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He reported lower back pain with no evident toxic symptoms. On examination, a hard umbilical mass was observed with seropurulent discharge (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Computed tomography revealed a pancreatic tumor with extensive local invasion (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>), as well as peritoneal carcinomatosis with multiple implants, one in the umbilical region. The pathology results of the umbilical nodule identified adenocarcinoma of pancreatic–biliary origin, which confirmed the diagnosis of Sister Mary Joseph's nodule. After evaluation by the multidisciplinary committee, treatment with palliative chemotherapy was started.</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Capdevila B, Guasch M, Sebastián-Valverde E, Gris P. Nódulo de la hermana María José como presentación inicial de adenocarcinoma pancreático. 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