Editorial
The ABC of diabetes registries
El ABC de los registros de diabetes
Jannet Svensson
Associated professor, Department of Pediatrics and Adolescents Herlev & Gentofte University hospital Borgmester Ib Juuls vej 1, 2730 Herlev, Denmark
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"descripcion" => array:1 [ "en" => "<p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Distribution of BMI for age in studied children compared with WHO standard.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Huda Al Hourani, Manar Atoum, Foad Alzoughool, Islam Al-Shami" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Huda" "apellidos" => "Al Hourani" ] 1 => array:2 [ "nombre" => "Manar" "apellidos" => "Atoum" ] 2 => array:2 [ "nombre" => "Foad" "apellidos" => "Alzoughool" ] 3 => array:2 [ "nombre" => "Islam" "apellidos" => "Al-Shami" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2530018021001207?idApp=UINPBA00004N" "url" => "/25300180/0000006800000008/v1_202112040843/S2530018021001207/v1_202112040843/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Editorial</span>" "titulo" => "The ABC of diabetes registries" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "525" "paginaFinal" => "526" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Jannet Svensson" "autores" => array:1 [ 0 => array:3 [ "nombre" => "Jannet" "apellidos" => "Svensson" "email" => array:1 [ 0 => "Jannet.Svensson@regionh.dk" ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Associated professor, Department of Pediatrics and Adolescents Herlev & Gentofte University hospital Borgmester Ib Juuls vej 1, 2730 Herlev, Denmark" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "El ABC de los registros de diabetes" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Childhood diabetes is a relatively common chronic disease in Europe, though its prevalence varies around the globe.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> Since worldwide variation in the incidence of childhood diabetes was first reported by the Diabetes Epidemiology Group in 1988 <a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a>, several international collaborations have been established, confirming very low yearly incidences in some countries in Africa and Asia (<5 cases/100.000) and very high levels (>30 cases/100.000) in some Scandinavian countries.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> While these incidence registries are widespread, those focusing on quality of care are less common, though a few have emerged since the early 1990’ies, leading to international benchmarking.<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3–6</span></a> Since glycated haemoglobin (HbA1c) is the best known predictor of long-term outcome and has been associated to the risk of psychiatric co-morbidity, it is also the most studied benchmarking factor.<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7–9</span></a> Indeed, benchmarking and registries have, by themselves, a positive influence on HbA1c trajectories. The first sign of the ability of <span class="elsevierStyleBold">Awareness</span> to create changes was seen in the Hvidoere study group, where HB Mortensen found his own clinic to have much higher HbA1c than many other centres in the group <a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a>. This led to several changes in the clinic and a substantial improvement in HbA1c from 1998 to 2005. Similarly, the power of awareness has also been demonstrated in Denmark and Sweden, where significant drops in HbA1c were seen after open benchmarking and a quality improvement program were initiated in 2005 and 2012, respectively.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">10,11</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">However, awareness alone does not always seem to work. In the Hvidoere study group, for example, only two centres improved their HbA1c from 1998 to 2005 and one reason for this could be <span class="elsevierStyleBold">Beliefs</span> about comparability. The Hvidoere study Group comprised 14 centres from around the world, with different resources and economies. If the best performing centres also had better educated population and better access to technology and health care providers, then the results may have seemed unobtainable for other clinics. This belief was challenged in Denmark by comparing all 16 diabetes clinics: the best performing centre had the lowest proportion of pump users and adjusting for socio-economic status did not substantially change the HbA1c ranking. Furthemore, no correlation was found between the number of visits in the clinic and HbA1c, nor when including phone contacts. The only parameter that contributed to explain the variation between centres was the number of daily blood glucose tests per patient. This suggests that training, target setting and education may be much more relevant than clinic resources.<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> It also indicates that it is important to believe that we all can improve. This is most clearly shown by SweDiabKids, where all centres have moved the national mean in HbA1c from 67 mmol/mol (8.2%) to 55 mmol/mol (7.3%) over a 20 year period, while the variation between clinics has diminished and is now the lowest in the world.<a class="elsevierStyleCrossRef" href="#bib0065"><span class="elsevierStyleSup">13</span></a> This achievement is remarkable and serves as a lighthouse for all working with clinical diabetes and diabetes registries.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Since the first publication of centre comparisons, there has been a worldwide search for factors explaining the differences and attempts to find the key to optimal glycaemic regulation. Structure and treatment have been in focus but the one factor that has been robustly associated with HbA1c is target setting.<a class="elsevierStyleCrossRef" href="#bib0070"><span class="elsevierStyleSup">14</span></a> Indeed, awareness and belief in change should be combined with <span class="elsevierStyleBold">Collaboration</span> and <span class="elsevierStyleBold">Commitment</span> from the health care providers. Furthermore, the individual centres need to look at their own performance with an open mind; they need to allocate time and resources to discuss goals and exchange ideas to create the basis for commitment within the teams. Small clinics may have an advantage where fewer health care providers need to agree on new targets or new ways to approach patients, whereas larger centres may have advantages in having more possibilities to be inspired through participation in conferences or international meetings. There is in fact some indication that new staff and new eyes may be beneficial.<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">15</span></a> Engagement and an optimistic view have been repeatedly mentioned as drivers of improvement in Sweden, England, Norway and Iceland, whenever I have been attending meetings where quality improvement has been on the agenda. In all these meetings the possibility to receive regular feedback, where you can follow your own results has been highlighted as extremely important.</p><p id="par0020" class="elsevierStylePara elsevierViewall">The study by Florentino Carral in recent issue of Endocrinología, Diabetes y Nutrición covering both adults and children confirms the positive effect of registries by showing, not just a substantial improvement in HbA1c but also a relatively low risk of microvascular complications in those with 10-19 years of diabetes. To what extent the results are due to awareness, changes in educational strategies, targets or treatment in the clinic remain to be documented. Nevertheless, building the registries is the first step in creating awareness and the positive results may increase the beliefs in the clinic that further improvement is possible. The creation of an optimistic and open-minded team may pave the way for collaboration and commitment.</p><p id="par0025" class="elsevierStylePara elsevierViewall">With the hope of continuous improvement for the benefit of patients in Cadiz and worldwide I hope more registries will emerge and more committed health care providers will believe in the power of educating our patients in self-care and in the use of the available treatment. I hope benchmarking within countries and between countries will lead to exchange of good ideas for improvement. Finally, I hope for the use of lower targets and more focus on psychological well-being by including person reported outcomes in registries will benefit patients worldwide.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2021-08-30" "fechaAceptado" => "2021-09-01" "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:15 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Worldwide estimates of incidence, prevalence and mortality of type 1 diabetes in children and adolescents: Results from the International Diabetes Federation Diabetes Atlas 9th edition" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "C.C. Patterson" 1 => "S. Karuranga" 2 => "P. Salpea" 3 => "P. Saeedi" 4 => "G. Dahlquist" 5 => "G. 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