effect on diffuse edema after intravitreal treatment.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Disadvantages</span><p id="par0040" class="elsevierStylePara elsevierViewall">The main disadvantage is the monetary cost since, in most cases, we would be forced to incorporate new imaging equipment, with higher prices than current retinography or OCT systems and much higher than the price of a standard 45° colour retinograph and the consequent readjustment of workflows, since we would require ancillary equipment to carry out these tests, which require time for their acquisition.</p><p id="par0045" class="elsevierStylePara elsevierViewall">There is a small learning curve in capturing and interpreting WF and UWF images, as they are not new image modalities, but the same as those we use now with a much larger capture area.</p><p id="par0050" class="elsevierStylePara elsevierViewall">Based on the above, and the technological evolution and improvement that WF and UWF equipment has undergone in recent times, both for retinography, OCT and OCT-A, there is no doubt that these types of retinal imaging systems are already a great advance that is allowing us to be more efficient and make less invasive and more accurate diagnoses for our patients with diabetes, whether or not they have already developed diabetic retinopathy, which will lead to health outcomes that will not take long to be observed and have a great impact on the health of our society. Therefore, in our opinion, the advantages offered by WF and UWF imaging in diabetic retinopathy justify its progressive implementation in daily clinical practice.</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Funding</span><p id="par0055" class="elsevierStylePara elsevierViewall">This work has not received any funding.</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conflict of interest</span><p id="par0060" class="elsevierStylePara elsevierViewall">No conflicts of interest were declared by the authors.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:6 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Definition" ] 1 => array:2 [ "identificador" => "sec0010" "titulo" => "Advantages of WF and UWF assessment" ] 2 => array:2 [ "identificador" => "sec0015" "titulo" => "Disadvantages" ] 3 => array:2 [ "identificador" => "sec0020" "titulo" => "Funding" ] 4 => array:2 [ "identificador" => "sec0025" "titulo" => "Conflict of interest" ] 5 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Abreu-González R, Fernández-Vigo JI, Donate-López J. Evaluación mediante imagen de campo amplio y ultracampo amplio en la retinopatía diabética: definición y razones para ser presente en vez de futuro. Arch Soc Esp Oftalmol. 2022;97:181–183.</p>" ] ] "multimedia" => array:1 [ 0 => array:8 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 902 "Ancho" => 1255 "Tamanyo" => 321583 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at0005" "detalle" => "Fig. " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Composition of widefield images in patients with proliferative diabetic retinopathy. A: 163° UWF colour fundus photograph (Mirante®, Nidek®, Gamagori, Japan); B: 12 × mm12 OCT-A (Cirrus®, Carl Zeiss Meditec®, Jena, Germany); C: 23 mm UWF OCT (Silverstone®, Optos®, Dunfermline, UK).</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:10 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Ultra-wide-field imaging in diabetic retinopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "K. Ghasemi Falavarjani" 1 => "I. Tsui" 2 => "S.R. 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Editorial
Wide field and ultra wide field image evaluation in diabetic retinopathy: Definition and reasons for to be present instead of future
Evaluación mediante imagen de campo amplio y ultracampo amplio en la retinopatía diabética: definición y razones para ser presente en vez de futuro