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Inicio Endocrinología y Nutrición Medicina basada en la evidencia: nutrición en la obesidad
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Vol. 52. Issue S1.
Nutrición basada en la evidencia
Pages 102-109 (May 2005)
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Vol. 52. Issue S1.
Nutrición basada en la evidencia
Pages 102-109 (May 2005)
Nutrición basada en la evidencia
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Medicina basada en la evidencia: nutrición en la obesidad
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M.A. Rubio herreraa,
Corresponding author
marubio@futurnet.es

Correspondencia: Dr. M.A. Rubio. Servicio de Endocrinología y Nutrición. Hospital Clínico Universitario San Carlos. Martín Lagos, s/n. 28040 Madrid. España.
, C. Moreno loperab
a unidad De Nutrición Clínica Y Dietética. Servicio De Endocrinología Y Nutrición. Hospital Clínico Universitario San Carlos. Madrid. España
b Centro de Salud. Villaviciosa de Odón. Madrid. España
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El tratamiento dietético hipocalórico es la piedra angular del planteamiento terapéutico de la obesidad. En la mayoría de los estudios controlados la distribución de macronutrientes de la dieta no parece marcar la diferencia en términos de pérdida de peso. Así, por ejemplo, las dietas bajas en hidratos de carbono consiguen pérdidas significativas de peso frente a las dietas bajas en grasa, en períodos cortos de tiempo (6 meses), pero no hay diferencias tras un seguimiento a más largo plazo (12 meses). Existe un consenso general acerca de que una reducción energética comprendida entre 500 y 1.000 kcal diarias, respecto a la dieta habitual, consigue pérdidas promedio de 0,5 a 1 kg a la semana durante los primeros 6 meses de tratamiento, lo que representa una reducción entre el 5-10% del peso corporal, una proporción suficiente para atenuar el impacto de las comorbilidades asociadas con la obesidad. Pero los resultados a largo plazo (más de un año) con las dietas bajas en grasas son desalentadores (promedio de 0-3 kg), mientras que la seguridad de las dietas bajas en hidratos de carbono está pendiente de demostrar. En esta revisión se analizan los niveles de evidencia que diferentes tipos de dieta (incluidas las de muy bajo contenido calórico) tienen sobre el peso corporal a medio y largo plazo, poniendo de relieve que, posiblemente, los planteamientos terapéuticos de pérdida de peso deban ser diferentes de aquellos dirigidos al mantenimiento del peso perdido. Por último, cualquiera que sea el planteamiento dietético de la obesidad, no cabe duda de que el refuerzo a través de un programa estructurado de cambios en el estilo de vida y de actividad física constituye una herramienta esencial para asegurar un éxito a largo plazo.

Palabras clave:
Dieta baja en grasa
Dieta baja en hidratos de carbono
Dieta hipocalórica
Obesidad
Índice glucémico
Dieta cetogénica
Dieta de muy bajo contenido calórico
Lipoproteínas
Densidad energética
Abstract

The mainstay of the therapeutic approach to obesity is the low calorie diet. In most controlled studies the distribution of micronutrients in the diet does not seem to influence weight loss. Thus, for example, low carbohydrate diets achieve significant weight loss compared with low-fat diets in short periods (6 months), but there are no differences after longer follow-up (12 months). There is general consensus that a reduction of between 500 and 1,000 kcal daily with respect to the normal diet achieves an average weight loss of 0.5 to 1 kg per week for the first 6 months of treatment, representing a reduction of 5-10% of body weight, a proportion that is sufficient to attenuate the impact of obesity-related comorbidities. However the long-term results (more than 1 year) with low-fat diets are discouraging (0-3 kg), while the safety of low carbohydrate diets remains to be demonstrated. The present review analyzes the levels of evidence for the effect of distinct types of diet (including very low calorie diets) on body weight in the medium and long term, highlighting that possibly the therapeutic approaches to weight loss should differ from the strategies used to maintain weight loss. Lastly, whatever the dietary approach to obesity, there is no doubt that reinforcement through a structured program of lifestyle changes and physical activity is an essential tool to ensure longterm success.

Keywords:
Low-fat diet
Low carbohydrate diet
Low calorie diet
Very low calorie diet
Lipoproteins
Energy density
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Bibliografía
[1.]
N. Finner.
Low-calorie diets and sustained weight loss.
Obes Res, 9 (2001), pp. 290-294
[2.]
National Heart Lung and Blood Institute.
Obesity Education Initiative Expert Panel on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: the evidence report.
Obes Res, 6 (1998), pp. 51S-210S
[3.]
G.A. Bray, B.M. Popkin.
Dietary fat intake does affect obesity!.
Am J Clin Nutr, 68 (1998), pp. 1157-1173
[4.]
S. Yu-Poth, G. Zhao, T. Etherton, M. Naglak, S. Jonnalagadda, P.M. Kris-Etherton.
Effects of the National Cholesterol Education Program's Step and Step II dietary intervention programs on cardiovascular disease risk factors: a meta-analysis.
Am J Clin Nutr, 69 (1999), pp. 632-646
[5.]
A. Astrup, G.K. Grunwald, E.L. Melanson, W.HM. Saris, J.O. Hill.
The role of low-fat diets in body weight control: a meta-analysis of ad libitum intervention studies.
Int J Obes, 24 (2000), pp. 1545-1552
[6.]
National Diet-Heart Study Research Group.
National Diet-Heart Study Final Report.
Circulation, 37 (1968), pp. 1-428
[7.]
L. Sheppard, A.R. Kristal, L.H. Kushi.
Weight loss in women participating in a randomized trial of low-fat diets.
Am J Clin Nutr, 54 (1991), pp. 821-828
[8.]
S.E. Kasim, S. Martino, P.N. Kim, S. Khilnani, A. Boomer, J. Depper, et al.
Dietary and anthropometric determinants of plasma lipoproteins during a long-term low-fat diet in healthy women.
Am J Clin Nutr, 57 (1993), pp. 146-153
[9.]
S. Pirozzo, C. Summerbell, C. Cameron, P. Glasziou.
Should we recommend low-fat diets for obesity?.
Obes Rev, 4 (2003), pp. 83-90
[10.]
K. McManus, L. Antinoro, F. Sacks.
A randomized controlled trial of a moderate-fat, low-energy diet for weight loss in overweight adults.
Int J Obesity, 25 (2001), pp. 1503-1511
[11.]
R.W. Jeffery, W.L. Hellerstedt, S.A. French, J.E. Baxter.
A randomized trial of counseling for fat restriction versus calorie restriction in the treatment of obesity.
Int J Obesity, 19 (1995), pp. 132-137
[12.]
J.J. Powell, L. Tucker, A.G. Fisher, K. Wilcox.
The effects of different percentages of dietary fat intake, exercise, and calorie restriction on body composition and body weight in obese females.
Am J Health Promot, 8 (1994), pp. 442-448
[13.]
K. McTigue, R. Harris, B. Hemphill, L. Lux, S. Sutton, A.J. Bunton, et al.
Screening and intervention for obesity in adults: summary of the evidence for the US Preventive Task Force.
Ann Intern Med, 139 (2003), pp. 933-949
[14.]
J.W. Anderson, F.C. Konz, R.C. Frederich, C.L. Wood.
Long-term weightloss maintenance: a meta-analysis of US studies.
Am J Clin Nutr, 74 (2001), pp. 579-584
[15.]
C. Ayyad, T. Andersen.
Long-term efficacy of diet.
Obes Rev, 1 (2000), pp. 113-119
[16.]
M.B. Katan, S.M. Grundy, W.C. Willet.
Beyond low fats diets.
N Engl J Med, 337 (1997), pp. 563-566
[17.]
W.C. Willet.
Is dietary fat a major determinant of body fat.
Am J Clin Nutr, 67 (1998), pp. S556-S562
[18.]
W.C. Willet, R.L. Leibel.
Dietary fat is not a determinant of body fat.
Am J Med, 113 (2002), pp. 47S-59S
[19.]
M.L. Klem, R.R. Wing, M.T. McGuire, H.M. Seagle, J.O. Hill.
A descriptive study of individuals successful at long-term maintenance of substantial weight loss.
Am J Clin Nutr, 66 (1997), pp. 239-246
[20.]
M.T. McGuire, R.R. Wing, M.L. Klem, et al.
Behavioral strategies of individuals who have maintained long-term weight losses.
Obes Res, 7 (1999), pp. 334-341
[21.]
R.H. Knopp, C.E. Walden, B.M. Retzlaff, B.S. McCann, A.A. Dowdy, J.J. Albers, et al.
Long-term cholesterol-lowering effects of 4 fat-restricted diets in hypercholesterolemic and combined hyperlipidemic men: the Dietary Alternatives Study.
JAMA, 278 (1997), pp. 1509-1515
[22.]
D.S. Ludwig.
The Glycemic Index. Physiological mechanisms relating to obesity, diabetes and cardiovascular disease.
JAMA, 287 (2002), pp. 2414-2423
[23.]
S. Liu, W.C. Willet, M.J. Stampfer, F.B. Hu, M. Franz, L. Sampson, et al.
A prospective study of dietary glycemic load, carbohydrate intake, and risk of coronary disease in US women.
Am J Clin Nutr, 71 (2000), pp. 1455-1461
[24.]
S. Liu, J.E. Manson, J.E. Buring, M.J. Stampfer, W.C. Willet, P.M. Ridker.
Relation between a diet with a high glycemic load and plasma concentrations of high-sensitivity C-reactive protein in middle-aged women.
Am J Clin Nutr, 75 (2002), pp. 492-498
[25.]
S. Liu, W.C. Willet.
Dietary glycemic load and atherothrombotic risk.
Curr Atheroscler Rep, 4 (2002), pp. 454-461
[26.]
B. Vessby, M. Uusitupa, K. Hermansen.
Substituting dietary saturated fat for monounsaturated fat impairs insulin sensitivity in healthy men and women.
Diabetologia, 44 (2001), pp. 312-319
[27.]
F. Pérez-Jiménez, J. López-Miranda, M.D. Pinillos, et al.
A Mediterranean and a high-carbohydrate diet improve glucose metabolism in healthy young persons.
Diabetologia, 44 (2001), pp. 2038-2043
[28.]
F. Fuentes, J. López-Miranda, E. Sánchez, F. Sánchez, J. Páez, P. Rojas, et al.
Mediterranean and low-fat diets improve endothelial function in hypercholesterolemic men.
Ann Intern Med, 134 (2001), pp. 1115-1119
[29.]
K. Esposito, R. Marfella, M. Ciotola, et al.
Effect of a Mediterranan-style diet on endothelial dysfuntion and markers of vascular inflammation in the metabolic syndrome.
JAMA, 292 (2004), pp. 1440-1446
[30.]
G. Riccardi, R. Giaccob, A.A. Rivellese.
Dietary fat, insulin sensitivity and the metabolic syndrome.
Clin Nutr, 23 (2004), pp. 447-456
[31.]
Rubio MA, Ballesteros MD, Moreno C. Tratamiento nutricional del síndrome metabólico. Rev Esp Obes. En prensa 2005.
[32.]
F.F. Samaha, N. Iqbal, P. Seshadri, K.L. Chicano, D.A. Daily, J. McGrory, et al.
A low-carbohydrate as compared with a low-fat diet in severe obesity.
N Engl J Med, 348 (2003), pp. 2074-2081
[33.]
G.D. Foster, H.R. Wyatt, J.O. Hill, B.G. McGuckin, C. Brill, B.S. Mohammed, et al.
A randomized trial of low-carbohydrate diet for obesity.
N Engl J Med, 348 (2003), pp. 2082-2090
[34.]
B.J. Brehm, R.J. Seeley, S.R. Daniels, D.A. D’Alessio.
A randomized trial comparing a very low carbohydrate diet and a calorie-restricted low fat diet on body weight and cardiovascular risk factors in healthy women.
J Clin Endocrinol Metab, 88 (2003), pp. 1617-1623
[35.]
W.S. Yancy, M.K. Olsen, J.R. Guyton, R.P. Bakst, E.C. Westman.
A low-carbohydrate, ketogenic diet versus a low-fat diet to treat obesity and hyperlipidemia.
Ann Intern Med, 140 (2004), pp. 769-777
[36.]
L. Stern, N. Iqbal, P. Seshadri, K.L. Chicano, D.A. Daily, J. McGrory, et al.
The effects of low-carbohydrate versus convencional weight loss in severely obese adults: one-year follow-up of a andomized trial.
Ann Intern Med, 140 (2004), pp. 778-785
[37.]
A. Astrup.
Atkins and other low carbohydrates diets: hoax or an effective tool for weight loss?.
[38.]
K.J. Nadeau, H.R. Wyattb, J.O. Hill.
Should low-carbohydrate diets be recommended for weight loss?.
Curr Opin Endocrinol Diabetes, 11 (2004), pp. 65-69
[39.]
M.R. Freedman, J. King, E. Kennedy.
Popular diets: a scientific review.
Obes Res, 9 (2001), pp. 1S-40S
[40.]
K.J. Acheson.
Carbohydrate and weight control: where do we stand?.
Curr Opin Clin Nutr Metab Care, 7 (2004), pp. 485-492
[41.]
D.K. Layman, R.A. Boileau, D.J. Erickson, J.E. Painter, H. Shiue, C. Sather, et al.
A reduced ratio of dietary carbohydrate to protein improves body composition and blood lipid profiles during weight loss in adult women.
J Nutr, 133 (2003), pp. 411-417
[42.]
D.K. Layman, H. Shiue, C. Sather, D.J. Erickson, J. Baum.
Increased dietary protein modifies glucose and insulin homeostasis in adult women during weight loss.
J Nutr, 133 (2003), pp. 405-410
[43.]
A.R. Skov, S. Toubro, B. Ronn, L. Holm, A. Astrup.
Randomized trial on protein vs carbohydrate in ad libitum fat reduced diet for the treatment of obesity.
Int J Obes Relat Metab Disord, 23 (1999), pp. 528-536
[44.]
E. Farnsworth, N.D. Luscombe, M. Noakes, G. Wittert, E. Argyiou, P.M. Clifton.
Effect of a high-protein, energy-restricted diet on body composition, glycemic control, and lipid concentrations in overweight and obese hyperinsulinemic men and women.
Am J Clin Nutr, 78 (2003), pp. 31-39
[45.]
P.B. Mikkelsen, S. Toubro, A. Astrup.
Effect of fat-reduced diets on 24-h energy expenditure: comparisons between animal protein, vegetable protein, and carbohydrate.
Am J Clin Nutr, 72 (2000), pp. 1135-1141
[46.]
C.S. Johnston, C.S. Day, P.D. Swan.
Postprandial thermogenesis is increased 100% on a high-protein, low-fat diet versus a high-carbohydrate, low-fat diet in healthy, young women.
J Am Coll Nutr, 21 (2002), pp. 55-57
[47.]
M.S. Westerterp-Plantenga, M.P.G.M. Lejeune, I. Nijs, M. Van Ooijen, E.M.R. Kovacs.
High protein intake sustains weight maintenance after body weight loss in humans.
Int J Obes, 28 (2004), pp. 57-64
[48.]
S.T. Reddy, C.Y. Wang, K. Sakhaee, L. Brinkley, C.Y. Pack.
Effect of low-carbohydrate high protein diets on acid-base balance, stone-forming propensity, and calcium metabolism.
Am J Kidney Dis, 40 (2002), pp. 265-274
[49.]
G.H. Anderson, S.E. Moore.
Dietary proteins in the regulation of food intake and body weight in humans.
J Nutr, 134 (2004), pp. S974-S979
[50.]
S.D. Ball, K.R. Keller, L.J. Moyer-Mileur, Y.W. Ding, D. Donaldson, W.D. Jackson.
Prolongation of satiety after low versus moderately high glycemic index meals in obese adolescents.
Pediatrics, 111 (2003), pp. 488-494
[51.]
C.B. Ebbeling, M.M. Leidig, K.B. Sinclair, J.P. Hangen, D.S. Ludwig.
A reduced-glycemic load diet in the treatment of adolescent obesity.
Arch Pediatr Adolesc Med, 157 (2003), pp. 773-779
[52.]
K.H. Duncan, J.A. Bacon, R.L. Weinsier.
The effects of high and low energy density diets on satiety, energy intake, and eating time of obese and non obese subjects.
Am J Clin Nutr, 37 (1983), pp. 763-767
[53.]
M. Yao, S.B. Roberts.
Dietary energy density and weight regulation.
Nutr Rev, 59 (2001), pp. 247-258
[54.]
P. Mustajoki, T. Pekkarinen.
Very low energy diets in the treatment of obesity.
Obes Res, 2 (2001), pp. 61-72
[55.]
G.D. Foster, T.A. Wadden, F.J. Peterson, K.A. Letizia, S.J. Barlett, A.M. Conill.
A controlled comparison of three very-low calorie-diets: effects on weight, body composition, and symptoms.
Am J Clin Nutr, 55 (1992), pp. 811-817
[56.]
S. Rössner, H. Flaten.
VLCD versus LCD in long-term treatment of obesity.
Int J Obes, 21 (1997), pp. 22-26
[57.]
J.S. Torgerson, L. Agren, L. Sjöström.
Effects on body weight of strict or liberal adherence to an initial period of VLED treatment. A randomised, one year clinical trial of obese subjects.
Int J Obes, 23 (1999), pp. 190-197
[58.]
S. Rössner.
Intermittent vs. continuous VLCD therapy in obesity treatment.
Int J Obes, 22 (1998), pp. 190-192
[59.]
J.W. Anderson, S. Vichitbandra, W. Qian, R.J. Krysico.
Long-term weight management alter an intensive weight-programs.
Am J Coll Nutr, 18 (1999), pp. 620-627
[60.]
T.A. Wadden, D.L. Frey.
A multicenter evaluation of a proprietary weight loss program for the treatment of marked obesity: a five-year follow-up.
Int J Eat Disord, 22 (1997), pp. 203-212
[61.]
X. Pi-Sunyer.
The role of very-low-calorie diets in obesity.
Am J Clin Nutr, 56 (1992), pp. S240-S243
[62.]
S.B. Heymsfield, C.A.J. Van Mierlo, H.C.M. Van der Knaap, M. Heo, H.I. Frier.
Weight management using a meal replacement strategy: meta and pooling analysis from six studies.
Int J Obes, 27 (2003), pp. 537-549
[63.]
D. Quin Rothacker.
Five-year self-managemet of weight using meal replacements:comparison with matched controls in rural Wisconsin.
Nutrition, 16 (2000), pp. 344-348
[64.]
M. Fletchtner-Mors, H. Ditschuneit, T.D. Johnson, M.A. Suchard, G. Adler.
Metabolic and weight loss effects of long-term dietary intervention in obese patients: four-year results.
Obes Res, 256 (2000), pp. 2119-2125
[65.]
J.I. Álvarez-Leite.
Nutrient deficiencies secondary to bariatric surgery.
Curr Opin Clin Nutr Metab Care, 7 (2004), pp. 569-575
[66.]
L. Cabrerizo, M.A. Rubio, S. Romeo, E. Aparicio, M. Moreira.
Comparison between high protein liquid formula and a conventional hypocaloric diet after vertical banded gastroplasty: effects on body composition and energy metabolism.
Int J Obes, 23 (1999), pp. 65.
[67.]
D.D. Hensrud.
Diet and obesity.
Curr Opin Gastroenterol, 20 (2004), pp. 119-124
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