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Resumen
El tratamiento adyuvante y neoadyuvante del cáncer de esófago es un tema que sigue siendo controvertido. Los ensayos realizados en las últimas 2 décadas han permitido aclarar algunos conceptos y marcar las futuras líneas de trabajo e investigación. Mientras el tratamiento adyuvante va perdiendo fuerza, el neoadyuvante demuestra ser prometedor. A falta de los resultados de los ensayos en curso, se ha demostrado efectivo en el control local de la enfermedad, en la disminución de las recidivas y, en algún caso, en la supervivencia postoperatoria.
Se efectúa una revisión de los principales trabajos hasta la actualidad y se marcan las líneas de trabajo en un futuro inmediato.
Palabras clave:
Cáncer de esófago
Tratamiento adyuvante
neoadyuvante
Adjuvant and neoadjuvant therapy of esophageal cancer remains controversial. The trials performed in the last decade have elucidated certain concepts and defined future areas of research. While adjuvant therapy is falling out of favor, neoadjuvant therapy is promising. Although the results of current trials are lacking, this therapy has been shown to be effective in local control of the disease, reduction of recurrence and, in certain cases, in postoperative survival.
We review the main studies published to date and end by outlining research areas in the immediate future.
Key words:
Esoghageal cancer
Adjuvant
neoadjuvant therapy
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