Statistics

 array:21 [
  "pii" => "S2173509314700698"
  "issn" => "21735093"
  "doi" => "10.1016/S2173-5093(14)70069-8"
  "estado" => "S300"
  "fechaPublicacion" => "2014-09-01"
  "aid" => "70069"
  "copyright" => "Sociedad Española de Endocrinología y Nutrición"
  "copyrightAnyo" => "2014"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Endocrinol Nutr. 2014;61 Supl 1:1-34"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 2165
    "formatos" => array:3 [
      "EPUB" => 6
      "HTML" => 1165
      "PDF" => 994
    ]
  ]
  "en" => array:11 [
    "idiomaDefecto" => true
    "titulo" => "Guidelines for diagnosis and treatment of adrenal insufficiency in adults"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "1"
        "paginaFinal" => "34"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Paz de Miguel Novoa, Elena Torres Vela, Nuria Palacios García, Manuela Moreira Rodríguez, Icíar Solache Guerras, María de los Ángeles Martínez de Salinas Santamaría, Anna Aulinas Masó"
        "autores" => array:8 [
          0 => array:4 [
            "nombre" => "Paz de"
            "apellidos" => "Miguel Novoa"
            "email" => array:1 [
              0 => "pazdemiguel@telefonica.net"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Elena Torres"
            "apellidos" => "Vela"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Nuria Palacios"
            "apellidos" => "Garc&#237;a"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Manuela Moreira"
            "apellidos" => "Rodr&#237;guez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Ic&#237;ar Solache"
            "apellidos" => "Guerras"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">e</span>"
                "identificador" => "aff0025"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Mar&#237;a de los"
            "apellidos" => "&#193;ngeles Mart&#237;nez de Salinas Santamar&#237;a"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">f</span>"
                "identificador" => "aff0030"
              ]
            ]
          ]
          6 => array:3 [
            "nombre" => "Anna Aulinas"
            "apellidos" => "Mas&#243;"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">g</span>"
                "identificador" => "aff0035"
              ]
            ]
          ]
          7 => array:1 [
            "colaborador" => "representing Knowledge Area Group of Neuroendocrine&#44; SEEN &#40;Grupo Insuficiencia Adrenal&#41;"
          ]
        ]
        "afiliaciones" => array:7 [
          0 => array:3 [
            "entidad" => "Department of Endocrinology and Nutrition&#44; Hospital Cl&#237;nico de San Carlos&#44; Madrid"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Department of Endocrinology and Nutrition&#44; Hospital Universitario San Cecilio&#44; Granada"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Department of Endocrinology and Nutrition&#44; Hospital Universitario Puerta de Hierro&#44; Majadahonda&#44; Madrid"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Department of Endocrinology and Nutrition&#44; Complejo Asistencial Universitario de Palencia"
            "etiqueta" => "d"
            "identificador" => "aff0020"
          ]
          4 => array:3 [
            "entidad" => "Department of Endocrinology and Nutrition&#44; Complexo Hospitalario Universitario de Ourense"
            "etiqueta" => "e"
            "identificador" => "aff0025"
          ]
          5 => array:3 [
            "entidad" => "Department of Endocrinology and Nutrition&#44; Hospital San Pedro&#44; Logro&#241;o"
            "etiqueta" => "f"
            "identificador" => "aff0030"
          ]
          6 => array:3 [
            "entidad" => "Department of Endocrinology and Nutrition&#44; Hospital de Sant Pau&#44; Barcelona"
            "etiqueta" => "g"
            "identificador" => "aff0035"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#42;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Gu&#237;a para el diagn&#243;stico y tratamiento de la insuficiencia suprarrenal en el adulto"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec340884"
          "palabras" => array:3 [
            0 => "Adrenal insufficiency"
            1 => "Diagnosis"
            2 => "Treatment"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec340883"
          "palabras" => array:3 [
            0 => "Insuficiencia adrenal"
            1 => "Diagn&#243;stico"
            2 => "Tratamiento"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Adrenal insufficiency &#40;AI&#41; is a disease characterized by a deficient production or action of glucocorticoids&#44; with or without deficiency in mineralcorticoids and&#47;or adrenal androgens&#46; It can result from disease intrinsic to the adrenal cortex &#40;primary AI&#41;&#44; from pituitary diseases that hamper the release of corticotropin &#40;secondary AI&#41; or from hypothalamic disorders that impair the secretion of the corticotropin releasing hormone &#40;tertiary AI&#41;&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">It is a disease with a low prevalence but its impact on the affected individual is very high as it can be life threathening if not treated or lead to health problems if inadequately treated&#46; However&#44; currently there are no specific guidelines for the management of this disease&#46; Therefore&#44; at the proposal of the Spanish Society of Endocrinology and Nutrition &#40;SEEN&#41; board&#44; a task force under the Neuroendocrinology Knowledge Area of the SEEN was established&#44; with the mandate of updating the diagnosis and treatment of AI&#46; In fulfilment of this mandate the task force has elaborated the present guide&#44; that&#44; based on a comprehensive review of literature&#44; is intended to provide an answer to questions related to the management of this disease&#46; It is&#44; therefore&#44; an essentially practical document&#44; mainly aimed at guiding the health professionals involved in the care of IA patients&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">La insuficiencia suprarrenal &#40;IA&#41; es un trastorno que se caracteriza por un d&#233;ficit de GC&#44; al que se asocia en ocasiones un d&#233;ficit de mineralocorticoides y&#47;o andr&#243;genos adrenales&#46; Puede ser consecuencia de enfermedades intr&#237;nsecas del c&#243;rtex adrenal &#40;IA primaria&#41;&#44; de procesos hipofisarios que afecten a la secreci&#243;n de corticotropina &#40;IA secundaria&#41; o de trastornos hipotal&#225;micos que afecten la secreci&#243;n de la hormona liberadora de corticotropina &#40;IA terciaria&#41;&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Se trata de una entidad de baja prevalencia pero con elevado impacto sobre la salud individual&#44; dado que entra&#241;a riesgo vital en ausencia de tratamiento y efectos delet&#233;reos para la salud en caso de tratamiento inadecuado&#46; En la actualidad no hay ninguna gu&#237;a de pr&#225;ctica cl&#237;nica para el manejo de esta enfermedad&#44; por este motivo&#44; a partir de una propuesta de la junta directiva de la Sociedad Espa&#241;ola de Endocrinolog&#237;a y Nutrici&#243;n &#40;SEEN&#41;&#44; se constituy&#243; un grupo de trabajo dependiente del &#193;rea de Conocimiento de Neuroendocrinolog&#237;a de la SEEN&#44; al que se encomend&#243; la tarea de actualizar el diagn&#243;stico y tratamiento de la IA del adulto&#46; En cumplimiento de esta labor&#44; el grupo de trabajo ha elaborado la presente gu&#237;a&#44; que&#44; bas&#225;ndose en una revisi&#243;n exhaustiva de la bibliograf&#237;a&#44; pretende dar respuesta a los interrogantes que se platean en el manejo de esta enfermedad&#46; Se trata&#44; por tanto&#44; de un documento de car&#225;cter eminentemente pr&#225;ctico&#44; cuya intenci&#243;n principal es servir de gu&#237;a a los profesionales que se dedican al cuidado de los pacientes con IA&#46;</p>"
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735093/00000061000000S1/v1_201408141151/S2173509314700698/v1_201408141151/en/main.assets"
  "Apartado" => null
  "PDF" => "https://static.elsevier.es/multimedia/21735093/00000061000000S1/v1_201408141151/S2173509314700698/v1_201408141151/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173509314700698?idApp=UINPBA00004N"
]