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Letter to the Editor
Immune audit of COVID-19 at the department of ophthalmology of a tertiary hospital before deconfinement
Auditoría inmunitaria de COVID-19 en el servicio de oftalmología de un hospital de tercer nivel antes del desconfinamiento
A.M. Garrido-Hermosillaa,b,
Corresponding author
gaherfamily@hotmail.com

Corresponding author.
, M. Caro-Magdalenoa,b, J.F. Moreno-Galdoa,b, E. Rodríguez-de-la-Rúa-Francha,b
a Unidad de Gestión Clínica de Oftalmología, Hospital Universitario Virgen Macarena, Sevilla, Spain
b RETICS OftaRed, Instituto de Salud Carlos III, Madrid, Spain
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known as &#8220;descaling&#8221;&#44; &#40;an English-language term that is not approved by the Royal Academy of the Spanish Language&#41; for existing healthcare conditions&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">However&#44; it is well-known that accessibility to SARS-CoV-2 tests &#40;severe acute respiratory syndrome coronavirus 2&#41;&#44; the virus that has caused COVID-19&#44; has been and continues to be limited for health professionals&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">In these circumstances&#44; in our department we have personally purchased 40 VivaDiag<span class="elsevierStyleSup">TM</span> quick tests for COVID-19 IgM&#47;IgG &#40;VivaChek&#8482; Biotech Co&#46;&#44; Ltd&#46;&#44; Hangzhou&#44; China&#41;&#46; This test makes a qualitative assessment of IgM and IgG antibodies against SARS-CoV-2&#46; The cost of this test is low and it is very simple to make&#44; as can be seen in <a class="elsevierStyleCrossRef" href="#fig0005">Figure 1</a>A &#46; No equipment is necessary to assess the results of the test&#44; which can be read in 15<span class="elsevierStyleHsp" style=""></span>min &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46; In what concerns diagnostic reliability&#44; the manufacturers report a specificity of 100&#37; and sensitivity of 81&#46;25&#37; between day 4 and day 10 of the infection&#44; and 97&#46;1&#37; between between days 11 and 24<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a>&#46; However&#44; as indicated by the website of the Health Ministry&#44; the National Microbiology Center has assessed the reliability of this test with samples of patients from hospitals in different regions of Spain&#44; and confirm 100&#37; specificity as reported by the lab but lower sensitivity &#40;64&#37;&#41; when applied to patients without taking into account evolution time&#44; and of approximately 80&#37; in patients with over 7 days evolution of the disease<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a>&#46; The main drawback of these quick tests is that they are not useful during the first days of infection because antibodies against virus start being produced as from day 6 since the onset of symptoms<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a>&#46; Therefore&#44; it would be convenient to combine this test with the polymerase chain reaction &#40;PCR&#41; which continues to be the reference diagnostic test&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">The study initiated by our department had 2 main objectives&#58; to determine whether an ophthalmologist in the department&#44; none of whom had symptoms&#44; was an asymptomatic case&#44; and also to determine whether anyone had endured the infection asymptomatically and was immune to the virus&#46; The idea was to plan clinic and surgical care strategies for the future&#46; None of the 40 tested ophthalmologists was positive for IgM and&#47;or IgG&#46; This result was verified by 2 ophthalmologists of our department&#44; obviously not those who were tested&#44; utilizing a certification record specifically designed for the purpose &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>C&#41;&#46;</p><p id="par0030" class="elsevierStylePara elsevierViewall">In the light of the results of this study&#44; it is clear that we should continue maintaining safety measures in our healthcare practice&#44; both in consultations and surgery rooms&#44; at least until an effective vaccine becomes available&#46; Consequently&#44; we call on ophthalmologists who have not yet tested their immunity against the virus to do so at the earliest possible time&#44; particularly if they work in the regions that are most affected by the pandemic&#46; Let us remain steadfast&#44; we shall prevail&#46;</p></span>"
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Article information
ISSN: 21735794
Original language: English
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es en pt

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Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos