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Editorial
“2024 Spanish Society of Arteriosclerosis standards for the global control of vascular risk: an essential reference document”
Fernando Civeiraa,
Corresponding author
civeira@unizar.es

Corresponding author.
, Rosa M. Sánchez-Hernándezb
a Servicio de Medicina Interna, Hospital Universitario Miguel Servet, IIS Aragón, CIBER Cardiovascular, Universidad de Zaragoza, Zaragoza, Spain
b Secciónde Endocrinología y Nutrición, Complejo Hospitalario Universitario Insular Materno-Infantil, Instituto de Investigaciones Biomédicas y Sanitarias (IUIBS), Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">According to the Royal Spanish Academy&#44; the word standard is &#8220;that which serves as a type&#44; model&#44; norm&#44; pattern or reference&#46;&#8221; I believe that the authors of the document&#44; which we have the pleasure of commenting on in this leading article&#44; could not have headed it more precisely&#46; The prevention of cardiovascular diseases is one of the most effective tools for the preservation and optimisation of health and opportunities for lengthening the general publics&#8217; good quality life&#46; The document summarises&#44; updates and clearly explains the model required to do this&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">Life expectancy at birth in Spain has increased more than 10 years for both sexes since 1980&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> The decrease in mortality from cardiovascular diseases contributes to this increase by 63&#37; among women and 53&#37; among men&#46; In ages &#8805;65 years&#44; the contribution is 93&#37; and 87&#37; of the total respectively&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> This means that cardiovascular disease prevention is mainly responsible for us living longer and better&#44; and that the efforts that the different cardiovascular prevention measures have involved at an individual and collective level are highly effective&#46; We live longer and our life is higher in quality&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> These statistics may be interpreted in different ways&#46; The first is very positive&#58; we are on the right path&#46; We know the aetiopathogenesis of most cardiovascular diseases&#59; we have effective tools for their treatment which are safe and cost-effective&#44; and if these tools are correctly applied to large strata of the population&#44; atheromatous cardiovascular disease could disappear in a few decades&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">On the negative side is the fact that we are improving too slowly&#46; For this reason&#44; cardiovascular morbidity and mortality continue to be one of the main causes of death and disability in Spain and surrounding countries&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> How can we explain this paradox&#63; It seems contrary to logic that&#44; with the knowledge and means to avoid this group of devastating diseases&#44; cardiovascular diseases still account for a quarter of total mortality in Spain&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">There are many reasons to explain this paradox&#46; Among them is that we probably apply preventive measures too late&#44; when the clinical or subclinical disease is already advanced and where therapeutic possibilities are fewer&#46; Observational studies tell us that if we applied these measures at earlier ages&#44; the benefit could be multiplied&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> Also significant is the Spanish healthcare model&#46; It focuses very highly on disease treatment&#44; whether acute or chronic&#44; with excellent hospitals and health centres that devote their efforts to treating the disease in advanced stages&#44; and sometimes in the final stages of life when little remains to be done from a medical point of view&#46; In Spain&#44; health spending per inhabitant is concentrated in the final years of life&#44; and annual spending before the age of 60 represents a small percentage of total spending throughout life&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">7</span></a> We spend the budget on older ages and in the phases of advanced illness when healing is difficult and life expectancy is shorter&#46; This means that there is a prevention deficit in the Spanish system&#46; The Spanish Society of Arteriosclerosis &#40;SEA for its initials in Spanish&#41; standards indicate how to reverse this situation&#58; to be truly efficient more intense and early prevention of the disease risk factors must be achieved&#46; Not an easy task and one that carries responsibilities at different levels&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Society as a whole is responsible&#44; especially the health authorities that must guide their policies on internationally accepted scientific evidence such as that reflected in the SEA document&#46; There is too much controversy&#44; artificially created for the most part&#44; regarding the benefit of controlling risk factors that minimise risk and questioning interventions that are summarised in the document with highly solid scientific information&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Healthcare professionals also play a vital role in the control of cardiovascular risk factors&#46; Our first responsibility is to be well trained so that the public may be offered the best&#44; appropriate&#44; evidence-based treatment&#46; Due to the enormity of scientific information surrounding cardiovascular disease&#44; it is impossible to know what is important&#44; to discern between the wheat and the chaff&#44; and for this the recommendations of scientific societies are essential&#46; The SEA standards compile that information&#46; All risk factors&#44; their importance&#44; their best diagnostic procedure and the best available treatments are reviewed in detail&#46; It is a document that has been able to effectively summarise the best of the main international recommendations and is therefore a must-read and permanent reference document for healthcare professionals involved in cardiovascular prevention&#46; Continuous advance in knowledge entails that a document of these characteristics must be updated periodically&#46; We believe updating the standards to be essential&#44; and is also SEA&#8217;s intention&#44; with reporting on what has remained and what has changed with respect to previous editions&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Although training and information for health professionals is a priority objective for the SEA&#44; its main objective is to contribute from scientific knowledge to the prevention and treatment of arteriosclerosis diseases and this is impossible without society&#8217;s participation&#46; Cardiovascular prevention as an individual obligation must be promoted and even required by the health system&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> There must be acknowledgement of the fact not enough emphasis has been placed on this fundamental aspect&#46; The perception exists that cardiovascular disease is an inevitable problem in advanced stages of life and is somewhat random in its nature&#46; We must convey that cardiovascular health is not the result of chance&#44; that it can be avoided&#44; and that when it is allowed to evolve&#44; solutions become difficult and expensive&#46; To do this the public has to be well informed and this is not easy&#46; The enormous quantity of information&#44; that is sometimes discordant and of self-interest&#44; makes training doctors difficult&#44; and ever more so the general population&#46; We would encourage the SEA to also lead this process by periodically publishing the &#8220;standards for cardiovascular prevention for citizens&#46;&#8221; All the information collected in the latest document must be rigorously explained and lifestyle guidelines given&#44; together with the expected benefit of each intervention&#44; what should be controlled&#44; how to do this and how often&#46; The public need to be assured that the information collected is the best at all times&#44; differentiating evidence from opinion&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Our congratulations to the SEA&#44; and particularly to the authors of the document for their great efforts&#46; This documented is an essential reference tool&#44; aiding our responsibility to practice the best possible medicine&#46;</p></span>"
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                    0 => array:2 [
                      "titulo" => "Low-density lipoproteins cause atherosclerotic cardiovascular disease&#46; 1&#46; Evidence from genetic&#44; epidemiologic&#44; and clinical studies&#46; A consensus statement from the European Atherosclerosis Society Consensus Panel"
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                        "numero" => "32"
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                    0 => array:2 [
                      "titulo" => "Estimating lifetime healthcare costs with morbidity data"
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                            3 => "I&#46; S&#225;nchez"
                            4 => "J&#46;M&#46; Inoriza"
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                      "titulo" => "Self-responsibility for our good health"
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Original language: English
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es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

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