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D) EDA (paciente 3): lesión subcardial de probable origen mucoso.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Alba Manuel Vázquez, Alberto Hernández Matías, Agustín Bertomeu García, Juan Carlos Ruiz de Adana Belbel" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Alba" "apellidos" => "Manuel Vázquez" ] 1 => array:2 [ "nombre" => "Alberto" "apellidos" => "Hernández Matías" ] 2 => array:2 [ "nombre" => "Agustín" "apellidos" => "Bertomeu García" ] 3 => array:2 [ "nombre" => "Juan Carlos" "apellidos" => "Ruiz de Adana Belbel" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2173507716000715" "doi" => "10.1016/j.cireng.2016.02.017" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => 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Courvoisier Gallbladder" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "179" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Carcinomatosis peritoneal y vesícula de Courvoisier" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 754 "Ancho" => 1200 "Tamanyo" => 200497 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Ismael Mora-Guzmán, José Luis Muñoz de Nova, Paloma Largo Flores, Jesús Delgado Valdueza" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Ismael" "apellidos" => "Mora-Guzmán" ] 1 => array:2 [ "nombre" => "José Luis" "apellidos" => "Muñoz de Nova" ] 2 => array:2 [ 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"article" "crossmark" => 1 "subdocumento" => "fla" "cita" => "Cir Esp. 2016;94:165-74" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 827 "formatos" => array:3 [ "EPUB" => 9 "HTML" => 650 "PDF" => 168 ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Original article</span>" "titulo" => "Usefulness of Administrative Databases for Risk Adjustment of Adverse Events in Surgical Patients" "tienePdf" => "en" "tieneTextoCompleto" => "en" "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "165" "paginaFinal" => "174" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Validez de las bases de datos administrativas para realizar ajustes de riesgo en el análisis de los efectos adversos producidos en pacientes quirúrgicos" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1591 "Ancho" => 2992 "Tamanyo" => 210033 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">The validity of the MBSD in comparison with CH in the detection of comorbidities in surgical patients. Sensitivity and positive predictive value along the axis. Bubble size depends on comorbidity frequency.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Isabel Rodrigo-Rincón, Marta P. Martin-Vizcaíno, Belén Tirapu-León, Pedro Zabalza-López, Francisco J. Abad-Vicente, Asunción Merino-Peralta, Fabiola Oteiza-Martínez" "autores" => array:7 [ 0 => array:2 [ "nombre" => "Isabel" "apellidos" => "Rodrigo-Rincón" ] 1 => array:2 [ "nombre" => "Marta P." "apellidos" => "Martin-Vizcaíno" ] 2 => array:2 [ "nombre" => "Belén" "apellidos" => "Tirapu-León" ] 3 => array:2 [ "nombre" => "Pedro" "apellidos" => "Zabalza-López" ] 4 => array:2 [ "nombre" => "Francisco J." 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The choice of technique depends on the size, location and growth type of the lesion. Developments made in minimally invasive surgery and technological advances have led us to explore new approaches to overcome the difficulties found in traditional laparoscopy.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Possible indications for these new techniques would be gastric lesions that, due to their location, size or thickness, are not resectable by endoscopy, as well as those that require extensive gastrotomies or those that are located in a complicated region, such as the oesophagogastric junction (OGJ).</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Surgical Technique</span><p id="par0015" class="elsevierStylePara elsevierViewall">Below, we review our experience with an intragastric laparoscopic approach in 3 consecutive patients. All the patients were informed about the details of the procedure they were to undergo, as well as the fact that they would be the first cases.</p><p id="par0020" class="elsevierStylePara elsevierViewall">Indication for the procedure was determined by the presence of gastric, mucosal or submucosal lesions that were noncancerous, proximal to the OGJ and endoscopically unresectable.</p><p id="par0025" class="elsevierStylePara elsevierViewall">In all the cases, prior to the placement of 3 trocars in the peritoneal cavity, another 3 trocars with balloons were inserted in the interior of the stomach in the area of the gastric body. Once the lesion was located, the submucosa was infiltrated with adrenalin and resected, including the entire thickness of the wall, with an ultrasonic scalpel. The wall defect was closed with a manual suture in 2 planes, and the specimen was extracted through one of the gastrotomies.</p><p id="par0030" class="elsevierStylePara elsevierViewall">One of the disadvantages of this procedure is the loss of “gastroperitoneum” when the gastric wall is opened. In the case of lesions situated on the posterior gastric side, there was no gas leak to the peritoneal cavity because the lesion was located in the retroperitoneal gastric portion. On the contrary, when the serosa was opened in an intraperitoneal area and the stomach collapsed from the pressure of the pneumoperitoneum, we were able to recover the gastric distension by opening one of the trocars located in the peritoneal cavity (not one of the intragastric ones) and increasing the gas flow into the stomach.</p><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Patient 1</span><p id="par0035" class="elsevierStylePara elsevierViewall">A 77-year-old woman underwent oesophagogastroduodenoscopy (OGD), which had detected a submucosal lesion measuring 3.5<span class="elsevierStyleHsp" style=""></span>cm in the gastric fundus (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A and B). Intragastric resection was carried out with 3 trocars following the previously described technique. The histology study confirmed it as a gastrointestinal stromal tumour (GIST) measuring 4<span class="elsevierStyleHsp" style=""></span>cm×2.2<span class="elsevierStyleHsp" style=""></span>cm×1.5<span class="elsevierStyleHsp" style=""></span>cm that was well differentiated, very low risk and had free margins (pT2). The patient was discharged on the 5th day post-op with no complications.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Patient 2</span><p id="par0040" class="elsevierStylePara elsevierViewall">In a 71-year-old woman, OGD identified a 7-cm polyp with lateral growth that was vegetative and situated in the infracardiac region. Biopsy was compatible with a hyperplastic polyp with low-grade dysplasia (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>C). Intragastric resection was performed of a polypoid lesion measuring 10<span class="elsevierStyleHsp" style=""></span>cm×5<span class="elsevierStyleHsp" style=""></span>cm×3<span class="elsevierStyleHsp" style=""></span>cm. The histology study confirmed a hyperplastic polyp with foci of low-grade dysplasia and free surgical margins. The patient was discharged on the 7th day post-op without incident.</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Patient 3</span><p id="par0045" class="elsevierStylePara elsevierViewall">OGD diagnosed an infracardiac semi-pedunculated lesion in a 70-year-old male that measured 3<span class="elsevierStyleHsp" style=""></span>cm and was probably submucosal in origin (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>D). Intragastric resection was done of the submucosal tumour and the histopathology defined it as a 4<span class="elsevierStyleHsp" style=""></span>cm GIST with free margins and moderate risk (pT2) (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). The patient was discharged on the 5th post-op day without complications.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Discussion</span><p id="par0050" class="elsevierStylePara elsevierViewall">Since its initial description by Ohashi in 1995,<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> intragastric laparoscopic surgery has provided an additional option for the approach of gastric lesions, both mucosal as well as submucosal, which are not endoscopically resectable.</p><p id="par0055" class="elsevierStylePara elsevierViewall">In the case of endophytic lesions proximal to the OGJ or located at the posterior side of the stomach, it may be necessary to resect this junction, which can have long-term digestive consequences due to stenosis or postoperative deformities. In addition, these procedures are associated with considerably increased morbidity and mortality, even in expert hands.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> The location and type of growth observed on OGD are fundamental for establishing surgical indication.<a class="elsevierStyleCrossRefs" href="#bib0040"><span class="elsevierStyleSup">2–4</span></a></p><p id="par0060" class="elsevierStylePara elsevierViewall">In our opinion, this is most useful in 2 situations: (1) lesions that are proximal to the OGJ, whose excision by laparotomy or conventional laparoscopy would necessitate extensive gastrotomy very close to this junction, or may even require resection; (2) lesions with submucosal growth in the upper part of the posterior side of the stomach, which would equally require extensive gastrotomy.</p><p id="par0065" class="elsevierStylePara elsevierViewall">Size can be a limitation in this type of intervention when extracting the surgical specimen through the incision in the stomach, but this is basically due to the possible deformity of the OGJ after closure of a large defect. In our series, the largest surgical specimen was 10<span class="elsevierStyleHsp" style=""></span>cm, which corresponded with a polyp that was extracted by widening one of the gastrotomies and the skin incision. This increased the surgical time and may increase the morbidity related with the technique, although it is still probably lower than the morbidity associated with conventional OGJ surgery.</p><p id="par0070" class="elsevierStylePara elsevierViewall">The advantage in intragastric surgery is obtained with a distended stomach, which allows the surgeon to manoeuvre close to the lesion with relative ease and to conduct gastrotomies far from the OGJ, although accessing it easily. The technique with several intragastric trocars, as described in our series, provides good visualisation and optimal triangulation of the instruments, which facilitates suturing for closure of the defect.</p><p id="par0075" class="elsevierStylePara elsevierViewall">Other techniques have been reported for the intragastric approach, such as single-port<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a> (whose main limitation is the lack of triangulation, which makes the technique more difficult) or intragastric stapling<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a> (which is a rapid technique that minimises the risk of gastric perforation associated with resection using electronic instruments). The latter technique requires special care to achieve free resection margins, which is an essential point in GIST and in tumours of uncertain benign nature, which is practically impossible to achieve proximal to the OGJ.</p><p id="par0080" class="elsevierStylePara elsevierViewall">In order to achieve optimal access of the OGJ, the trocars should be situated in accordance with the principles of general laparoscopy where, when compressed with a hand, the abdominal wall is in contact with the anterior gastric wall, and at least 3<span class="elsevierStyleHsp" style=""></span>cm apart.<a class="elsevierStyleCrossRef" href="#bib0055"><span class="elsevierStyleSup">5</span></a> After exeresis of the lesion, the suture of the defect versus the absence of closure described in the initial technique<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> has demonstrated faster healing of the mucosa and a decrease in postoperative use of proton pump inhibitors.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">6</span></a></p><p id="par0085" class="elsevierStylePara elsevierViewall">There is some controversy about the need for OGD during intragastric resection, since some published articles consider it necessary to locate the lesion, insert ports, assist intragastric resection, extract the specimen through the mouth and test the resection area.<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a> In our case series, this was not necessary because the lesions were clearly identified during the operation and the extraction of the specimens was done through one of the gastrotomies used for the insertion of the trocars.</p><p id="par0090" class="elsevierStylePara elsevierViewall">Therefore, the intragastric laparoscopic approach provides for the excision of mucosal or submucosal lesions, either benign or premalignant, that are not endoscopically resectable. This type of resection is another approach in the arsenal of minimally invasive surgery that can provide advantages over traditional laparoscopy, such as avoiding resection of the OGJ in proximal lesions as well as extensive gastric resections in posterior gastric wall lesions, and diminished morbidity associated with these procedures.<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a></p><p id="par0095" class="elsevierStylePara elsevierViewall">We put forth our initial surgical experience with this innovative technique in 3 consecutive cases that were satisfactorily resolved by taking advantage of the benefits of minimally invasive surgery. However, more extensive studies would be necessary to compare it with conventional surgical procedures and assess possible limitations for its indications, especially in terms of size. These studies can be difficult to conduct due to the low prevalence of this type of lesions.</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Conflict of Interests</span><p id="par0100" class="elsevierStylePara elsevierViewall">The authors have no conflict of interests to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:9 [ 0 => array:3 [ "identificador" => "xres621299" "titulo" => "Abstract" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0005" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec635551" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres621300" "titulo" => "Resumen" "secciones" => array:1 [ 0 => array:1 [ "identificador" => "abst0010" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec635550" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:3 [ "identificador" => "sec0010" "titulo" => "Surgical Technique" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0015" "titulo" => "Patient 1" ] 1 => array:2 [ "identificador" => "sec0020" "titulo" => "Patient 2" ] 2 => array:2 [ "identificador" => "sec0025" "titulo" => "Patient 3" ] ] ] 6 => array:2 [ "identificador" => "sec0030" "titulo" => "Discussion" ] 7 => array:2 [ "identificador" => "sec0035" "titulo" => "Conflict of Interests" ] 8 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2015-06-17" "fechaAceptado" => "2015-11-03" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec635551" "palabras" => array:4 [ 0 => "Laparoscopic intragastric surgery" 1 => "Minimally invasive gastric surgery" 2 => "Benign gastric lesion" 3 => "Esophagogastric junction" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec635550" "palabras" => array:4 [ 0 => "Cirugía laparoscópica intragástrica" 1 => "Cirugía gástrica mínimamente invasiva" 2 => "Lesión gástrica benigna" 3 => "Unión esofagogástrica" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Gastric mucosal and submucosal lesions can be resected by endoscopy, laparoscopy or open surgery. Operative methods have varied depending on the location, endophytic growth and size of the lesion.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Interest in minimally invasive surgery has increased and many surgeons are attempting laparoscopic approaches, especially in lesions of the stomach near the esophagogastric junction not amendable to endoscopic removal, because conventional surgery can produce stenosis and distort the postoperative anatomy, and increase morbimortality.</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We report our experience with laparoscopic intragastric surgery in 3 consecutive patients, with no complications.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Laparoscopic intragastric surgery extends the surgeons’ armamentarium to resect complex gastric lesions, while offering patients the benefits of minimal access surgery.</p></span>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Las lesiones mucosas y submucosas gástricas pueden abordarse por vía endoscópica, laparoscópica o por cirugía abierta. El tamaño, la localización y el tipo de crecimiento son determinantes a la hora de la elección de la técnica.</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">El interés en la cirugía mínimamente invasiva ha llevado a desarrollar nuevos abordajes para suplir las dificultades de la laparoscopia tradicional, como puede ser el caso de la resección de lesiones próximas a la unión esofagogástrica no resecables endoscópicamente, donde la cirugía convencional puede producir estenosis o deformidades posoperatorias y aumento de la morbimortalidad.</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Presentamos nuestra experiencia en el abordaje de este tipo de lesiones mediante cirugía laparoscópica intragástrica en 3 pacientes consecutivos, con resultado satisfactorio.</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Este tipo de intervención supone un abordaje más en el arsenal de la cirugía mínimamente invasiva, que puede proporcionar ventajas frente a la cirugía tradicional.</p></span>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Manuel Vázquez A, Hernández Matías A, Bertomeu García A, Ruiz de Adana Belbel JC. Cirugía laparoscópica intragástrica: una opción en lesiones gástricas no resecables endoscópicamente. Cir Esp. 2016;94:175–178.</p>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1279 "Ancho" => 1500 "Tamanyo" => 271844 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">(A and B) Oesophagogastroduodenoscopy (patient 1): submucosal lesion in gastric fundus compatible with GIST; (C) OGD (patient 2): predominantly exophytic polyp in the infracardiac region; (D) OGD (patient 3): infracardiac lesion of probable mucosal origin.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 928 "Ancho" => 1900 "Tamanyo" => 488883 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">Surgical intervention of patient 3: (A) placement of intragastric trocars; (B) image of the lesion; (C) identification of the OGJ; (D) resection with harmonic scalpel of the lesion; (E) full-thickness defect after exeresis; (F) defect closure.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:6 [ 0 => array:3 [ "identificador" => "bib0035" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Laparoscopic intraluminal (intragastric) surgery for early gastric cancer. A new concept in laparoscopic surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "S. Ohashi" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:6 [ "tituloSerie" => "Surg Endosc" "fecha" => "1995" "volumen" => "9" "paginaInicial" => "169" "paginaFinal" => "171" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/7597587" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0040" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Techniques of intragastric laparoscopic surgery" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "C. Conrad" 1 => "M. Nedelcu" 2 => "S. Ogiso" 3 => "T.A. Aloia" 4 => "J.N. Vauthey" 5 => "B. 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