Short communication
Bilateral polypoidal choroidal vasculopathy coexisting with exudative and atrophic age-related macular degeneration
Vasculopatía coroidea polipoidea bilateral, coexistiendo con degeneración macular asociada a la edad exudativa y atrófica
J.R. Aronés-Santivañez
, A. Dyrda, I. Alarcón Valero
Corresponding author
Departamento de Oftalmología, Parc de Salut Mar, Hospital de la Esperanza, Barcelona, Spain
Read
123
Timeswas read the article
12
Total PDF
111
Total HTML
Share statistics
array:23 [ "pii" => "S2173579416301013" "issn" => "21735794" "doi" => "10.1016/j.oftale.2016.07.007" "estado" => "S300" "fechaPublicacion" => "2016-12-01" "aid" => "999" "copyrightAnyo" => "2016" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2016;91:604-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 125 "formatos" => array:3 [ "EPUB" => 3 "HTML" => 110 "PDF" => 12 ] ] "Traduccion" => array:1 [ "es" => array:18 [ "pii" => "S0365669116001192" "issn" => "03656691" "doi" => "10.1016/j.oftal.2016.02.014" "estado" => "S300" "fechaPublicacion" => "2016-12-01" "aid" => "999" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2016;91:604-7" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 332 "formatos" => array:3 [ "EPUB" => 19 "HTML" => 280 "PDF" => 33 ] ] "es" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Comunicación corta</span>" "titulo" => "Vasculopatía coroidea polipoidea bilateral, coexistiendo con degeneración macular asociada a la edad exudativa y atrófica" "tienePdf" => "es" "tieneTextoCompleto" => "es" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "604" "paginaFinal" => "607" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Bilateral polypoidal choroidal vasculopathy coexisting with exudative and atrophic age-related macular degeneration" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figura 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 492 "Ancho" => 1800 "Tamanyo" => 114532 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Retinografías en ambos ojos al seguimiento del año.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J.R. Aronés-Santivañez, A. Dyrda, I. Alarcón Valero" "autores" => array:3 [ 0 => array:2 [ "nombre" => "J.R." "apellidos" => "Aronés-Santivañez" ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Dyrda" ] 2 => array:2 [ "nombre" => "I." "apellidos" => "Alarcón Valero" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2173579416301013" "doi" => "10.1016/j.oftale.2016.07.007" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579416301013?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669116001192?idApp=UINPBA00004N" "url" => "/03656691/0000009100000012/v1_201612011634/S0365669116001192/v1_201612011634/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2173579416301372" "issn" => "21735794" "doi" => "10.1016/j.oftale.2016.09.014" "estado" => "S300" "fechaPublicacion" => "2016-12-01" "aid" => "1029" "copyright" => "Sociedad Española de Oftalmología" "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Arch Soc Esp Oftalmol. 2016;91:608" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 148 "formatos" => array:3 [ "EPUB" => 5 "HTML" => 129 "PDF" => 14 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "The unexplainable drift of the MIR examination questions on macular disease" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "608" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "La inexplicable deriva de las preguntas del examen MIR hacia la patología macular" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. González Martín-Moro" "autores" => array:1 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "González Martín-Moro" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0365669116300211" "doi" => "10.1016/j.oftal.2016.03.020" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669116300211?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579416301372?idApp=UINPBA00004N" "url" => "/21735794/0000009100000012/v1_201612011629/S2173579416301372/v1_201612011629/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S2173579416300536" "issn" => "21735794" "doi" => "10.1016/j.oftale.2016.05.005" "estado" => "S300" "fechaPublicacion" => "2016-12-01" "aid" => "992" "copyright" => "Sociedad Española de Oftalmología" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2016;91:599-603" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 132 "formatos" => array:3 [ "EPUB" => 25 "HTML" => 82 "PDF" => 25 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "Spironolactone, a therapeutic alternative in the treatment of diffuse retinal pigment epitheliopathy" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "599" "paginaFinal" => "603" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Espironolactona, alternativa terapéutica en el tratamiento de la epiteliopatía difusa crónica" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1835 "Ancho" => 1500 "Tamanyo" => 379763 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Retinography, FAG and autofluorescence of the first patient at diagnostic, evidencing bilateral diffuse chronic epitheliopathy, showing hyperfluorescence diffuse RPE alteration areas in both eyes.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "D. Ángel-Pereira, P. Rocha-Cabrera, L. Cordovés-Dorta, M.J. Losada Castillo, A. Blasco Alberto, J.A. Abreu Reyes" "autores" => array:6 [ 0 => array:2 [ "nombre" => "D." "apellidos" => "Ángel-Pereira" ] 1 => array:2 [ "nombre" => "P." "apellidos" => "Rocha-Cabrera" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Cordovés-Dorta" ] 3 => array:2 [ "nombre" => "M.J." "apellidos" => "Losada Castillo" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "Blasco Alberto" ] 5 => array:2 [ "nombre" => "J.A." "apellidos" => "Abreu Reyes" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S036566911600112X" "doi" => "10.1016/j.oftal.2016.02.007" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S036566911600112X?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579416300536?idApp=UINPBA00004N" "url" => "/21735794/0000009100000012/v1_201612011629/S2173579416300536/v1_201612011629/en/main.assets" ] "en" => array:20 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "Bilateral polypoidal choroidal vasculopathy coexisting with exudative and atrophic age-related macular degeneration" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "604" "paginaFinal" => "607" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "J.R. Aronés-Santivañez, A. Dyrda, I. Alarcón Valero" "autores" => array:3 [ 0 => array:4 [ "nombre" => "J.R." "apellidos" => "Aronés-Santivañez" "email" => array:1 [ 0 => "arjansa@gmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "A." "apellidos" => "Dyrda" ] 2 => array:2 [ "nombre" => "I." "apellidos" => "Alarcón Valero" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Departamento de Oftalmología, Parc de Salut Mar, Hospital de la Esperanza, Barcelona, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Vasculopatía coroidea polipoidea bilateral, coexistiendo con degeneración macular asociada a la edad exudativa y atrófica" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 492 "Ancho" => 1801 "Tamanyo" => 121312 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Retinographs in both eyes at one year follow-up.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Even though age-related macular degeneration (AMD) is the most common maculopathy in the Western world and treatment protocols are well known, there are other difficult to treat forms of choroidal neovascularization which are not yet broadly known. For this reason, the authors decided to report the clinic case of a patient that concurrently exhibited polyps due to polypoidal choroidal vasculopathy (PCV) in both eyes and exudative AMD in one eye and atrophic AMD in the other.</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Clinic case report</span><p id="par0010" class="elsevierStylePara elsevierViewall">Female nurse, who visited due to diminished visual acuity (VA) and metamorphopsia in the left eye (LE) with 2 months evolution. Pathological antecedents comprised adequately managed arterial hypertension and dyslipidemia. Ophthalmological antecedents included pseudophakia in both eyes and AMD, referring poor vision in the right eye (RE). Examination produced VA of 20/400 in the RE and 20/133 in the LE, intraocular pressure of 14<span class="elsevierStyleHsp" style=""></span>mmHg in both eyes and bilateral pseudophakia. RE posterior segment showed a cicatricial lesion in the macula and abundant drusen in posterior pole, while the LE showed a juxtapapillary orange elevated lesion surrounded by lipid deposits, and another inferior subfoveal greenish-grayish lesion with perilesional hemorrhage.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Fluorescein angiography (FA) of the LE defined a subfoveal hyperfluorescence corresponding to a classic neovascular membrane and juxtapapillary lesion, with a hypo-fluorescent component probably due to the presence of lipid ring-shaped deposits in addition to a rounded lesion in the center of the exudative ring, which could correspond to polyps. Accordingly, it was decided to carry out indocyanine green angiography (IGA), which showed in the right eye a juxtapapillary hyper-fluorescent disciform scar that was difficult to define.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Since early IGA times, the presence of juxtapapillary hotspots were evidenced in both eyes, corresponding to juxtapapillary polyps. Retinographs, FA and IGA for both eyes are shown in <a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">On the basis of said results, it was decided to carry out photodynamic therapy (PDT) at standard dose as well as anti-vascular endothelial growth factor (VEGF) injections (ranibizumab: 0.5<span class="elsevierStyleHsp" style=""></span>mg/0.05<span class="elsevierStyleHsp" style=""></span>ml) on 3 occasions, achieving lesion stability. Optical coherence tomography (OCT) is shown in <a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>, with evolution in LE. Follow-up during one year comprised resolution of lipid deposits and diminished size of lesions, shown in <a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>. However, VA did not improve significantly. At the last visit after 2 years, the patient remained stable (<a class="elsevierStyleCrossRef" href="#fig0020">Fig. 4</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><elsevierMultimedia ident="fig0020"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Discussion</span><p id="par0030" class="elsevierStylePara elsevierViewall">Idiopathic PCV is characterized by alterations in vascular network ramifications starting from the internal choroids, producing terminations similar to aneurysms (polyps) which can dilate and bleed.<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> Initially, PCV was described in Afro-American females between the fourth and seventh decade of life, but at present cases have been reported in different races, age groups and genders, and were frequently confused with neovascular forms of AMD. Clinically, PCV expresses as generally juxtapapillary reddish-orange nodules that produce hemorrhagic retina pigment epithelium (RPE) detachments which tend to be multiple and recurring.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> IGA is important for studying and following up PCV as it shows choroidal circulation in greater detail.</p><p id="par0035" class="elsevierStylePara elsevierViewall">The clinic case reported herein is quite unique as the patient exhibited PCV with atrophic AMD in one eye and exudative AMD in the other, with independent lesions. Only 2 publications have been found that report the coexistence of PCV and exudative AMD, of which one<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> did not include IGA and the other<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> was a unilateral presentation and did not describe treatment. Other studies<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> reported the development of polypoid lesions such as neovascularization progression in the subretinal pigment epithelium, but not independently as seen in the present case. It was decided to apply combined therapy with anti-VEGF and PDT as, according to the EVEREST study,<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a> combined treatment is superior to exclusively anti-VEGF treatment. In the present case, lesion stabilization was achieved while VA remained stable.</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0070">Conclusion</span><p id="par0040" class="elsevierStylePara elsevierViewall">The coexistence of choroidal polypoid vasculopathy and exudative AMD is possible. The presence of polyps is usually juxtapapillary, in contrast with neovascular membranes which are generally foveal. When suspecting CPV, IGA should be performed. Combined therapy comprising PDT and anti-VEGF could be an alternative in this type of patient.</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Conflict of interests</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors of the present article have no commercial or financial interests in relation to any product or technique described herein.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:10 [ 0 => array:3 [ "identificador" => "xres764856" "titulo" => "Abstract" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Objective" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Case report" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Conclusion" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec766285" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres764855" "titulo" => "Resumen" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "abst0020" "titulo" => "Objetivo" ] 1 => array:2 [ "identificador" => "abst0025" "titulo" => "Caso clínico" ] 2 => array:2 [ "identificador" => "abst0030" "titulo" => "Conclusión" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec766286" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Clinic case report" ] 6 => array:2 [ "identificador" => "sec0015" "titulo" => "Discussion" ] 7 => array:2 [ "identificador" => "sec0020" "titulo" => "Conclusion" ] 8 => array:2 [ "identificador" => "sec0025" "titulo" => "Conflict of interests" ] 9 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2015-01-20" "fechaAceptado" => "2016-02-18" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec766285" "palabras" => array:5 [ 0 => "Age-related macular degeneration" 1 => "Polypoidal choroidal vasculopathy" 2 => "Indocyanine angiography" 3 => "Photodynamic therapy" 4 => "Anti-VEGF" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec766286" "palabras" => array:5 [ 0 => "Degeneración macular asociada a la edad" 1 => "Vasculopatía coroidea polipoidea" 2 => "Angiografía con verde indocianina" 3 => "Terapia fotodinámica" 4 => "Anti-VEGF" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:3 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To present the case of simultaneous presentation of polypoidal choroidal vasculopathy (PCV) and aged-related macular degeneration (AMD).</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Case report</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">An 83-year-old woman presented with decreased vision in the left eye (LE). In the examination there was an orange peripapillary lesion surrounded by lipid exudates and another subfoveal grayish lesion in the LE. Disciform scarring was observed in the right eye. Fluorescein angiography showed a classic neovascular membrane in in the LE fovea. Indocyanine angiography (ICGA) showed a polyp-like peri-papillary aneurysmal dilation in both eyes. The patient was treated with photodynamic therapy and anti-VEFG injections with stabilization of the lesions.</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Conclusion</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">PCV and AMD can co-exist in unusual cases. When PCV is suspected, ICGA is mandatory for diagnosis.</p></span>" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Objective" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Case report" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Conclusion" ] ] ] "es" => array:3 [ "titulo" => "Resumen" "resumen" => "<span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Objetivo</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Presentar el caso clínico de un paciente que presenta vasculopatía coroidea polipoidea (VCP) bilateral y degeneración macular asociada a la edad (DMAE) exudativa y atrófica, su tratamiento.</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Caso clínico</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Mujer de 83 años presenta disminución de agudeza visual en el ojo izquierdo (OI). Al examen presenta DMAE atrófica en el OD, y en el OI una lesión naranja yuxtapapilar con depósitos lipídicos y otra gris subfoveal inferior. En la angiografía fluoresceínica y de verde de indocianina (AVI) se evidencia una membrana neovascular clásica en el OI, y pólipos yuxtapapilares en ambos ojos. Se realiza terapia fotodinámica con inyecciones anti-VEGF con estabilización de lesiones.</p></span> <span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conclusión</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La coexistencia de la vasculopatía polipoidea coroidea y la DMAE exudativa es posible. Ante la sospecha de VCP debe realizarse AVI.</p></span>" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "abst0020" "titulo" => "Objetivo" ] 1 => array:2 [ "identificador" => "abst0025" "titulo" => "Caso clínico" ] 2 => array:2 [ "identificador" => "abst0030" "titulo" => "Conclusión" ] ] ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Aronés-Santivañez JR, Dyrda A, Alarcón Valero I. Vasculopatía coroidea polipoidea bilateral, coexistiendo con degeneración macular asociada a la edad exudativa y atrófica. Arch Soc Esp Oftalmol. 2016;91:597–600.</p>" ] ] "multimedia" => array:4 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 972 "Ancho" => 1901 "Tamanyo" => 205694 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">(A) LE retinograph showing peripapillary lesions surrounded by lipid exudates (small arrow) and another grayish subfoveal lesion with perilesional hemorrhage (long arrow). (B) Classic neovascular membrane in RE fovea. (C) IGA showing hotspot in polypoid peripapillary lesion. (D) RE retinograph showing disciform scar. (E) FA in RE. (F) IGA showing hotspot with arrow.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1032 "Ancho" => 1501 "Tamanyo" => 405945 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Left eye OCT, before and after treatment.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 492 "Ancho" => 1801 "Tamanyo" => 121312 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Retinographs in both eyes at one year follow-up.</p>" ] ] 3 => array:7 [ "identificador" => "fig0020" "etiqueta" => "Fig. 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 1364 "Ancho" => 1400 "Tamanyo" => 200807 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Retinographs and autofluorescence of both eyes with 2 years evolution.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:6 [ 0 => array:3 [ "identificador" => "bib0035" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Polypoidal choroidal vasculopathy pattern in age-related macular degeneration: a clinicopathologic correlation" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "B.A. Lafaut" 1 => "S. Aisenbery" 2 => "C. van den Broecke" 3 => "K.U. Bartz-Schmidt" 4 => "K. Heimann" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Retina" "fecha" => "2000" "volumen" => "20" "paginaInicial" => "650" "paginaFinal" => "654" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11131419" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0040" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Polypoidal choroidal vasculopathy and neovascularized age-related macular degeneration" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "L.A. Yannuzzi" 1 => "D.W. Wong" 2 => "B.S. Sforzolini" 3 => "M. Goldbaum" 4 => "K.C. Tang" 5 => "R.F. Spaide" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Arch Ophthalmol" "fecha" => "1999" "volumen" => "117" "paginaInicial" => "1503" "paginaFinal" => "1510" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10565519" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0045" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Idiopathic polypoidal choroidal vasculopathy presenting with simultaneous choroidal neovascular membrane" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "D. Shechtman" 1 => "J.A. Tyler" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Optom Vis Sci" "fecha" => "2004" "volumen" => "81" "paginaInicial" => "491" "paginaFinal" => "549" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15252347" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0050" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Polypoidal choroidal vasculopathy coexisting with exudative age-related macular degeneration" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "Y. Chen" 1 => "F. Wen" 2 => "Z. Sun" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s10792-007-9113-2" "Revista" => array:6 [ "tituloSerie" => "Int Ophthalmol" "fecha" => "2008" "volumen" => "28" "paginaInicial" => "119" "paginaFinal" => "123" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17603771" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0055" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Development of polypoidal lesions in age-related macular degeneration" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Tsujikawa" 1 => "Y. Ojima" 2 => "K. Yamashiro" 3 => "S. Ooto" 4 => "H. Tamura" 5 => "I. Nakata" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1038/eye.2010.232" "Revista" => array:6 [ "tituloSerie" => "Eye" "fecha" => "2011" "volumen" => "25" "paginaInicial" => "481" "paginaFinal" => "488" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21252945" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0060" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "EVEREST study: efficacy and safety of verteporfin photodynamic therapy in combination with ranibizumab or alone versus ranibizumab monotherapy in patients with symptomatic macular polypoidal choroidal vasculopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A. Koh" 1 => "W.K. Lee" 2 => "L.J. Chen" 3 => "S.J. Chen" 4 => "Y. Hashad" 5 => "H. Kim" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1097/IAE.0b013e31824f91e8" "Revista" => array:6 [ "tituloSerie" => "Retina" "fecha" => "2012" "volumen" => "32" "paginaInicial" => "1453" "paginaFinal" => "1464" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22426346" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735794/0000009100000012/v1_201612011629/S2173579416301013/v1_201612011629/en/main.assets" "Apartado" => array:4 [ "identificador" => "5812" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Short communications" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735794/0000009100000012/v1_201612011629/S2173579416301013/v1_201612011629/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579416301013?idApp=UINPBA00004N" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2023 March | 1 | 0 | 1 |
| 2018 February | 3 | 2 | 5 |
| 2018 January | 8 | 0 | 8 |
| 2017 December | 9 | 3 | 12 |
| 2017 November | 15 | 1 | 16 |
| 2017 October | 17 | 0 | 17 |
| 2017 September | 16 | 0 | 16 |
| 2017 August | 14 | 2 | 16 |
| 2017 July | 11 | 2 | 13 |
| 2017 June | 16 | 1 | 17 |
| 2017 May | 0 | 1 | 1 |
| 2016 December | 1 | 0 | 1 |
