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Inicio Cirugía Española VIPoma pancreático: aportación de dos casos con diferente malignidad
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Vol. 74. Issue 4.
Pages 239-241 (October 2003)
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Vol. 74. Issue 4.
Pages 239-241 (October 2003)
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VIPoma pancreático: aportación de dos casos con diferente malignidad
Pancreatic vipoma: Report of one benign and one malignant case
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Christian Muñoz-Guijosaaa,1
Corresponding author
cmunozg@hsp.santpau.es

Correspondencia: Dr. C. Muñoz-Guijosa. Pge. Flaugier, 19 ático 2.a. 08041 Barcelona. España.
, Antonio Moralaa, Ángela Hernándeza, F. Josep Sanchob, Vicente Artigasaa, Manuel Triasaa
a Servicio de Cirugía General y Digestiva. Hospital de la Santa Creu i Sant Pau. Universidad Autónoma de Barcelona. Barcelona. España.
b Servicio de Anatomía Patológica. Hospital de la Santa Creu i Sant Pau. Universidad Autónoma de Barcelona. Barcelona. España.
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Resumen

El VIPoma es un tumor neuroendocrino, de muy baja incidencia, localizado la mayoría de los casos en el páncreas, que provoca la hipersecreción de péptido intestinal vasoactivo (VIP). Se describen dos casos, que tras presentar un cuadro clínico de diarrea de larga evolución, fueron diagnosticados de VIPoma pancreático, procediéndose a su resección quirúrgica. Su estudio posterior permitió comprobar la histología benigna de uno de los casos y la maligna del otro.

Plabras clave:
VIPoma
Tumor pancreático
Tumor neuroendocrino
Péptido intestinal vasoactivo

VIPoma is a rare neuroendocrine tumor that secretes vasoactive intestinal polypeptide. It is usually located in the pancreas. We describe two patients with long-term diarrhea who were diagnosed with pancreatic vipoma. Tumor resection was performed. Subsequent study revealed that one tumor was benign and the other was malignant.

Key words:
VIPoma
Pancreatic neoplasm
Neuroendocrine tumour
Vasoactive intestinal polypeptide
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Bibliografía
[1.]
J.V. Verner, A.B. Morrison.
Islet cell tumor and a syndrome of refractory diarrea and hypokaliemia.
Am J Med, 25 (1958), pp. 374-380
[2.]
S.K. Park, M.S. O‘Dorisio, T.M. O‘Dorisio.
Vasoactive intestinal polypeptide- secreting tumors: biology and therapy.
Baillieres Clin Gastroenterol, 10 (1996), pp. 673-696
[3.]
T.M. O‘Dorisio, M.S. Mekhjian, T.S. Gaginella.
Medical therapy of VIPomas.
Endocrinol Metab Clin North Am, 18 (1989), pp. 545
[4.]
G.J. Krejs, J.S. Fordtran, J. Fahrenkrug, O.B. Schaffalitzky de Muckadell, J.E. Fisher, C.S. Humphrey, et al.
Effect of VIP infusion in water and ion transport in the human jejunum.
Gastroenterol, 4 (1980), pp. 722-727
[5.]
F. Bermejo, L. Moreno, V. Moreira, J.P. Gisbert, F. González, J.L. García.
VIPoma pancreático con características atípicas.
Gastroenterol Hepatol, 22 (1999), pp. 132-135
[6.]
K.J. Moriarty, J.E. Hegarty, K. Tatemoto, V. Mutt, N.D. Christofides, S.R. Bloom, et al.
Effect of peptide histidine isoleucine on water and electrolyte transport in the human jejunum.
Gut, 25 (1984), pp. 624-628
[7.]
S.R. Bloom.
Vasoactive intestinal peptide, the major mediator of the WDHA (pancreatic cholera) syndrome: value of measurement in diagnosis and treatment.
Dig Dis Sci, 23 (1978), pp. 373-376
[8.]
Y. Krausz, J. Bar-Ziv, R.B. De Jong, S. Ish-Shalom, R. Chisin, N. Shibley, et al.
Somatostain-receptor scintigraphy in the management of gastroenteropancreatic tumors.
Am J Gastroenterol, 93 (1998), pp. 66-70
[9.]
R. Brentjens, L. Saltz.
Islet cell tumors of the pancreas: the medical oncologist‘s perspective.
Surg Clin North Am, 81 (2001), pp. 527-542
[10.]
M.C. Aldridge.
Islet cell tumours: surgical treatment.
Hosp Med, 61 (2000), pp. 830-833
[11.]
H.N. Nguyen, B. Backes, F. Lammert, J. Wildberger, R. Winogard, N. Busch, et al.
Long-term survival after diagnosis of hepatic metastasic VIPoma: report of two cases with disparate courses and review of therapeutic options.
Dig Dis Sci, 44 (1999), pp. 1148-1155
Copyright © 2003. Asociación Española de Cirujanos
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