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Inicio Clínica e Investigación en Ginecología y Obstetricia Bacterial vaginosis and Mycoplasma infections in reproductive-age women: Clarify...
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Vol. 49. Issue 4.
(October - December 2022)
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Vol. 49. Issue 4.
(October - December 2022)
Original article
Bacterial vaginosis and Mycoplasma infections in reproductive-age women: Clarifying the association with risk factors
Vaginosis bacteriana e infecciones por micoplasma en mujeres en edad reproductiva: aclarando la asociación con factores de riesgo
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S. Eroglua,
Corresponding author
drsemraeroglu@gmail.com

Corresponding author.
, N. Asginb
a Semra Eroglu, Samsun University, Department of Gynecology and Obstetrics, Samsun, Turkey
b Nergis Asgin, Karabuk University Faculty of Medicine, Department of Microbiology, Turkey
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Abstract
Objectives

This study seeks to examine the association between predisposing risk factors and the prevalence of bacterial vaginosis (BV) as well as Mycoplasma hominis (MH) and Ureaplasma urealyticum (UU) infections in reproductive age women and investigate its relationship with infertility.

Methods

This cross-sectional, prospective study was carried out using sexually active females who presented at the Gynaecology Clinic with complaints of vaginal discharge. Two cervical smear samples were taken from the endocervical canal using sterile cotton swabs for each patient. The patients were questioned to obtain their demographic data and potential risk factors for lower genital tract infections, and their responses were recorded.

Results

Of 348 patients, BV was detected in 46.3%, UU in 26.7%, MH in 3.7% and UU and MH co-infection in 13.2%. The prevalence of BV concomitant with UU and/or MH was significantly high (p=.001). The most prominent risk factors for BV were UU and MH infection (AOR=6.79, 95% confidence interval (CI): [2.63–17.56]), vaginal douche use (AOR=6.80, 95% CI: [03.60–12.83]), abortion history (AOR=2.82, 95% CI: [1.55–5.12]) and high body mass indexes (BMI) (AOR=.81, 95% CI: [.74–.89]). The prevalence of BV, UU and MH was significantly higher in infertile patients than fertile patients (p=.002).

Conclusions

Bacterial vaginosis, MH, and UU co-infection were common in patients with vaginal discharge, and it was detected considerably higher in infertile patients than in fertile patients.

Keywords:
Bacterial vaginosis
Infertility
Mycoplasma hominis
Prevalence
Ureaplasma urealyticum
Resumen
Objetivos

Este estudio busca examinar la asociación entre los factores de riesgo predisponentes y la prevalencia de la vaginosis bacteriana (VB), así como las infecciones por Mycoplasma hominis (MH) y Ureaplasma urealyticum (UU) en mujeres en edad reproductiva e investigar su relación con la infertilidad.

Métodos

Estudio transversal y prospectivo que se llevó a cabo con mujeres sexualmente activas que acudieron a la Clínica de Ginecología con quejas de flujo vaginal. Con hisopos de algodón estériles, se tomaron dos muestras de frotis cervical del canal endocervical. Se interrogó a las pacientes para obtener sus datos demográficos y se registraron los posibles factores de riesgo de infecciones del tracto genital inferior y sus respuestas.

Resultados

Entre 348 pacientes, se detectó VB en el 46,3%, UU en el 26,7%, HM en el 3,7% y coinfección por UU y HM en el 13,2%. La prevalencia de VB concomitante con UU y/o MH fue significativamente alta (P=0,001). Los factores de riesgo más destacados para la VB fueron la infección por UU y MH (AOR=6,79, intervalo de confianza (IC) del 95%: [2,63-17,56]), uso de duchas vaginales (AOR=6,80, IC del 95%: [03,60-12,83]), antecedentes de aborto (AOR=2,82, IC del 95%: [1,55–5,12]) e índices de masa corporal (IMC) altos (AOR=0,81, IC del 95%: [0,74-0,89]). La prevalencia de BV, UU y MH fue significativamente mayor en pacientes infértiles que en pacientes fértiles (P=0,002).

Conclusiones

Se encontró que la coinfección por BV, MH y UU era común en pacientes con flujo vaginal, y también este aumento fue significativamente mayor en pacientes infértiles que en pacientes fértiles.

Palabras clave:
Vaginosis bacteriana
Infertilidad
Mycoplasma hominis
Prevalencia
Ureaplasma urealyticum

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