Assessing the completeness of reporting of observational studies in Colombian Journal of Anesthesiology. Cross sectional study

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Cross sectional study" ] ] "contieneResumen" => array:2 [ "es" => true "en" => true ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0015" "etiqueta" => "Figura 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 981 "Ancho" => 3019 "Tamanyo" => 231557 ] ] "descripcion" => array:1 [ "es" => "Tendencia en la completitud global anual de los estudios observacionales publicados en la RCA entre 2000 y 2013 (n=23). Las ecuaciones de la recta en la parte superior representan la proporción de incremento en completitud por año durante los 2 periodos. En el primer periodo este incremento (coeficiente B) fue del 0,8%, y en el segundo periodo, del 0,4%. 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Cross sectional study" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "31" "paginaFinal" => "38" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Mary Bravo-Peña, Luis Barona-Fong, Julio Campo-López, Yeni Arroyave, José Andrés Calvache" "autores" => array:5 [ 0 => array:3 [ "nombre" => "Mary" "apellidos" => "Bravo-Peña" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "Luis" "apellidos" => "Barona-Fong" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] ] ] 2 => array:3 [ "nombre" => "Julio" "apellidos" => "Campo-López" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] ] ] 3 => array:3 [ "nombre" => "Yeni" "apellidos" => "Arroyave" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "b" "identificador" => "aff0010" ] ] ] 4 => array:4 [ "nombre" => "José Andrés" "apellidos" => "Calvache" "email" => array:1 [ 0 => "jacalvache@gmail.com" ] "referencia" => array:3 [ 0 => array:2 [ "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "c" "identificador" => "aff0020" ] 2 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Department of Anesthesiology, Universidad del Cauca, Popayán, Colombia" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Department of Surgery, Universidad del Cauca, Popayán, Colombia" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Department of Anesthesiology, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands" "etiqueta" => "c" "identificador" => "aff0020" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author at: Departamento de Anestesiología, Hospital Universitario San José, Cra 6N.° 10N-142, tercer piso, Popayán, Colombia." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "¿Es completo el reporte de los estudios observacionales publicados en la Revista Colombiana de Anestesiología? estudio de corte transversal" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:9 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "fuente" => "Source: Authors." "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 955 "Ancho" => 1361 "Tamanyo" => 86981 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at3" "detalle" => "Table " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "Selection of the studies included (n=23)." ] ] ] "textoCompleto" => "IntroductionObservational scientific research describes and analyses reality without intervening,<a class="elsevierStyleCrossRef" href="#bib0235">1</a> and does not establish definitive causal relationships, but it provides scientific bases regarding the health/disease process and guides future research.Bearing in mind that in various settings there are implications that preclude intervention (such as studies on the safety of pharmacological or non-pharmacological interventions), observational studies account for the majority of publications in the area of health.<a class="elsevierStyleCrossRef" href="#bib0240">2</a> These are lower-cost studies, easier to design and perform, and useful for healthcare planning and administration.<a class="elsevierStyleCrossRef" href="#bib0245">3</a>The STROBE statement (Strengthening the Reporting of Observational Studies in Epidemiology) was designed in 2004 in Bristol, United Kingdom, and published in 2007<a class="elsevierStyleCrossRef" href="#bib0250">4</a> with the aim of improving observational research reporting. A framework comprising 22 items was developed with the goal of making observational results truly useful by means of an appropriate reporting of cohort, case–control and cross-sectional studies.<a class="elsevierStyleCrossRef" href="#bib0250">4</a> The three research designs share 18 of the 22 items in the Statement, whereas the other 4 are specific for each. The items include the Title, Abstract, Introduction, Methodology, Results and Discussion sections.<a class="elsevierStyleCrossRef" href="#bib0250">4</a> The STROBE statement is not a model for conducting an observational study and it does not assess the quality of a study directly. Rather, it is more a completeness guideline for authors or readers, and has been used to assess this characteristic in various medical disciplines.<a class="elsevierStyleCrossRefs" href="#bib0255">5–12</a>The Colombian Journal of Anaesthesiology (RCA) was published for the first time in September 1973; the first few articles were narrative reviews related to the practice of anaesthesiology but the journal later became a medium for disseminating original research results. At present, it is the official communication medium of the Colombian Society of Anaesthesiology and the main medium for the dissemination of research in anaesthesiology and related areas in Colombia. In 1999, the Cochrane Collaboration found that RCA is the Colombian journal that publishes the largest number of reports on intervention studies, systematic reviews and meta-analyses.<a class="elsevierStyleCrossRef" href="#bib0295">13</a>Recently, RCA adopted the guidelines of the EQUATOR network (Enhancing the QUAlity and Transparency Of health Research), which includes the STROBE statement for its editorial process as well as a firm suggestion about its use for its authors.<a class="elsevierStyleCrossRef" href="#bib0300">14</a>The main objective of this study was to determine the completeness of reporting of observational studies published in RCA between 2000 and 2013, using the STROBE statement. Additionally, to analyse the completeness of observational study reporting before and after the publication of the STROBE statement, quantify the trend, and establish recommendations regarding complete reporting of observational research in anaesthesiology in Colombia.MethodologyCross-sectional observational study. The subjects for the analysis were all the observational studies published in RCA between 2000 (volume 28) and 2013 (volume 41). The RCA archive hosted in the website and the database of the tables of content and abstracts in Science Direct were initially explored.Studies classified as “observational” were those defined as such by their authors: cohort studies, case–control studies and cross-sectional (or prevalence) studies, and they were initially classified based on the evaluation of each abstract. Studies that were excluded were those without a clear, well-defined methodological design, editorials, letters to the editor, reflection articles, narrative or systematic reviews of the literature, case reports and case series.A total of 55 observational studies were identified. Because of the exploratory nature of the study, a random selection of 40% (22 studies) was made, and annual representation in the sample to analyse was ensured by means of proportional fixation by year. Based on reports on prior publications, the sample size was estimated using a completeness proportion of 60%, 15% accuracy and 95% CI, for n=24.An assessment tool developed on the basis of the STROBE statement and aimed at evaluating the reporting completeness for each study was applied. This tool and minor modifications thereof have ween widely used in the literature for similar purposes.<a class="elsevierStyleCrossRefs" href="#bib0250">4–12</a>The selected studies were divided into 2 groups and two researchers already familiar with the research methodology, the health research designs and the STROBE initiative were assigned to each group (Group 1: JC-YA, Group 2: MB-LB). Each researcher, working separately, applied the list of items to each study in order to determine whether they were “met”, “unmet” or did “not apply”, in accordance with the specific type of design. Regular follow-up meetings were held, during which the researchers shared their results, reviewed and discussed the cases for which the assessment was inconclusive. In cases of difficulty, the rating was discussed individually with a research advisor (JAC).The dependent variable (primary outcome) was completeness of the report of each study assessed. Additionally, other variables were explored, such as sample size, number of authors, number of professors, presence or not of individuals with Masters or PhD degrees in the research team, and the year of publication.Statistical analysisAll statistical analyses were made using the SPSS 21.0 and R software package.<a class="elsevierStyleCrossRef" href="#bib0305">15</a> Completeness rating for each study was the sum of all the items in the assessment. Considering that the total number of variables assessed was different for each research design (cohort, case–controls, and cross-sectional) the individual final result was weighted, and the median rating between the two reviewers and the range as a measure of scatter were estimated. The degree of agreement regarding completeness rating was analysed using the intra-class correlation coefficient (ICC). This agreement was assessed for study segments and also globally.The general description of the results was made using descriptive techniques in accordance with the nature of each variable. Non-parametric tests were used for univariate contrasting (Mann–Whitney U Test) using report completeness as the dependent variable.A time series analysis was made using an autoregressive integrated moving average (ARIMA) model that allows to assess trends before and after an intervention. This methodology considers multiple evaluation points before and after an intervention and the existing autocorrelation between those points.<a class="elsevierStyleCrossRefs" href="#bib0310">16,17</a> Pre-intervention (2007: year of the STROBE initiative publication) and post-intervention periods were used. Their results are presented as the difference in the slope of the regression line before and after the intervention. Additionally, the effect of the intervention for 2009, 2012 and 2013 is also presented. Statistical significance was predefined as a p value of 0.05.Finally, a multiple linear regression model was developed in which the degree of completeness was considered as the outcome, and the year of publication, sample size, the number of authors, the number of professors and the presence or absence of individuals with masters degrees or PhDs in the research team were considered as independent variables. The results are presented as the regression coefficient and their corresponding p values. The adjustment of this model was valued using the graphic residual analysis.ResultsOverall, 22 observational studies published in RCA between 2000 and 2013 were analysed.<a class="elsevierStyleCrossRefs" href="#bib0320">18–39</a> One of them was reported as a two-phase study, so it was divided separately for a total of 23 (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> shows the general characteristics of the studies included. The median overall completeness of the items in the STROBE statement was 57%, 95%CI (48–66%). The sections for which greater completeness was documented were the Title and the Introduction (89% each). Completeness for each section of the research articles is shown in <a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>.<elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a> shows completeness results by reviewer and article sections, and the degree of agreement between reviewer pairs by group.<elsevierMultimedia ident="tbl0010"></elsevierMultimedia>The overall completeness trend is shown in graph form (<a class="elsevierStyleCrossRef" href="#fig0015">Fig. 3</a>) for before and after the publication of the STROBE strategy. The linear equation for completeness is shown for each of the sections as a function of the year of publication. Greater rating variability was found for the post-STROBE period. The slope of the straight line for the time period before the intervention was 0.85. The difference in the slope of the line between the before and after time periods was −0.47 (p=0.709). Change coefficients in the slope of the line for 2009, 2021 and 2013 were, respectively, −3.2 (p=0.698), −5.1 (p=0.628) and −7.5 (p=0.626).<elsevierMultimedia ident="fig0015"></elsevierMultimedia>The completeness of the reports that included the presence of an author with a Master's or PhD degree was higher (p=0.03). The adjusted effect of the study variables on completeness is shown in <a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>.<elsevierMultimedia ident="tbl0015"></elsevierMultimedia>DiscussionThe main findings of this study are, first, that completeness of observational studies published in RCA is 57%, and the Title and Introduction are the sections with the greatest completeness, while Methodology and Results are the ones with the greatest deficiencies. Second, during the 13-year study period there is a very slow increase in completeness, and there is no evidence that the publication of the STROBE statement in 2007 had any effect on completeness for RCA.The completeness of observational studies is similar to that reported by other authors. Several research studies have documented completeness ranges of 30–85%.<a class="elsevierStyleCrossRefs" href="#bib0255">5,6,9,10,12,40</a> In 2011, Poorolajal et al., analysed observational studies in the New England Journal of Medicine, Journal of the American Medical Association, Lancet, British Medical Journal, Archives of Internal Medicine, and the Canadian Medical Association Journal, and found an overall compliance of 69% (95% CI 59–79%).<a class="elsevierStyleCrossRef" href="#bib0280">10</a> In 2013, Bastuji-Garin et al., published a similar study in which they analysed observational studies of four European dermatology journals. The mean rating using the STROBE tool was 57% (range 18–98%).<a class="elsevierStyleCrossRef" href="#bib0275">9</a> Percentages vary in specific areas of knowledge, from satisfactory quality of reporting, like in the study by Papathanasiou et al. in oncology which included publications between 2008 and 2009, where completeness reported ranged between 70 and 90%,<a class="elsevierStyleCrossRef" href="#bib0265">7</a> all the way to low proportions, such as those reported by Sorensen et al., where compliance in observational studies on hand surgery published between 2005 and 2011 was 38%, with a range between 10 and 54%.<a class="elsevierStyleCrossRef" href="#bib0260">6</a> This might be influenced by the range of time during which the studies were developed in relation to the time of publication of the statement, and the awareness of scientists and authors regarding the importance of completeness when it comes to disseminating information. Despite having analysed 40% of the studies, the accuracy of our completeness estimation had a 95% CI of 48–66%, leaving an impression of the need for future improvement.Authors like Fung and Langan et al., found that the items with the highest percentage of compliance were the Title, the Introduction and the Abstract. Of the publications analysed by Fung, 100% met the criteria established by STROBE for the Introduction, 86% and 93% for the Title and the Abstract, respectively. Compliance found by Langan et al. was 97% for the Introduction, 87% for the Title and 93% for the Abstract.<a class="elsevierStyleCrossRefs" href="#bib0270">8,41</a> Consistent with the literature mentioned above, for RCA publications we found an 89% compliance with the STROBE guidelines for the Title and the Abstract.The sections with the lowest completeness ratings were Methodology and Results, and this is consistent with results from similar studies. Galera et al., found that none of the articles reviewed were in compliance with the items recommended for Methods and Results.<a class="elsevierStyleCrossRef" href="#bib0290">12</a> In the work by Fung, reporting completeness for the section on Materials and Methods varied, with item ratings ranging between 7% and 97%.<a class="elsevierStyleCrossRef" href="#bib0270">8</a> Low completeness for these sections may be related with their degree of complexity. For example, the methodology section requires detailed knowledge of epidemiology and biostatistics, which is not always widely available or accessible. It is worth noting that the section on Methods and Results had the lowest scores for domain agreement between reviewers (ICC of less than a 0.5). This fact reinforces the hypothesis that these are sections of a manuscript that require prior training and sound knowledge of research methodology both for writing as well as for analytical purposes.During the 13 years selected for this assessment, there was evidence of a slight trend towards improved report completeness. This trend is quite slow (0.4 a 0.8% per year). In their study, Bastuji-Garin et al. show an increase during the study period (2004–2010) of close to 2% per year.<a class="elsevierStyleCrossRef" href="#bib0275">9</a> The results of this analysis must be taken cautiously because of the great variability found during the post-STROBE period in the overall rating for certain studies. Additional studies regarding RCA have found that, over time, the risk of bias of the reported studies has diminished.<a class="elsevierStyleCrossRef" href="#bib0440">42</a>No evidence was found in this study in the sense that the publication of STROBE had any significant impact on the completeness of the observational research published in RCA. This fact has been replicated by other authors.<a class="elsevierStyleCrossRef" href="#bib0270">8</a> Despite the publication of the strategy in 2007 and of its wide dissemination in the scientific media, many publications and journals were late in adopting it. RCA adopted the guidelines of the EQUATOR network, including STROBE, in 2013.<a class="elsevierStyleCrossRef" href="#bib0300">14</a> With the use of other statements like CONSORT there has been a consistent increase in the completeness of published reports.<a class="elsevierStyleCrossRef" href="#bib0445">43</a> Fortunately, the scientific community in general is increasingly attaching greater importance to research completeness as a strategy to improve reproducibility and increase its validity.<a class="elsevierStyleCrossRefs" href="#bib0450">44–46</a>The effect of some variables on the completeness of study reports was almost negligible. Only the presence of researchers with Masters and/or PhD degrees increased report completeness significantly (by approximately 10%). Although this is not a statistically significant increase and requires a critical analysis, it is plausible. Moreover, the size of the study sample may have lowered the power of the study for detecting actual differences (type II error).As far as we know, this is the first study to analyse the completeness of observational research reports in anaesthesiology and other areas in Colombia. Noteworthy among the strengths of the study are the thorough search of observational studies in RCA, the analysis of completeness performed by 4 independent reviewers, and the participation of an arbitrator to solve discrepancies. This resulted in a lower possibility of selection and information bias. The main limitation was failure to study the entire population of observational studies, which undermined the confidence of our overall completeness estimate. However, our objective was to document its existence in order to promote improvement. Below are the main recommendations of this study.Ethical disclosuresProtection of human and animal subjectsThe authors declare that no experiments were performed on humans or animals for this study.Confidentiality of dataThe authors declare that no patient data appear in this article.Right to privacy and informed consentThe authors declare that no patient data appear in this article.FundingNone.Conflicts of interestNone declared." "textoCompletoSecciones" => array:1 [ "secciones" => array:12 [ 0 => array:3 [ "identificador" => "xres785805" "titulo" => "Abstract" "secciones" => array:5 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Introduction" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Objective" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Methods" ] 3 => array:2 [ "identificador" => "abst0020" "titulo" => "Results" ] 4 => array:2 [ "identificador" => "abst0025" "titulo" => "Conclusion" ] ] ] 1 => array:2 [ "identificador" => "xpalclavsec784517" "titulo" => "Keywords" ] 2 => array:3 [ "identificador" => "xres785806" "titulo" => "Resumen" "secciones" => array:5 [ 0 => array:2 [ "identificador" => "abst0030" "titulo" => "Introducción" ] 1 => array:2 [ "identificador" => "abst0035" "titulo" => "Objetivo" ] 2 => array:2 [ "identificador" => "abst0040" "titulo" => "Métodos" ] 3 => array:2 [ "identificador" => "abst0045" "titulo" => "Resultados" ] 4 => array:2 [ "identificador" => "abst0050" "titulo" => "Conclusión" ] ] ] 3 => array:2 [ "identificador" => "xpalclavsec784516" "titulo" => "Palabras clave" ] 4 => array:2 [ "identificador" => "sec0005" "titulo" => "Introduction" ] 5 => array:3 [ "identificador" => "sec0010" "titulo" => "Methodology" "secciones" => array:1 [ 0 => array:2 [ "identificador" => "sec0015" "titulo" => "Statistical analysis" ] ] ] 6 => array:2 [ "identificador" => "sec0020" "titulo" => "Results" ] 7 => array:2 [ "identificador" => "sec0025" "titulo" => "Discussion" ] 8 => array:3 [ "identificador" => "sec0030" "titulo" => "Ethical disclosures" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0035" "titulo" => "Protection of human and animal subjects" ] 1 => array:2 [ "identificador" => "sec0040" "titulo" => "Confidentiality of data" ] 2 => array:2 [ "identificador" => "sec0045" "titulo" => "Right to privacy and informed consent" ] ] ] 9 => array:2 [ "identificador" => "sec0050" "titulo" => "Funding" ] 10 => array:2 [ "identificador" => "sec0055" "titulo" => "Conflicts of interest" ] 11 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2016-05-04" "fechaAceptado" => "2016-09-05" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec784517" "palabras" => array:5 [ 0 => "Observational study" 1 => "Anesthesiology" 2 => "Epidemiologic studies" 3 => "Medical education" 4 => "Statistical analysis" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec784516" "palabras" => array:5 [ 0 => "Estudio observacional" 1 => "Anestesiología" 2 => "Estudios epidemiológicos" 3 => "Educación médica" 4 => "Análisis estadístico" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:3 [ "titulo" => "Abstract" "resumen" => "IntroductionThe STROBE statement (Strengthening the Reporting of Observational Studies in Epidemiology), consisting of 22 points, was published in 2007 with the aim of improving the reporting of observational research. ObjectiveTo determine the completeness of reporting of observational studies published in the Colombian Journal of Anaesthesiology between 2000 and 2013 using STROBE. MethodsCross-sectional study. The units of analysis were observational studies published in Colombian Journal of Anesthesiology between 2000 (volume 28) and 2013 (volume 41). Of the randomly selected studies, 40% were included. The primary outcome was the completeness of the report of each study. Using two groups, the researchers applied the STROBE statement independently, supported by an arbitrator. Descriptive analyses, time series analyses and multiple linear regression analyses were used. ResultsOverall, 55 studies were identified and 22 (40%) were randomly chosen. The median overall completeness according to STROBE was 57%, 95% CI (48–66%). Items with higher completeness in the reports were the Title and Introduction (89% each), followed by Methods 53%, Results 50%, and Discussion 58%. There were no significant differences between before and after the publication of STROBE. ConclusionThe completeness of reporting of observational studies in the Colombian Journal of Anaesthesiology is close to 60%, according to results worldwide. No change was found as a result of the publication of the STROBE Statement in 2007." "secciones" => array:5 [ 0 => array:2 [ "identificador" => "abst0005" "titulo" => "Introduction" ] 1 => array:2 [ "identificador" => "abst0010" "titulo" => "Objective" ] 2 => array:2 [ "identificador" => "abst0015" "titulo" => "Methods" ] 3 => array:2 [ "identificador" => "abst0020" "titulo" => "Results" ] 4 => array:2 [ "identificador" => "abst0025" "titulo" => "Conclusion" ] ] ] "es" => array:3 [ "titulo" => "Resumen" "resumen" => "IntroducciónLa declaración STROBE (Strenghtening the Reporting of Observational Studies in Epidemiology) se publicó en el 2007 con el objetivo de mejorar el reporte de la investigación de tipo observacional, consta de 22 puntos. ObjetivoDeterminar la completitud del reporte de estudios observacionales publicados en la Revista Colombiana de Anestesiología entre el año 2000 al 2013 mediante STROBE. MétodosEstudio observacional de corte transversal. La unidad de análisis fueron los estudios observacionales publicados en la Revista Colombiana de Anestesiología desde el año 2000 (volumen 28) hasta el año 2013 (volumen 41). Se incluyó un 40% del total de estudios seleccionados aleatoriamente. El desenlace primario fue la completitud del reporte de cada estudio. Mediante dos grupos, los investigadores aplicaron la declaración STROBE de forma independiente con el apoyo de un árbitro. Se utilizó análisis descriptivo, análisis de series temporales y regresión lineal múltiple. ResultadosSe identificaron 55 estudios y se escogieron al azar 22 (40%). La mediana de completitud global de STROBE fue de 57% IC95% (48%-66%). Los ítems con mayor completitud de los reportes fueron en el título y la introducción (89% cada uno), métodos: 53%, Resultados 50%, discusión 58%. No se encontró diferencias significativas entre el periodo pre y post publicación de STROBE. ConclusiónLa completitud del reporte de los estudio observacionales de la Revista Colombiana de Anestesiología es cercana al 60%, acorde con resultados a nivel mundial. No presentó cambios con la publicación de la declaración STROBE en el 2007." "secciones" => array:5 [ 0 => array:2 [ "identificador" => "abst0030" "titulo" => "Introducción" ] 1 => array:2 [ "identificador" => "abst0035" "titulo" => "Objetivo" ] 2 => array:2 [ "identificador" => "abst0040" "titulo" => "Métodos" ] 3 => array:2 [ "identificador" => "abst0045" "titulo" => "Resultados" ] 4 => array:2 [ "identificador" => "abst0050" "titulo" => "Conclusión" ] ] ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "Please cite this article as: Bravo-Peña M, Barona-Fong L, Campo-López J, Arroyave Y, Calvache JA. ¿Es completo el reporte de los estudios observacionales publicados en la Revista Colombiana de Anestesiología? Estudio de corte transversal. Rev Colomb Anestesiol. 2017;45:31–38." ] ] "multimedia" => array:6 [ 0 => array:9 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "fuente" => "Source: Authors." "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 955 "Ancho" => 1361 "Tamanyo" => 86981 ] ] "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at3" "detalle" => "Table " "rol" => "short" ] ] "descripcion" => array:1 [ "en" => "Selection of the studies included (n=23)." ] ] 1 => array:8 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "fuente" => "Source: Authors." "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 864 "Ancho" => 1601 "Tamanyo" => 72255 ] ] "descripcion" => array:1 [ "en" => "Completeness for research article sections (n=23)." ] ] 2 => array:8 [ "identificador" => "fig0015" "etiqueta" => "Fig. 3" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "fuente" => "Source: Authors." "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr3.jpeg" "Alto" => 981 "Ancho" => 3019 "Tamanyo" => 228259 ] ] "descripcion" => array:1 [ "en" => "Overall annual completeness trend of the observational studies published in RCA between 2000 and 2013 (n=23). Note: The straight line equations in the upper part represent the proportion of increased completeness by year during the two periods. During the first period, the increase (B coefficient) was 0.8%, and during the second period, the increase was 0.4%." ] ] 3 => array:8 [ "identificador" => "tbl0005" "etiqueta" => "Table 1" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at1" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "leyenda" => "Source: Authors." "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="" valign="top" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Frequency (%) Mean μ±1SD Median [IQR] \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry " colspan="2" align="left" valign="top">Year of publication</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">2000–2003 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">7 (30) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">2004–2007 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">5 (22) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">2008–2011 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">5 (22) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">2012–2013 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">6 (26) \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="2" align="left" valign="top"></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Total number of authors \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">μ=3.7±2 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="" valign="top"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Median=3 [3–5] \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="2" align="left" valign="top"></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Number of faculty \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">μ=1.7±1 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " align="" valign="top"> \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Median=1 [1–3] \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="2" align="left" valign="top"></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Study sample size \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">Median=212 [65–260] \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="2" align="left" valign="top"></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Presence of author with masters degree or PhD \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="left" valign="top">18 (78) \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1306369.png" ] ] ] ] "descripcion" => array:1 [ "en" => "General characteristics of the studies included (n=23)." ] ] 4 => array:8 [ "identificador" => "tbl0010" "etiqueta" => "Table 2" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "detalles" => array:1 [ 0 => array:3 [ "identificador" => "at2" "detalle" => "Table " "rol" => "short" ] ] "tabla" => array:2 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="" valign="top" scope="col"> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Group 1 (n=12)</th><th class="td" title="table-head " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Group 2 (n=11)</th></tr><tr title="table-row"><th class="td" title="table-head " align="" valign="top" scope="col" style="border-bottom: 2px solid black"> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Reviewer 1 \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Reviewer 2 \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Agreement<a class="elsevierStyleCrossRef" href="#tblfn0005">*</a> \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Reviewer 1 \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Reviewer 2 \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Agreement<a class="elsevierStyleCrossRef" href="#tblfn0005">*</a> \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Title \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">95.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">95.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1.00 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">77.3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">81.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.86 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Introduction \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">87.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">95.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.64 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">86.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">90.9 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.77 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Methods \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">64.5 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">52.0 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.53 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">54.7 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">46.4 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.56 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Results \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">70.6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">33.6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.28 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">54 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">45.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.56 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Discussion \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">73.3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">56.6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.53 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">42.3 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">59.6 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.45 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry " colspan="7" align="left" valign="top"></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Total \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">70.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">52.8 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.49 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">55.9 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">52.2 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.59 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1306371.png" ] ] ] "notaPie" => array:1 [ 0 => array:3 [ "identificador" => "tblfn0005" "etiqueta" => "*" "nota" => "Intraclass correlation coefficient. Source: Authors." ] ] ] "descripcion" => array:1 [ "en" => "Completeness rated by each reviewer by article sections and degree of agreement between reviewer pairs by group (n=23)." ] ] 5 => array:8 [ "identificador" => "tbl0015" "etiqueta" => "Table 3" "tipo" => "MULTIMEDIATABLA" "mostrarFloat" => true "mostrarDisplay" => false "fuente" => "Source: Authors." "tabla" => array:1 [ "tablatextoimagen" => array:1 [ 0 => array:2 [ "tabla" => array:1 [ 0 => """ <table border="0" frame="\n \t\t\t\t\tvoid\n \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head " align="left" valign="top" scope="col" style="border-bottom: 2px solid black">Variable \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">B coefficient \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Standard error \t\t\t\t\t\t\n \t\t\t\t</th><th class="td" title="table-head " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">p value \t\t\t\t\t\t\n \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Year of publication \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.345 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.420 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.43 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Number of authors \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1.169 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1.073 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.29 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Number of faculty \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">−3.988 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">1.995 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.06 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Sample size \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.003 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.009 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.73 \t\t\t\t\t\t\n \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Presence of author with Masters or PhD degree \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">10.310 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">4.452 \t\t\t\t\t\t\n \t\t\t\t</td><td class="td" title="table-entry " align="char" valign="top">0.03 \t\t\t\t\t\t\n \t\t\t\t</td></tr></tbody></table> """ ] "imagenFichero" => array:1 [ 0 => "xTab1306370.png" ] ] ] ] "descripcion" => array:1 [ "en" => "Adjusted effect of the variables on report completeness for observational studies published in RCA between 2000 and 2013 (n=23)." ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:46 [ 0 => array:3 [ "identificador" => "bib0235" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tools for assessing quality and susceptibility to bias in observational studies in epidemiology: a systematic review and annotated bibliography" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "S. 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Scientific and Technological Research

¿Es completo el reporte de los estudios observacionales publicados en la Revista Colombiana de Anestesiología? estudio de corte transversal

Mary Bravo-Peñaa, Luis Barona-Fonga, Julio Campo-Lópeza, Yeni Arroyaveb, José Andrés Calvachea,c,

Corresponding author

jacalvache@gmail.com

Corresponding author at: Departamento de Anestesiología, Hospital Universitario San José, Cra 6N.° 10N-142, tercer piso, Popayán, Colombia.

a Department of Anesthesiology, Universidad del Cauca, Popayán, Colombia

b Department of Surgery, Universidad del Cauca, Popayán, Colombia

c Department of Anesthesiology, Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands

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          "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Selection of the studies included &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>23&#41;&#46;</p>"
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Observational scientific research describes and analyses reality without intervening&#44;<a class="elsevierStyleCrossRef" href="#bib0235"><span class="elsevierStyleSup">1</span></a> and does not establish definitive causal relationships&#44; but it provides scientific bases regarding the health&#47;disease process and guides future research&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Bearing in mind that in various settings there are implications that preclude intervention &#40;such as studies on the safety of pharmacological or non-pharmacological interventions&#41;&#44; observational studies account for the majority of publications in the area of health&#46;<a class="elsevierStyleCrossRef" href="#bib0240"><span class="elsevierStyleSup">2</span></a> These are lower-cost studies&#44; easier to design and perform&#44; and useful for healthcare planning and administration&#46;<a class="elsevierStyleCrossRef" href="#bib0245"><span class="elsevierStyleSup">3</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">The STROBE statement &#40;<span class="elsevierStyleItalic">Strengthening the Reporting of Observational Studies in Epidemiology</span>&#41; was designed in 2004 in Bristol&#44; United Kingdom&#44; and published in 2007<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">4</span></a> with the aim of improving observational research reporting&#46; A framework comprising 22 items was developed with the goal of making observational results truly useful by means of an appropriate reporting of cohort&#44; case&#8211;control and cross-sectional studies&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">4</span></a> The three research designs share 18 of the 22 items in the Statement&#44; whereas the other 4 are specific for each&#46; The items include the Title&#44; Abstract&#44; Introduction&#44; Methodology&#44; Results and Discussion sections&#46;<a class="elsevierStyleCrossRef" href="#bib0250"><span class="elsevierStyleSup">4</span></a> The <span class="elsevierStyleItalic">STROBE</span> statement is not a model for conducting an observational study and it does not assess the quality of a study directly&#46; Rather&#44; it is more a completeness guideline for authors or readers&#44; and has been used to assess this characteristic in various medical disciplines&#46;<a class="elsevierStyleCrossRefs" href="#bib0255"><span class="elsevierStyleSup">5&#8211;12</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">The Colombian Journal of Anaesthesiology &#40;RCA&#41; was published for the first time in September 1973&#59; the first few articles were narrative reviews related to the practice of anaesthesiology but the journal later became a medium for disseminating original research results&#46; At present&#44; it is the official communication medium of the Colombian Society of Anaesthesiology and the main medium for the dissemination of research in anaesthesiology and related areas in Colombia&#46; In 1999&#44; the Cochrane Collaboration found that RCA is the Colombian journal that publishes the largest number of reports on intervention studies&#44; systematic reviews and meta-analyses&#46;<a class="elsevierStyleCrossRef" href="#bib0295"><span class="elsevierStyleSup">13</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">Recently&#44; RCA adopted the guidelines of the EQUATOR network &#40;<span class="elsevierStyleItalic">Enhancing the QUAlity and Transparency Of health Research</span>&#41;&#44; which includes the <span class="elsevierStyleItalic">STROBE</span> statement for its editorial process as well as a firm suggestion about its use for its authors&#46;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">14</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">The main objective of this study was to determine the completeness of reporting of observational studies published in RCA between 2000 and 2013&#44; using the <span class="elsevierStyleItalic">STROBE</span> statement&#46; Additionally&#44; to analyse the completeness of observational study reporting before and after the publication of the <span class="elsevierStyleItalic">STROBE</span> statement&#44; quantify the trend&#44; and establish recommendations regarding complete reporting of observational research in anaesthesiology in Colombia&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Methodology</span><p id="par0035" class="elsevierStylePara elsevierViewall">Cross-sectional observational study&#46; The subjects for the analysis were all the observational studies published in RCA between 2000 &#40;volume 28&#41; and 2013 &#40;volume 41&#41;&#46; The RCA archive hosted in the website and the database of the tables of content and abstracts in <span class="elsevierStyleItalic">Science Direct</span> were initially explored&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Studies classified as &#8220;observational&#8221; were those defined as such by their authors&#58; cohort studies&#44; case&#8211;control studies and cross-sectional &#40;or prevalence&#41; studies&#44; and they were initially classified based on the evaluation of each abstract&#46; Studies that were excluded were those without a clear&#44; well-defined methodological design&#44; editorials&#44; letters to the editor&#44; reflection articles&#44; narrative or systematic reviews of the literature&#44; case reports and case series&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">A total of 55 observational studies were identified&#46; Because of the exploratory nature of the study&#44; a random selection of 40&#37; &#40;22 studies&#41; was made&#44; and annual representation in the sample to analyse was ensured by means of proportional fixation by year&#46; Based on reports on prior publications&#44; the sample size was estimated using a completeness proportion of 60&#37;&#44; 15&#37; accuracy and 95&#37; CI&#44; for <span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>24&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">An assessment tool developed on the basis of the <span class="elsevierStyleItalic">STROBE</span> statement and aimed at evaluating the reporting completeness for each study was applied&#46; This tool and minor modifications thereof have ween widely used in the literature for similar purposes&#46;<a class="elsevierStyleCrossRefs" href="#bib0250"><span class="elsevierStyleSup">4&#8211;12</span></a></p><p id="par0055" class="elsevierStylePara elsevierViewall">The selected studies were divided into 2 groups and two researchers already familiar with the research methodology&#44; the health research designs and the STROBE initiative were assigned to each group &#40;Group 1&#58; JC-YA&#44; Group 2&#58; MB-LB&#41;&#46; Each researcher&#44; working separately&#44; applied the list of items to each study in order to determine whether they were &#8220;met&#8221;&#44; &#8220;unmet&#8221; or did &#8220;not apply&#8221;&#44; in accordance with the specific type of design&#46; Regular follow-up meetings were held&#44; during which the researchers shared their results&#44; reviewed and discussed the cases for which the assessment was inconclusive&#46; In cases of difficulty&#44; the rating was discussed individually with a research advisor &#40;JAC&#41;&#46;</p><p id="par0060" class="elsevierStylePara elsevierViewall">The dependent variable &#40;primary outcome&#41; was completeness of the report of each study assessed&#46; Additionally&#44; other variables were explored&#44; such as sample size&#44; number of authors&#44; number of professors&#44; presence or not of individuals with Masters or PhD degrees in the research team&#44; and the year of publication&#46;</p><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Statistical analysis</span><p id="par0065" class="elsevierStylePara elsevierViewall">All statistical analyses were made using the SPSS 21&#46;0 and R software package&#46;<a class="elsevierStyleCrossRef" href="#bib0305"><span class="elsevierStyleSup">15</span></a> Completeness rating for each study was the sum of all the items in the assessment&#46; Considering that the total number of variables assessed was different for each research design &#40;cohort&#44; case&#8211;controls&#44; and cross-sectional&#41; the individual final result was weighted&#44; and the median rating between the two reviewers and the range as a measure of scatter were estimated&#46; The degree of agreement regarding completeness rating was analysed using the intra-class correlation coefficient &#40;ICC&#41;&#46; This agreement was assessed for study segments and also globally&#46;</p><p id="par0070" class="elsevierStylePara elsevierViewall">The general description of the results was made using descriptive techniques in accordance with the nature of each variable&#46; Non-parametric tests were used for univariate contrasting &#40;Mann&#8211;Whitney <span class="elsevierStyleItalic">U</span> Test&#41; using report completeness as the dependent variable&#46;</p><p id="par0075" class="elsevierStylePara elsevierViewall">A time series analysis was made using an autoregressive integrated moving average &#40;ARIMA&#41; model that allows to assess trends before and after an intervention&#46; This methodology considers multiple evaluation points before and after an intervention and the existing autocorrelation between those points&#46;<a class="elsevierStyleCrossRefs" href="#bib0310"><span class="elsevierStyleSup">16&#44;17</span></a> Pre-intervention &#40;2007&#58; year of the <span class="elsevierStyleItalic">STROBE</span> initiative publication&#41; and post-intervention periods were used&#46; Their results are presented as the difference in the slope of the regression line before and after the intervention&#46; Additionally&#44; the effect of the intervention for 2009&#44; 2012 and 2013 is also presented&#46; Statistical significance was predefined as a <span class="elsevierStyleItalic">p</span> value of 0&#46;05&#46;</p><p id="par0080" class="elsevierStylePara elsevierViewall">Finally&#44; a multiple linear regression model was developed in which the degree of completeness was considered as the outcome&#44; and the year of publication&#44; sample size&#44; the number of authors&#44; the number of professors and the presence or absence of individuals with masters degrees or PhDs in the research team were considered as independent variables&#46; The results are presented as the regression coefficient and their corresponding <span class="elsevierStyleItalic">p</span> values&#46; The adjustment of this model was valued using the graphic residual analysis&#46;</p></span></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Results</span><p id="par0085" class="elsevierStylePara elsevierViewall">Overall&#44; 22 observational studies published in RCA between 2000 and 2013 were analysed&#46;<a class="elsevierStyleCrossRefs" href="#bib0320"><span class="elsevierStyleSup">18&#8211;39</span></a> One of them was reported as a two-phase study&#44; so it was divided separately for a total of 23 &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; <a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> shows the general characteristics of the studies included&#46; The median overall completeness of the items in the STROBE statement was 57&#37;&#44; 95&#37;CI &#40;48&#8211;66&#37;&#41;&#46; The sections for which greater completeness was documented were the Title and the Introduction &#40;89&#37; each&#41;&#46; Completeness for each section of the research articles is shown in <a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0090" class="elsevierStylePara elsevierViewall"><a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a> shows completeness results by reviewer and article sections&#44; and the degree of agreement between reviewer pairs by group&#46;</p><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0095" class="elsevierStylePara elsevierViewall">The overall completeness trend is shown in graph form &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41; for before and after the publication of the STROBE strategy&#46; The linear equation for completeness is shown for each of the sections as a function of the year of publication&#46; Greater rating variability was found for the post-STROBE period&#46; The slope of the straight line for the time period before the intervention was 0&#46;85&#46; The difference in the slope of the line between the before and after time periods was &#8722;0&#46;47 &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;709&#41;&#46; Change coefficients in the slope of the line for 2009&#44; 2021 and 2013 were&#44; respectively&#44; &#8722;3&#46;2 &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;698&#41;&#44; &#8722;5&#46;1 &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;628&#41; and &#8722;7&#46;5 &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;626&#41;&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0100" class="elsevierStylePara elsevierViewall">The completeness of the reports that included the presence of an author with a Master&#39;s or PhD degree was higher &#40;<span class="elsevierStyleItalic">p</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#46;03&#41;&#46; The adjusted effect of the study variables on completeness is shown in <a class="elsevierStyleCrossRef" href="#tbl0015">Table 3</a>&#46;</p><elsevierMultimedia ident="tbl0015"></elsevierMultimedia></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Discussion</span><p id="par0105" class="elsevierStylePara elsevierViewall">The main findings of this study are&#44; first&#44; that completeness of observational studies published in RCA is 57&#37;&#44; and the Title and Introduction are the sections with the greatest completeness&#44; while Methodology and Results are the ones with the greatest deficiencies&#46; Second&#44; during the 13-year study period there is a very slow increase in completeness&#44; and there is no evidence that the publication of the STROBE statement in 2007 had any effect on completeness for RCA&#46;</p><p id="par0110" class="elsevierStylePara elsevierViewall">The completeness of observational studies is similar to that reported by other authors&#46; Several research studies have documented completeness ranges of 30&#8211;85&#37;&#46;<a class="elsevierStyleCrossRefs" href="#bib0255"><span class="elsevierStyleSup">5&#44;6&#44;9&#44;10&#44;12&#44;40</span></a> In 2011&#44; Poorolajal et al&#46;&#44; analysed observational studies in the <span class="elsevierStyleItalic">New England Journal of Medicine&#44; Journal of the American Medical Association&#44; Lancet&#44; British Medical Journal&#44; Archives of Internal Medicine&#44; and the Canadian Medical Association Journal</span>&#44; and found an overall compliance of 69&#37; &#40;95&#37; CI 59&#8211;79&#37;&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0280"><span class="elsevierStyleSup">10</span></a> In 2013&#44; Bastuji-Garin et al&#46;&#44; published a similar study in which they analysed observational studies of four European dermatology journals&#46; The mean rating using the <span class="elsevierStyleItalic">STROBE</span> tool was 57&#37; &#40;range 18&#8211;98&#37;&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">9</span></a> Percentages vary in specific areas of knowledge&#44; from satisfactory quality of reporting&#44; like in the study by Papathanasiou et al&#46; in oncology which included publications between 2008 and 2009&#44; where completeness reported ranged between 70 and 90&#37;&#44;<a class="elsevierStyleCrossRef" href="#bib0265"><span class="elsevierStyleSup">7</span></a> all the way to low proportions&#44; such as those reported by Sorensen et al&#46;&#44; where compliance in observational studies on hand surgery published between 2005 and 2011 was 38&#37;&#44; with a range between 10 and 54&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0260"><span class="elsevierStyleSup">6</span></a> This might be influenced by the range of time during which the studies were developed in relation to the time of publication of the statement&#44; and the awareness of scientists and authors regarding the importance of completeness when it comes to disseminating information&#46; Despite having analysed 40&#37; of the studies&#44; the accuracy of our completeness estimation had a 95&#37; CI of 48&#8211;66&#37;&#44; leaving an impression of the need for future improvement&#46;</p><p id="par0115" class="elsevierStylePara elsevierViewall">Authors like Fung and Langan et al&#46;&#44; found that the items with the highest percentage of compliance were the Title&#44; the Introduction and the Abstract&#46; Of the publications analysed by Fung&#44; 100&#37; met the criteria established by <span class="elsevierStyleItalic">STROBE</span> for the Introduction&#44; 86&#37; and 93&#37; for the Title and the Abstract&#44; respectively&#46; Compliance found by Langan et al&#46; was 97&#37; for the Introduction&#44; 87&#37; for the Title and 93&#37; for the Abstract&#46;<a class="elsevierStyleCrossRefs" href="#bib0270"><span class="elsevierStyleSup">8&#44;41</span></a> Consistent with the literature mentioned above&#44; for RCA publications we found an 89&#37; compliance with the <span class="elsevierStyleItalic">STROBE</span> guidelines for the Title and the Abstract&#46;</p><p id="par0120" class="elsevierStylePara elsevierViewall">The sections with the lowest completeness ratings were Methodology and Results&#44; and this is consistent with results from similar studies&#46; Galera et al&#46;&#44; found that none of the articles reviewed were in compliance with the items recommended for Methods and Results&#46;<a class="elsevierStyleCrossRef" href="#bib0290"><span class="elsevierStyleSup">12</span></a> In the work by Fung&#44; reporting completeness for the section on Materials and Methods varied&#44; with item ratings ranging between 7&#37; and 97&#37;&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">8</span></a> Low completeness for these sections may be related with their degree of complexity&#46; For example&#44; the methodology section requires detailed knowledge of epidemiology and biostatistics&#44; which is not always widely available or accessible&#46; It is worth noting that the section on Methods and Results had the lowest scores for domain agreement between reviewers &#40;ICC of less than a 0&#46;5&#41;&#46; This fact reinforces the hypothesis that these are sections of a manuscript that require prior training and sound knowledge of research methodology both for writing as well as for analytical purposes&#46;</p><p id="par0125" class="elsevierStylePara elsevierViewall">During the 13 years selected for this assessment&#44; there was evidence of a slight trend towards improved report completeness&#46; This trend is quite slow &#40;0&#46;4 a 0&#46;8&#37; per year&#41;&#46; In their study&#44; Bastuji-Garin et al&#46; show an increase during the study period &#40;2004&#8211;2010&#41; of close to 2&#37; per year&#46;<a class="elsevierStyleCrossRef" href="#bib0275"><span class="elsevierStyleSup">9</span></a> The results of this analysis must be taken cautiously because of the great variability found during the post-<span class="elsevierStyleItalic">STROBE</span> period in the overall rating for certain studies&#46; Additional studies regarding RCA have found that&#44; over time&#44; the risk of bias of the reported studies has diminished&#46;<a class="elsevierStyleCrossRef" href="#bib0440"><span class="elsevierStyleSup">42</span></a></p><p id="par0130" class="elsevierStylePara elsevierViewall">No evidence was found in this study in the sense that the publication of <span class="elsevierStyleItalic">STROBE</span> had any significant impact on the completeness of the observational research published in RCA&#46; This fact has been replicated by other authors&#46;<a class="elsevierStyleCrossRef" href="#bib0270"><span class="elsevierStyleSup">8</span></a> Despite the publication of the strategy in 2007 and of its wide dissemination in the scientific media&#44; many publications and journals were late in adopting it&#46; RCA adopted the guidelines of the EQUATOR network&#44; including STROBE&#44; in 2013&#46;<a class="elsevierStyleCrossRef" href="#bib0300"><span class="elsevierStyleSup">14</span></a> With the use of other statements like CONSORT there has been a consistent increase in the completeness of published reports&#46;<a class="elsevierStyleCrossRef" href="#bib0445"><span class="elsevierStyleSup">43</span></a> Fortunately&#44; the scientific community in general is increasingly attaching greater importance to research completeness as a strategy to improve reproducibility and increase its validity&#46;<a class="elsevierStyleCrossRefs" href="#bib0450"><span class="elsevierStyleSup">44&#8211;46</span></a></p><p id="par0135" class="elsevierStylePara elsevierViewall">The effect of some variables on the completeness of study reports was almost negligible&#46; Only the presence of researchers with Masters and&#47;or PhD degrees increased report completeness significantly &#40;by approximately 10&#37;&#41;&#46; Although this is not a statistically significant increase and requires a critical analysis&#44; it is plausible&#46; Moreover&#44; the size of the study sample may have lowered the power of the study for detecting actual differences &#40;type II error&#41;&#46;</p><p id="par0140" class="elsevierStylePara elsevierViewall">As far as we know&#44; this is the first study to analyse the completeness of observational research reports in anaesthesiology and other areas in Colombia&#46; Noteworthy among the strengths of the study are the thorough search of observational studies in RCA&#44; the analysis of completeness performed by 4 independent reviewers&#44; and the participation of an arbitrator to solve discrepancies&#46; This resulted in a lower possibility of selection and information bias&#46; The main limitation was failure to study the entire population of observational studies&#44; which undermined the confidence of our overall completeness estimate&#46; However&#44; our objective was to document its existence in order to promote improvement&#46; Below are the main recommendations of this study&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0100">Ethical disclosures</span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0105">Protection of human and animal subjects</span><p id="par0145" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0110">Confidentiality of data</span><p id="par0150" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0115">Right to privacy and informed consent</span><p id="par0155" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0120">Funding</span><p id="par0160" class="elsevierStylePara elsevierViewall">None&#46;</p></span><span id="sec0055" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0125">Conflicts of interest</span><p id="par0165" class="elsevierStylePara elsevierViewall">None declared&#46;</p></span></span>"
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    "fechaRecibido" => "2016-05-04"
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    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec784517"
          "palabras" => array:5 [
            0 => "Observational study"
            1 => "Anesthesiology"
            2 => "Epidemiologic studies"
            3 => "Medical education"
            4 => "Statistical analysis"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec784516"
          "palabras" => array:5 [
            0 => "Estudio observacional"
            1 => "Anestesiolog&#237;a"
            2 => "Estudios epidemiol&#243;gicos"
            3 => "Educaci&#243;n m&#233;dica"
            4 => "An&#225;lisis estad&#237;stico"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:3 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The STROBE statement &#40;Strengthening the Reporting of Observational Studies in Epidemiology&#41;&#44; consisting of 22 points&#44; was published in 2007 with the aim of improving the reporting of observational research&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Objective</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To determine the completeness of reporting of observational studies published in the Colombian Journal of Anaesthesiology between 2000 and 2013 using STROBE&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Cross-sectional study&#46; The units of analysis were observational studies published in Colombian Journal of Anesthesiology between 2000 &#40;volume 28&#41; and 2013 &#40;volume 41&#41;&#46; Of the randomly selected studies&#44; 40&#37; were included&#46; The primary outcome was the completeness of the report of each study&#46; Using two groups&#44; the researchers applied the STROBE statement independently&#44; supported by an arbitrator&#46; Descriptive analyses&#44; time series analyses and multiple linear regression analyses were used&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Overall&#44; 55 studies were identified and 22 &#40;40&#37;&#41; were randomly chosen&#46; The median overall completeness according to STROBE was 57&#37;&#44; 95&#37; CI &#40;48&#8211;66&#37;&#41;&#46; Items with higher completeness in the reports were the Title and Introduction &#40;89&#37; each&#41;&#44; followed by Methods 53&#37;&#44; Results 50&#37;&#44; and Discussion 58&#37;&#46; There were no significant differences between before and after the publication of STROBE&#46;</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Conclusion</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The completeness of reporting of observational studies in the Colombian Journal of Anaesthesiology is close to 60&#37;&#44; according to results worldwide&#46; No change was found as a result of the publication of the STROBE Statement in 2007&#46;</p></span>"
        "secciones" => array:5 [
          0 => array:2 [
            "identificador" => "abst0005"
            "titulo" => "Introduction"
          ]
          1 => array:2 [
            "identificador" => "abst0010"
            "titulo" => "Objective"
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          2 => array:2 [
            "identificador" => "abst0015"
            "titulo" => "Methods"
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          3 => array:2 [
            "identificador" => "abst0020"
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          4 => array:2 [
            "identificador" => "abst0025"
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      "es" => array:3 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Introducci&#243;n</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La declaraci&#243;n STROBE &#40;<span class="elsevierStyleItalic">Strenghtening the Reporting of Observational Studies in Epidemiology</span>&#41; se public&#243; en el 2007 con el objetivo de mejorar el reporte de la investigaci&#243;n de tipo observacional&#44; consta de 22 puntos&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Objetivo</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Determinar la completitud del reporte de estudios observacionales publicados en la Revista Colombiana de Anestesiolog&#237;a entre el a&#241;o 2000 al 2013 mediante STROBE&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">M&#233;todos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Estudio observacional de corte transversal&#46; La unidad de an&#225;lisis fueron los estudios observacionales publicados en la Revista Colombiana de Anestesiolog&#237;a desde el a&#241;o 2000 &#40;volumen 28&#41; hasta el a&#241;o 2013 &#40;volumen 41&#41;&#46; Se incluy&#243; un 40&#37; del total de estudios seleccionados aleatoriamente&#46; El desenlace primario fue la completitud del reporte de cada estudio&#46; Mediante dos grupos&#44; los investigadores aplicaron la declaraci&#243;n STROBE de forma independiente con el apoyo de un &#225;rbitro&#46; Se utiliz&#243; an&#225;lisis descriptivo&#44; an&#225;lisis de series temporales y regresi&#243;n lineal m&#250;ltiple&#46;</p></span> <span id="abst0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Resultados</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Se identificaron 55 estudios y se escogieron al azar 22 &#40;40&#37;&#41;&#46; La mediana de completitud global de STROBE fue de 57&#37; IC95&#37; &#40;48&#37;-66&#37;&#41;&#46; Los &#237;tems con mayor completitud de los reportes fueron en el t&#237;tulo y la introducci&#243;n &#40;89&#37; cada uno&#41;&#44; m&#233;todos&#58; 53&#37;&#44; Resultados 50&#37;&#44; discusi&#243;n 58&#37;&#46; No se encontr&#243; diferencias significativas entre el periodo pre y post publicaci&#243;n de STROBE&#46;</p></span> <span id="abst0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conclusi&#243;n</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">La completitud del reporte de los estudio observacionales de la Revista Colombiana de Anestesiolog&#237;a es cercana al 60&#37;&#44; acorde con resultados a nivel mundial&#46; No present&#243; cambios con la publicaci&#243;n de la declaraci&#243;n STROBE en el 2007&#46;</p></span>"
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            "titulo" => "Conclusi&#243;n"
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    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0015">Please cite this article as&#58; Bravo-Pe&#241;a M&#44; Barona-Fong L&#44; Campo-L&#243;pez J&#44; Arroyave Y&#44; Calvache JA&#46; &#191;Es completo el reporte de los estudios observacionales publicados en la Revista Colombiana de Anestesiolog&#237;a&#63; Estudio de corte transversal&#46; Rev Colomb Anestesiol&#46; 2017&#59;45&#58;31&#8211;38&#46;</p>"
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          "en" => "<p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">Selection of the studies included &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>23&#41;&#46;</p>"
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          "en" => "<p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">Completeness for research article sections &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>23&#41;&#46;</p>"
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        "etiqueta" => "Fig&#46; 3"
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          "en" => "<p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Overall annual completeness trend of the observational studies published in RCA between 2000 and 2013 &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>23&#41;&#46; Note&#58; The straight line equations in the upper part represent the proportion of increased completeness by year during the two periods&#46; During the first period&#44; the increase &#40;B coefficient&#41; was 0&#46;8&#37;&#44; and during the second period&#44; the increase was 0&#46;4&#37;&#46;</p>"
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                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Frequency &#40;&#37;&#41;<br>Mean <span class="elsevierStyleItalic">&#956;</span><span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>1<span class="elsevierStyleHsp" style=""></span>SD<br>Median &#91;IQR&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleItalic">Year of publication</span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>2000&#8211;2003&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">7 &#40;30&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>2004&#8211;2007&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5 &#40;22&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>2008&#8211;2011&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">5 &#40;22&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleHsp" style=""></span>2012&#8211;2013&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">6 &#40;26&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Total number of authors</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top"><span class="elsevierStyleItalic">&#956;</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3&#46;7<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " align="" valign="top">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="left" valign="top">Median<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>3 &#91;3&#8211;5&#93;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Number of faculty</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Study sample size</span>&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="2" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top"><span class="elsevierStyleItalic">Presence of author with masters degree or PhD</span>&nbsp;\t\t\t\t\t\t\n
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                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Group 1 &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>12&#41;</th><th class="td" title="table-head  " colspan="3" align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Group 2 &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>11&#41;</th></tr><tr title="table-row"><th class="td" title="table-head  " align="" valign="top" scope="col" style="border-bottom: 2px solid black">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Reviewer 1&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Agreement<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Reviewer 1&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Reviewer 2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th><th class="td" title="table-head  " align="center" valign="top" scope="col" style="border-bottom: 2px solid black">Agreement<a class="elsevierStyleCrossRef" href="#tblfn0005"><span class="elsevierStyleSup">&#42;</span></a>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Title&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">1&#46;00&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">77&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">81&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;86&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Introduction&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">95&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;64&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">86&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">90&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;77&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Methods&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">64&#46;5&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#46;0&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;53&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">54&#46;7&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">46&#46;4&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;56&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Results&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">33&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;28&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">45&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;56&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Discussion&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">73&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">56&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;53&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">42&#46;3&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">59&#46;6&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;45&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td" title="table-entry  " colspan="7" align="left" valign="top"><span class="elsevierStyleVsp" style="height:0.5px"></span></td></tr><tr title="table-row"><td class="td-with-role" title="table-entry ; entry_with_role_rowhead " align="left" valign="top">Total&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">70&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#46;8&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top"><span class="elsevierStyleBold">0&#46;49</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">55&#46;9&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">52&#46;2&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top"><span class="elsevierStyleBold">0&#46;59</span>&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
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          "en" => "<p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Completeness rated by each reviewer by article sections and degree of agreement between reviewer pairs by group &#40;<span class="elsevierStyleItalic">n</span><span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>23&#41;&#46;</p>"
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;43&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;29&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;06&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;009&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t</td><td class="td" title="table-entry  " align="char" valign="top">0&#46;03&nbsp;\t\t\t\t\t\t\n
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          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:46 [
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                    0 => array:2 [
                      "titulo" => "Tools for assessing quality and susceptibility to bias in observational studies in epidemiology&#58; a systematic review and annotated bibliography"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46; Sanderson"
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                            2 => "J&#46;P&#46; Higgins"
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                    0 => array:2 [
                      "doi" => "10.1093/ije/dym018"
                      "Revista" => array:6 [
                        "tituloSerie" => "Int J Epidemiol"
                        "fecha" => "2007"
                        "volumen" => "36"
                        "paginaInicial" => "666"
                        "paginaFinal" => "676"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17470488"
                            "web" => "Medline"
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            1 => array:3 [
              "identificador" => "bib0240"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiologic study design"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46; Hernandez"
                            1 => "F&#46; Garrido"
                            2 => "S&#46; L&#243;pez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Salud Publica Mex"
                        "fecha" => "2000"
                        "volumen" => "42"
                        "paginaInicial" => "144"
                        "paginaFinal" => "154"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10893985"
                            "web" => "Medline"
                          ]
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                      ]
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            2 => array:3 [
              "identificador" => "bib0245"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Estudios observacionales&#46; Los dise&#241;os utilizados con mayor frecuencia en investigaci&#243;n cl&#237;nica"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Manterola"
                            1 => "T&#46; Otzen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Int J Morphol"
                        "fecha" => "2014"
                        "volumen" => "32"
                        "paginaInicial" => "634"
                        "paginaFinal" => "645"
                      ]
                    ]
                  ]
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            3 => array:3 [
              "identificador" => "bib0250"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The strengthening the reporting of observational studies in epidemiology &#91;STROBE&#93; statement&#58; guidelines for reporting observational studies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "E&#46; Von Elm"
                            1 => "D&#46;G&#46; Altman"
                            2 => "M&#46; Egger"
                            3 => "S&#46;J&#46; Pocock"
                            4 => "P&#46;C&#46; Gotzsche"
                            5 => "J&#46;P&#46; Vandenbroucke"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Gac Sanit"
                        "fecha" => "2008"
                        "volumen" => "22"
                        "paginaInicial" => "144"
                        "paginaFinal" => "150"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18420014"
                            "web" => "Medline"
                          ]
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                  ]
                ]
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            4 => array:3 [
              "identificador" => "bib0255"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Uses and misuses of the STROBE statement&#58; bibliographic study"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "B&#46;R&#46; Da Costa"
                            1 => "M&#46; Cevallos"
                            2 => "D&#46;G&#46; Altman"
                            3 => "A&#46;W&#46; Rutjes"
                            4 => "M&#46; Egger"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/bmjopen-2010-000048"
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                        "tituloSerie" => "BMJ Open"
                        "fecha" => "2011"
                        "volumen" => "1"
                        "paginaInicial" => "e000048"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22021739"
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            5 => array:3 [
              "identificador" => "bib0260"
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              "referencia" => array:1 [
                0 => array:3 [
                  "comentario" => "1584&#8211;9 e2"
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Using the strengthening the reporting of observational studies in epidemiology &#40;STROBE&#41; statement to assess reporting of observational trials in hand surgery"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46;A&#46; Sorensen"
                            1 => "R&#46;D&#46; Wojahn"
                            2 => "M&#46;C&#46; Manske"
                            3 => "R&#46;P&#46; Calfee"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.jhsa.2013.05.039"
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                        "tituloSerie" => "J Hand Surg Am"
                        "fecha" => "2013"
                        "volumen" => "38"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23910379"
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            6 => array:3 [
              "identificador" => "bib0265"
              "etiqueta" => "7"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessing the quality of reporting of observational studies in cancer"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;A&#46; Papathanasiou"
                            1 => "E&#46; Zintzaras"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.annepidem.2009.09.007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Epidemiol"
                        "fecha" => "2009"
                        "volumen" => "20"
                        "paginaInicial" => "67"
                        "paginaFinal" => "73"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20006277"
                            "web" => "Medline"
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                      ]
                    ]
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                ]
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            ]
            7 => array:3 [
              "identificador" => "bib0270"
              "etiqueta" => "8"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Applying the CONSORT and STROBE statements to evaluate the reporting quality of neovascular age-related macular degeneration studies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46;E&#46; Fung"
                            1 => "R&#46; Palanki"
                            2 => "S&#46;J&#46; Bakri"
                            3 => "E&#46; Depperschmidt"
                            4 => "A&#46; Gibson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ophtha.2008.09.014"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ophthalmology"
                        "fecha" => "2009"
                        "volumen" => "116"
                        "paginaInicial" => "286"
                        "paginaFinal" => "296"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19091408"
                            "web" => "Medline"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Impact of STROBE statement publication on quality of observational study reporting&#58; interrupted time series versus before&#8211;after analysis"
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                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "S&#46; Bastuji-Garin"
                            1 => "E&#46; Sbidian"
                            2 => "C&#46; Gaudy-Marqueste"
                            3 => "E&#46; Ferrat"
                            4 => "J&#46;C&#46; Roujeau"
                            5 => "M&#46;A&#46; Richard"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1371/journal.pone.0064733"
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                        "tituloSerie" => "PLOS ONE"
                        "fecha" => "2013"
                        "volumen" => "8"
                        "paginaInicial" => "e64733"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23990867"
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                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Quality of cohort studies reporting post the strengthening the reporting of observational studies in epidemiology &#40;STROBE&#41; statement"
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                        0 => array:2 [
                          "etal" => false
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Article information

ISSN: 22562087
Original language: English

DOI:10.1016/j.rcae.2016.11.017

The statistics are updated each day

Year/Month	Html	Pdf	Total

2024 November	4	2	6
2024 October	10	11	21
2024 September	11	5	16
2024 August	3	3	6
2024 July	10	4	14
2024 June	13	3	16
2024 May	19	4	23
2024 April	29	2	31
2024 March	19	5	24
2024 February	11	7	18
2024 January	27	9	36
2023 December	21	9	30
2023 November	3	10	13
2023 October	15	12	27
2023 September	15	4	19
2023 August	11	2	13
2023 July	7	4	11
2023 June	14	0	14
2023 May	13	4	17
2023 April	7	2	9
2023 March	5	1	6
2023 February	12	1	13
2023 January	8	4	12
2022 December	13	2	15
2022 November	13	6	19
2022 October	13	7	20
2022 September	13	7	20
2022 August	11	10	21
2022 July	10	7	17
2022 June	9	6	15
2022 May	7	22	29
2022 April	16	4	20
2022 March	9	7	16
2022 February	10	4	14
2022 January	7	4	11
2021 December	12	9	21
2021 November	13	8	21
2021 October	21	8	29
2021 September	15	9	24
2021 August	9	10	19
2021 July	10	5	15
2021 June	7	4	11
2021 May	16	4	20
2021 April	16	22	38
2021 March	13	6	19
2021 February	7	7	14
2021 January	14	9	23
2020 December	6	7	13
2020 November	7	6	13
2020 October	7	5	12
2020 September	10	5	15
2020 August	10	7	17
2020 July	8	8	16
2020 June	4	6	10
2020 May	7	3	10
2020 April	5	4	9
2020 March	2	1	3
2020 February	7	3	10
2020 January	8	3	11
2019 December	11	3	14
2019 November	4	1	5
2019 October	7	1	8
2019 September	4	2	6
2019 August	1	1	2
2019 July	4	5	9
2019 June	1	1	2
2019 May	2	11	13
2018 November	1	0	1
2018 September	1	0	1
2018 June	9	1	10
2018 May	35	3	38
2018 April	37	9	46
2018 March	48	9	57
2018 February	16	7	23
2018 January	34	4	38
2017 December	30	8	38
2017 November	23	1	24
2017 October	30	10	40
2017 September	22	9	31
2017 August	13	4	17
2017 July	15	5	20
2017 June	43	7	50
2017 May	48	9	57
2017 April	65	16	81
2017 March	47	9	56
2017 February	28	3	31
2017 January	45	10	55
2016 December	8	7	15

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