Short communication
Bilateral exudative retinal detachment associated with central serous chorioretinopathy in a patient treated with corticosteroids
Desprendimiento de retina exudativo bilateral asociado con coriorretinopatía serosa central en una paciente tratada con corticoesteroides
T. Rueda-Rueda, J.L. Sánchez-Vicente, L. Llerena-Manzorro
, A. Medina-Tapia, L. González-García, A. Alfaro-Juárez, C. Vital-Berral, F. López-Herrero, A. Muñoz-Morales, L.S. Ortega, Á. Herrador-Montiel
Corresponding author
Hospital Universitario Virgen del Rocío, Sevilla, Spain
Read
2
Timeswas read the article
1
Total PDF
1
Total HTML
Share statistics
array:24 [ "pii" => "S2173579417301068" "issn" => "21735794" "doi" => "10.1016/j.oftale.2017.05.009" "estado" => "S300" "fechaPublicacion" => "2017-10-01" "aid" => "1148" "copyright" => "Sociedad Española de Oftalmología" "copyrightAnyo" => "2017" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2017;92:481-5" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0365669117300230" "issn" => "03656691" "doi" => "10.1016/j.oftal.2017.01.002" "estado" => "S300" "fechaPublicacion" => "2017-10-01" "aid" => "1148" "copyright" => "Sociedad Española de Oftalmología" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2017;92:481-5" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 58 "formatos" => array:2 [ "HTML" => 47 "PDF" => 11 ] ] "es" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Comunicación corta</span>" "titulo" => "Desprendimiento de retina exudativo bilateral asociado con coriorretinopatía serosa central en una paciente tratada con corticoesteroides" "tienePdf" => "es" "tieneTextoCompleto" => "es" "tieneResumen" => array:2 [ 0 => "es" 1 => "en" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "481" "paginaFinal" => "485" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Bilateral exudative retinal detachment associated with central serous chorioretinopathy in a patient treated with corticosteroids" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0025" "etiqueta" => "Figura 5" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr5.jpeg" "Alto" => 1208 "Ancho" => 2500 "Tamanyo" => 249452 ] ] "descripcion" => array:1 [ "es" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Estado final de los 2<span class="elsevierStyleHsp" style=""></span>ojos. Intensa fibrosis subretiniana, atrofia e hipertrofia del EPR y membranas epiretinianas.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "T. Rueda-Rueda, J.L. Sánchez-Vicente, L. Llerena-Manzorro, A. Medina-Tapia, L. González-García, A. Alfaro-Juárez, C. Vital-Berral, F. López-Herrero, A. Muñoz-Morales, L.S. Ortega, Á. Herrador-Montiel" "autores" => array:11 [ 0 => array:2 [ "nombre" => "T." "apellidos" => "Rueda-Rueda" ] 1 => array:2 [ "nombre" => "J.L." "apellidos" => "Sánchez-Vicente" ] 2 => array:2 [ "nombre" => "L." "apellidos" => "Llerena-Manzorro" ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Medina-Tapia" ] 4 => array:2 [ "nombre" => "L." "apellidos" => "González-García" ] 5 => array:2 [ "nombre" => "A." "apellidos" => "Alfaro-Juárez" ] 6 => array:2 [ "nombre" => "C." "apellidos" => "Vital-Berral" ] 7 => array:2 [ "nombre" => "F." "apellidos" => "López-Herrero" ] 8 => array:2 [ "nombre" => "A." "apellidos" => "Muñoz-Morales" ] 9 => array:2 [ "nombre" => "L.S." "apellidos" => "Ortega" ] 10 => array:2 [ "nombre" => "Á." "apellidos" => "Herrador-Montiel" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2173579417301068" "doi" => "10.1016/j.oftale.2017.05.009" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579417301068?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669117300230?idApp=UINPBA00004N" "url" => "/03656691/0000009200000010/v1_201709270108/S0365669117300230/v1_201709270108/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2173579417301056" "issn" => "21735794" "doi" => "10.1016/j.oftale.2017.05.008" "estado" => "S300" "fechaPublicacion" => "2017-10-01" "aid" => "1138" "copyright" => "Sociedad Española de Oftalmología" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2017;92:486-9" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "Radiation retinopathy secondary to treatment of maxillary sinus carcinoma: A dramatic case" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "486" "paginaFinal" => "489" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Retinopatía por radiación secundaria a tratamiento de carcinoma de seno maxilar: un caso dramático" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 916 "Ancho" => 1600 "Tamanyo" => 142560 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Facial CAT with intravenous contrast. Right maxillary tumor (arrows) involving the destruction of all maxillary sinus walls with medial extension toward the nasal fossa (A) and cranial toward the orbit (B).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "J. Galindo-Bocero, S. Macías-Franco, S. Sánchez-García, M. Fonollá-Gil, A. García-Alonso" "autores" => array:5 [ 0 => array:2 [ "nombre" => "J." "apellidos" => "Galindo-Bocero" ] 1 => array:2 [ "nombre" => "S." "apellidos" => "Macías-Franco" ] 2 => array:2 [ "nombre" => "S." "apellidos" => "Sánchez-García" ] 3 => array:2 [ "nombre" => "M." "apellidos" => "Fonollá-Gil" ] 4 => array:2 [ "nombre" => "A." "apellidos" => "García-Alonso" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0365669117300138" "doi" => "10.1016/j.oftal.2016.11.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669117300138?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579417301056?idApp=UINPBA00004N" "url" => "/21735794/0000009200000010/v1_201709270057/S2173579417301056/v1_201709270057/en/main.assets" ] "itemAnterior" => array:19 [ "pii" => "S217357941730141X" "issn" => "21735794" "doi" => "10.1016/j.oftale.2017.07.003" "estado" => "S300" "fechaPublicacion" => "2017-10-01" "aid" => "1152" "copyright" => "Sociedad Española de Oftalmología" "documento" => "article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Arch Soc Esp Oftalmol. 2017;92:477-80" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "BIlateral juxtapapillary retinal capillary haemangioma: Usefulness of aflibercept in the management of its complications" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "477" "paginaFinal" => "480" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Hemangioma capilar retiniano yuxtapapilar bilateral: utilidad de aflibercept en el manejo de sus complicaciones" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1500 "Ancho" => 1500 "Tamanyo" => 222335 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">LE images after the first aflibercept injection: (a) retinograph, (d) angiograph, (g) OCT. After the 2nd injection: (b) retinograph, (e) angiograph, (h) OCT. After the 3rd injection: (c) retinograph, (f) angiograph, (i) OCT. Improvement is notable.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "R. Campos Polo, C. Rubio Sánchez, D.M. García Guisado, M.J. Díaz Luque" "autores" => array:4 [ 0 => array:2 [ "nombre" => "R." "apellidos" => "Campos Polo" ] 1 => array:2 [ "nombre" => "C." "apellidos" => "Rubio Sánchez" ] 2 => array:2 [ "nombre" => "D.M." "apellidos" => "García Guisado" ] 3 => array:2 [ "nombre" => "M.J." "apellidos" => "Díaz Luque" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S0365669117300278" "doi" => "10.1016/j.oftal.2016.12.015" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0365669117300278?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357941730141X?idApp=UINPBA00004N" "url" => "/21735794/0000009200000010/v1_201709270057/S217357941730141X/v1_201709270057/en/main.assets" ] "en" => array:20 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Short communication</span>" "titulo" => "Bilateral exudative retinal detachment associated with central serous chorioretinopathy in a patient treated with corticosteroids" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "481" "paginaFinal" => "485" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "T. Rueda-Rueda, J.L. Sánchez-Vicente, L. Llerena-Manzorro, A. Medina-Tapia, L. González-García, A. Alfaro-Juárez, C. Vital-Berral, F. López-Herrero, A. Muñoz-Morales, L.S. Ortega, Á. Herrador-Montiel" "autores" => array:11 [ 0 => array:2 [ "nombre" => "T." "apellidos" => "Rueda-Rueda" ] 1 => array:2 [ "nombre" => "J.L." "apellidos" => "Sánchez-Vicente" ] 2 => array:4 [ "nombre" => "L." "apellidos" => "Llerena-Manzorro" "email" => array:1 [ 0 => "laurall_1988@hotmail.com" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">*</span>" "identificador" => "cor0005" ] ] ] 3 => array:2 [ "nombre" => "A." "apellidos" => "Medina-Tapia" ] 4 => array:2 [ "nombre" => "L." "apellidos" => "González-García" ] 5 => array:2 [ "nombre" => "A." "apellidos" => "Alfaro-Juárez" ] 6 => array:2 [ "nombre" => "C." "apellidos" => "Vital-Berral" ] 7 => array:2 [ "nombre" => "F." "apellidos" => "López-Herrero" ] 8 => array:2 [ "nombre" => "A." "apellidos" => "Muñoz-Morales" ] 9 => array:2 [ "nombre" => "L.S." "apellidos" => "Ortega" ] 10 => array:2 [ "nombre" => "Á." "apellidos" => "Herrador-Montiel" ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Hospital Universitario Virgen del Rocío, Sevilla, Spain" "identificador" => "aff0005" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "<span class="elsevierStyleItalic">Corresponding author</span>." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Desprendimiento de retina exudativo bilateral asociado con coriorretinopatía serosa central en una paciente tratada con corticoesteroides" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0025" "etiqueta" => "Fig. 5" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr5.jpeg" "Alto" => 1208 "Ancho" => 2500 "Tamanyo" => 249452 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Final stage of 2 eyes. Intense subretinal fibrosis, RPE atrophy and hypertrophy and epiretinal membranes.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Central serous chorioretinopathy (CSC) is characterized by the presence of serous retinal detachment (SRD) or retina pigment epithelium detachment (RPED) generally limited to the macula and associated to the dissemination of liquid into the subretinal space.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">In typical CSC, SRD resolves spontaneously with visual recovery. However, atypical forms with bullous SRD associated to multiple large RPED can be confused with the Vogt–Koyanagi–Harada (VKH) disease.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">2</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">The case of a patient with chronic CSC erroneously diagnosed as VKH is presented. Systemic corticosteroid treatment worsened the condition with increased detachments and chronification of the disease. Discontinuation of corticosteroids was insufficient and it became necessary to surgically drain the subretinal fluid (SRF) through pars plana vitrectomy and the application of photodynamic therapy (PDT).</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Clinical case</span><p id="par0020" class="elsevierStylePara elsevierViewall">Female, 54, without relevant history, referred due to diminished vision with over 6 months evolution. Maximum uncorrected visual acuity was 0.25 in the right eye (RE) and 0.4 in the left eye (LE). Intraocular pressure and anterior chamber biomicroscopy were normal.</p><p id="par0025" class="elsevierStylePara elsevierViewall">In RE ocular fundus, the papilla exhibited normal color and was well defined. Diffuse macular edema with perimacular hemorrhages and retina pigment epithelium alterations could be observed. The LE exhibited a diffuse macular edema, notably the presence of 2 cystic formations adjacent to the superior temporal arch. Papilla was normal (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0030" class="elsevierStylePara elsevierViewall">Spectral domain optical coherence tomography (SD-OCT) (Topcon<span class="elsevierStyleSup">®</span> 3 D OCT-1000, Topcon Corporation, Tokyo, Japan) showed edema with large cysts in the RE central macula with SRF in the rest of the posterior pole. LE exhibited foveal neuroepithelium detachment with SRF in the entire posterior pole. Two larger cystic formations with RPED and SRF were observed adjacent to the superior arch (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>).</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0035" class="elsevierStylePara elsevierViewall">Fluorescein angiography evidenced diffuse retina pigment epithelium alterations in the RE, limited to posterior pole, with uneven hyperfluorescence. RPE hypertrophic areas could be observed together with stain accumulation areas. In the LE, the diffuse hyperfluorescence area was smaller, exhibiting 2 large areas of fluorescein accumulation corresponding to the cystic lesions in the superior temporal arch, as well as lesions compatible with RPED (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>).</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0040" class="elsevierStylePara elsevierViewall">The patient was diagnosed with VKH, beginning treatment with systemic corticosteroids and cyclosporine and referred to the Collagenosis and ENT Unit, discarding other associated systemic alterations.</p><p id="par0045" class="elsevierStylePara elsevierViewall">Hematimetry, biochemistry, serology and Mantoux were negative.</p><p id="par0050" class="elsevierStylePara elsevierViewall">The condition of the patient worsened and it was decided to adminster 3 intravenous bolus of corticosteroids (1<span class="elsevierStyleHsp" style=""></span>g methylprednisolone). After this treatment, the patient exhibited significant worsening with diminished VA (0.16 in RE and 0.032 in LE), the appearance of bullous SRD that compromised the inferior retina of both eyes (BE) (<a class="elsevierStyleCrossRef" href="#fig0020">Fig. 4</a>), which led to considering a diagnostic of chronic CSE. Corticosteroids and cyclosporine dosages were diminished prior to discontinuation.</p><elsevierMultimedia ident="fig0020"></elsevierMultimedia><p id="par0055" class="elsevierStylePara elsevierViewall">Due to SRD persistence in BE 8 weeks after discontinuing corticosteroid treatment that prevented laser treatment or PDT due to the height of the detachment, surgical drain was decided followed by bilateral PDT in different surgical interventions. Pars plana vitrectomy with 23<span class="elsevierStyleHsp" style=""></span>G was performed with liquid perfluorocarbon injection, external SRF drainage through 2 radial sclerostomies having a length of 3<span class="elsevierStyleHsp" style=""></span>mm, at 10<span class="elsevierStyleHsp" style=""></span>mm of the limbus on both sides of the medial rectus, intraocular laser in suspected diffusion areas and liquid-air-SF6 20% exchange.</p><p id="par0060" class="elsevierStylePara elsevierViewall">After reapplication of the retina, diminished fluency PDT was performed (25<span class="elsevierStyleHsp" style=""></span>J/cm<span class="elsevierStyleSup">2</span>) with normal dose of verteporfin (6<span class="elsevierStyleHsp" style=""></span>mg/m<span class="elsevierStyleSup">2</span>), during 83<span class="elsevierStyleHsp" style=""></span>s over an area of approximately 3000<span class="elsevierStyleHsp" style=""></span>μm corresponding to the diffusion areas, upon which the condition stabilized.</p><p id="par0065" class="elsevierStylePara elsevierViewall">At present, after 20 months follow-up, the corrected visual acuity of the patient is of 0.1 in the RE and 0.2 in the LE. The retina remains applied, with intense subretinal fibrosis with atrophy and hypertrophy of the retina pigment epithelium and macular epiretinal membranes in BE, possibly as a post-surgery complication (<a class="elsevierStyleCrossRef" href="#fig0025">Fig. 5</a>).</p><elsevierMultimedia ident="fig0025"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Discussion</span><p id="par0070" class="elsevierStylePara elsevierViewall">The association between corticosteroids and CSC is well-known. Patients with extended corticosteroid treatments could develop a chronic and recurring form of CSC.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">3</span></a> In addition, the use of steroids could worsen existing CSC and give rise to atypical forms such as diffuse epitheliopathy, bullous SRD and SRD with exudation and subretinal fibrosis.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">4</span></a> These forms could be confused with other entities, particularly VKH, which require the use of corticosteroids.</p><p id="par0075" class="elsevierStylePara elsevierViewall">The differential diagnostic of these atypical forms should include regmatogenous retina detachment, VKH, hypertensive choroidopathy, posterior scleritis, multifocal choroiditis, metastasis and the uveal effusion syndrome.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">2</span></a></p><p id="par0080" class="elsevierStylePara elsevierViewall">There are very few published cases reporting external drainage of SRF in patients with CSC and bullous SRD.<a class="elsevierStyleCrossRefs" href="#bib0070"><span class="elsevierStyleSup">5,6</span></a> Said procedure enabled flattening of the retina for adequate application of PDT. This treatment was preferred against other more conservative forms such as eplerenone or melatonin<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">7,8</span></a> or avoiding drainage sclerostomies,<a class="elsevierStyleCrossRef" href="#bib0090"><span class="elsevierStyleSup">9</span></a> due to the aggressiveness of the present case, the length of the evolution and the suspicion of high SRF density. Early drainage and PDT might have allowed better visual acuity preservation.</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conflict of interests</span><p id="par0085" class="elsevierStylePara elsevierViewall">No conflict of interests was declared by the authors.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:9 [ 0 => array:3 [ "identificador" => "xres906144" "titulo" => "Abstract" "secciones" => array:2 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Case report" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Discussion" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec886585" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres906143" "titulo" => "Resumen" "secciones" => array:2 [ 0 => array:2 [ "identificador" => "abst0015" "titulo" => "Caso clínico" ] 1 => array:2 [ "identificador" => "abst0020" "titulo" => "Discusión" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec886586" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:2 [ "identificador" => "sec0010" "titulo" => "Clinical case" ] 6 => array:2 [ "identificador" => "sec0015" "titulo" => "Discussion" ] 7 => array:2 [ "identificador" => "sec0020" "titulo" => "Conflict of interests" ] 8 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2016-07-25" "fechaAceptado" => "2017-01-10" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec886585" "palabras" => array:7 [ 0 => "Central serous chorioretinopathy" 1 => "Vogt–Koyanagi–Harada disease" 2 => "Exudative retinal detachment" 3 => "Corticosteroids" 4 => "Pars plana vitrectomy" 5 => "Subretinal liquid drainage" 6 => "Photodynamic therapy" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec886586" "palabras" => array:7 [ 0 => "Coriorretinopatía serosa central" 1 => "Enfermedad de Vogt-Koyanagi-Harada" 2 => "Desprendimiento exudativo de retina" 3 => "Corticoides" 4 => "Vitrectomía pars plana" 5 => "Drenaje de líquido subretiniano" 6 => "Terapia fotodinámica" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:3 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Case report</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The case is presented on a 54-year-old woman with a central serous chorioretinopathy, misdiagnosed as Vogt–Koyanagi–Harada disease, and treated with systemic corticosteroids. The patient presented with a bilateral bullous exudative retinal detachment.</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Discussion</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Discontinuation of corticosteroid therapy, surgical drainage of subretinal fluid, and photodynamic therapy, led to anatomical and functional improvement. The recognition of an atypical presentation of central serous chorioretinopathy may avoid complications of the inappropriate treatment with corticosteroids.</p></span>" "secciones" => array:2 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Case report" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Discussion" ] ] ] "es" => array:3 [ "titulo" => "Resumen" "resumen" => "<span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Caso clínico</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Presentamos el caso de una mujer de 54 años con una coriorretinopatía serosa central diagnosticada erróneamente de enfermedad de Vogt-Koyanagi-Harada y tratada con corticoides sistémicos. La paciente desarrolló un desprendimiento de retina exudativo bulloso en ambos ojos.</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Discusión</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">La interrupción del tratamiento con corticoides junto con el drenaje quirúrgico del líquido subretiniano y la aplicación de terapia fotodinámica consiguió la mejoría anatómica y funcional. El correcto diagnóstico de las formas atípicas de la enfermedad podría evitar las complicaciones del uso inadecuado de los corticoides.</p></span>" "secciones" => array:2 [ 0 => array:2 [ "identificador" => "abst0015" "titulo" => "Caso clínico" ] 1 => array:2 [ "identificador" => "abst0020" "titulo" => "Discusión" ] ] ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Rueda-Rueda T, Sánchez-Vicente JL, Llerena-Manzorro L, Medina-Tapia A, González-García L, Alfaro-Juárez A, et al. Desprendimiento de retina exudativo bilateral asociado con coriorretinopatía serosa central en una paciente tratada con corticoesteroides. Arch Soc Esp Oftalmol. 2017;92:481–485.</p>" ] ] "multimedia" => array:5 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 617 "Ancho" => 1500 "Tamanyo" => 115820 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">(a) RE retinograph: diffuse macular edema with perimacular hemorrhages and retina pigment epithelium alterations. (b) LE retinograph: macular edema and cystic formations next to the superior temporal arch.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1568 "Ancho" => 1600 "Tamanyo" => 296890 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">RE OCT: edema with large cysts in the central macula with presence of subretinal fluid in the rest of the posterior pole. LE OCT: foveal neuroepithelium detachment with subretinal fluid throughout the posterior pole.</p>" ] ] 2 => array:7 [ "identificador" => "fig0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 1826 "Ancho" => 2667 "Tamanyo" => 407305 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Early and late fluorescein angiography of both eyes.</p>" ] ] 3 => array:7 [ "identificador" => "fig0020" "etiqueta" => "Fig. 4" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr4.jpeg" "Alto" => 2210 "Ancho" => 1658 "Tamanyo" => 242523 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Fluorescein angiography. Large bullous detachment of the inferior retina of both eyes.</p>" ] ] 4 => array:7 [ "identificador" => "fig0025" "etiqueta" => "Fig. 5" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr5.jpeg" "Alto" => 1208 "Ancho" => 2500 "Tamanyo" => 249452 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Final stage of 2 eyes. Intense subretinal fibrosis, RPE atrophy and hypertrophy and epiretinal membranes.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:9 [ 0 => array:3 [ "identificador" => "bib0050" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Central serous chorioretinopathy: update on pathophysiology and treatment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "B. Nicholson" 1 => "J. Noble" 2 => "F. Forooghian" 3 => "C. Meyerle" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.survophthal.2012.07.004" "Revista" => array:6 [ "tituloSerie" => "Surv Ophthalmol" "fecha" => "2013" "volumen" => "58" "paginaInicial" => "103" "paginaFinal" => "126" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23410821" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0055" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical management of bilateral exudative retinal detachment associated with central serous chorioretinopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "J.E. Kang" 1 => "H.J. Kim" 2 => "H.D. Boo" 3 => "H.K. Kim" 4 => "J.H. Lee" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.3341/kjo.2006.20.2.131" "Revista" => array:7 [ "tituloSerie" => "Korean J Ophthalmol" "fecha" => "2006" "volumen" => "20" "paginaInicial" => "131" "paginaFinal" => "138" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16892652" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0886335012012850" "estado" => "S300" "issn" => "08863350" ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0060" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Can long-term corticosteroids lead to blindness? A case series of central serous chorioretinopathy induced by corticosteroids" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "J.L. Loo" 1 => "S.Y. Lee" 2 => "C.L. Ang" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:7 [ "tituloSerie" => "Ann Acad Med Singapore" "fecha" => "2006" "volumen" => "35" "paginaInicial" => "496" "paginaFinal" => "499" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16902727" "web" => "Medline" ] ] "itemHostRev" => array:3 [ "pii" => "S0886335014015272" "estado" => "S300" "issn" => "08863350" ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0065" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Central serous chorioretinopathy and glucocorticoids" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "E.A. Bouzas" 1 => "P. Karadimas" 2 => "C.J. Pournaras" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Surv Ophthalmol" "fecha" => "2002" "volumen" => "47" "paginaInicial" => "431" "paginaFinal" => "448" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12431693" "web" => "Medline" ] ] ] ] ] ] ] ] 4 => array:3 [ "identificador" => "bib0070" "etiqueta" => "5" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Surgical management of exudative retinal detachment associated with central serous chorioretinopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "A. Adán" 1 => "B. Corcóstegui" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "50831" "Revista" => array:6 [ "tituloSerie" => "Ophthalmologica" "fecha" => "2001" "volumen" => "215" "paginaInicial" => "74" "paginaFinal" => "76" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11125275" "web" => "Medline" ] ] ] ] ] ] ] ] 5 => array:3 [ "identificador" => "bib0075" "etiqueta" => "6" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Perfluorocarbon liquid-assisted external drainage in the management of central serous chorioretinopathy with bullous serous retinal detachment" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "H.C. Chen" 1 => "J.D. Ho" 2 => "S.N. Chen" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Chang Gung Med J" "fecha" => "2003" "volumen" => "26" "paginaInicial" => "777" "paginaFinal" => "781" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14717214" "web" => "Medline" ] ] ] ] ] ] ] ] 6 => array:3 [ "identificador" => "bib0080" "etiqueta" => "7" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Eplerenone treatment in chronic central serous chorioretinopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "M. Sampo" 1 => "V. Soler" 2 => "P. Gascon" 3 => "G. Ho Wang Yin" 4 => "L. Hoffart" 5 => "D. Denis" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.jfo.2016.01.008" "Revista" => array:6 [ "tituloSerie" => "J Fr Ophtalmol" "fecha" => "2016" "volumen" => "39" "paginaInicial" => "535" "paginaFinal" => "542" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/27230892" "web" => "Medline" ] ] ] ] ] ] ] ] 7 => array:3 [ "identificador" => "bib0085" "etiqueta" => "8" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Therapeutic benefit of melatonin in refractory central serous chorioretinopathy" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "A.L. Gramajo" 1 => "G.E. Marquez" 2 => "V.E. Torres" 3 => "C.P. Juárez" 4 => "R.E. Rosenstein" 5 => "J.D. Luna" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Eye (Lond)" "fecha" => "2015" "volumen" => "29" "paginaInicial" => "1036" "paginaFinal" => "1045" "itemHostRev" => array:3 [ "pii" => "S0886335016302589" "estado" => "S300" "issn" => "08863350" ] ] ] ] ] ] ] 8 => array:3 [ "identificador" => "bib0090" "etiqueta" => "9" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bullous retinal detachment in chronic central serous chorioretinopathy treated with photodynamic therapy" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "L. Arias" 1 => "R. Alcubierre" 2 => "D. Lorenzo" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.oftal.2010.11.017" "Revista" => array:6 [ "tituloSerie" => "Arch Soc Esp Oftalmol" "fecha" => "2011" "volumen" => "86" "paginaInicial" => "58" "paginaFinal" => "61" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21440832" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735794/0000009200000010/v1_201709270057/S2173579417301068/v1_201709270057/en/main.assets" "Apartado" => array:4 [ "identificador" => "5812" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Short communications" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735794/0000009200000010/v1_201709270057/S2173579417301068/v1_201709270057/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173579417301068?idApp=UINPBA00004N" ]
| Year/Month | Html | Total | |
|---|---|---|---|
| 2023 March | 1 | 0 | 1 |
| 2020 September | 0 | 1 | 1 |
