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Inicio Clínica e Investigación en Ginecología y Obstetricia Fertility preservation in endometriosis: Review of current evidence and best pra...
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Vol. 51. Issue 2.
(April - June 2024)
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Vol. 51. Issue 2.
(April - June 2024)
Review article
Fertility preservation in endometriosis: Review of current evidence and best practices
Preservación de la fertilidad en la endometriosis: revisión de la evidencia actual
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315
M. Carbonell
Corresponding author
, M.A. Perelló, J. Herrero
Hospital Universitario Vall d’Hebron, Barcelona, Spain
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Table 1. Characteristics of included studies.
Table 2. Available recommendations on fertility preservation for endometriosis.
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Special issue
This article is part of special issue:
Preservación de la fertilidad / Fertility Preservation

Edited by: Dolors Manau - Assisted Human Reproduction Unit Institute of Gynecology, Spain
César Díaz García - IVIRMA London, UK

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Abstract

In recent decades, the field of female fertility preservation has experienced substantial growth. Reliable techniques such as cryopreservation of oocytes and ovarian tissue have emerged, along with more established methods such as embryo freezing. Among the group of patients who can benefit from these new techniques are patients with endometriosis, a common disease capable of compromising ovarian reserve and fertility prospects. Unfortunately, comprehensive recommendations for fertility preservation in patients with endometriosis are still lacking.

This narrative review comprehensively explores fertility preservation in patients with endometriosis, using a range of relevant literature, including available national and international guidelines. Additionally, it explains the weight of several factors that contribute to the decision-making process for fertility preservation, including age, severity of endometriosis, ovarian reserve, and previous or future surgery.

This manuscript summarizes available recommendations that provide guidance for this vital but challenging aspect of reproductive medicine. Underlines the need for personalized care for patients with an early diagnosis of endometriosis and initial medical treatment to try to reduce the deterioration of ovarian reserve and emphasizes the importance of research to refine fertility preservation strategies in people with endometriosis.

Keywords:
Endometriosis
Fertility preservation
Cryopreservation
Endometrioma
Resumen

En las últimas décadas, el campo de la preservación de la fertilidad femenina ha experimentado un crecimiento sustancial. Han surgido técnicas fiables, como la criopreservación de ovocitos y tejido ovárico, junto con algunas más establecidas como la congelación de embriones. Entre el grupo de pacientes que se pueden beneficiar de estos nuevos métodos, están aquellas con endometriosis, una enfermedad frecuente y capaz de comprometer la reserva ovárica y las perspectivas de fertilidad. Desafortunadamente, todavía faltan recomendaciones integrales para la preservación de esta en pacientes con endometriosis.

Esta revisión narrativa explora exhaustivamente la conservación de la fertilidad en pacientes con endometriosis, utilizando una variedad de literatura pertinente, incluidas las pautas nacionales e internacionales disponibles. Además, explica el peso de varios factores que contribuyen al proceso de toma de decisiones para conservar la fertilidad, incluida la edad, la gravedad de la endometriosis, la reserva ovárica y la cirugía previa o futura.

Este manuscrito, resume las recomendaciones disponibles que brindan orientación para este aspecto vital pero desafiante de la medicina reproductiva. Subraya la necesidad de una atención personalizada a la paciente con un diagnóstico de endometriosis precoz y un tratamiento inicial médico para intentar disminuir el deterioro de la reserva ovárica y enfatiza la importancia de la investigación para refinar las estrategias de preservación de la fertilidad en las personas que presentan endometriosis.

Palabras clave:
Endometriosis
Preservación de la fertilidad
Criopreservación
Endometrioma

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