Laparotomía de second looken el tratamiento del áncer epitelial de ovario | Clínica e Investigación en Ginecología y Obstetricia

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Resumen

Objetivo:Realizar un estudio retrospectivo en las pacientes con cáncer epitelial de ovario (CEO) diagnosticadas en nuestra área de salud (Cabueñes,Gijón) entre 1991 y 2001.

Material y métodos:Revisamos las características de las pacientes, del tumor y del tratamiento realizado, con el fin de establecer el papel de la laparatomía de second look (LSL) en el tratamiento del CEO y su posible impacto en la supervivencia de las pacientes.

Resultados:Durante el período de estudio,se realizó LSL a 70 pacientes que,tras completar el tratamiento primario con cirugía y quimioterapia,se encontraban aparentemente libres de enfermedad. Aunque las mujeres con LSL negativa tuvieron mejor supervivencia que las pacientes con enfermedad residual, no se encontraron diferencias estadísticamente significativas en la supervivencia global y la supervivencia post-LSL en función del tumor residual después de esta cirugía. Al finalizar el tratamiento,encontramos un 41% de recurrencias entre las pacientes que se encontraban libres de enfermedad,cifra muy similar al 39% hallado entre las pacientes con LSL negativa,lo que demuestra el alto índice de falsos negativos de esta cirugía.

Abstract

Objective:To carry out a retrospective study on patients with ovarian epithelial cancer (OEC), diagnose in our Health Area (Cabuenes, Gijón) from 1991 to 2001.

Material and methods:We review the patient’s characteristics, tumor and treatment carried out, with the intention of establishing the role of second look laparotomy (SLL) in the treatment of OEC, and its possible impact on patients survival.

Results:During the period studied SLL was carried out on 70 patients who, following primary treatment with surgery and chemotherapy were apparently free f disease. Although the women with negative SLL had better survival rates than women with residual disease, no statistically significant differences in global survival or post-SLL were found, even when there was residual disease following this surgery. On completion of treatment, we found recurrence in 41% of patients had been disease free, a level very similar to the 39% found in the patients with negative SLL, which demonstrates the high index of false negatives in this type of surgery.

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