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Resumen
Staphylococcus aureus, agente causal más frecuente de las infecciones de piel y tejidos blandos (IPTB), ha experimentado en los últimos años un aumento de la resistencia a meticilina y un descenso de la sensibilidad a vancomicina. Daptomicina, por su espectro y actividad microbiológica, farmacocinética, experiencia clinica y seguridad parece un antibiótico muy apropiado en el tratamiento de las IPTB, sobre todo en las producidas por S. aureus resistente a meticilina.
Palabras clave:
Daptomicina
Staphylococcus aureus
Infección de piel y tejidos blandos
Abstract
In recent years, Staphylococcus aureus, the most commonly identified infectious agent causing skin and soft tissue infections (SSTIs), has shown an increase in methicillin resistance and decreased susceptibility to vancomycin. Because of its spectrum, microbiological activity, pharmacokinetics, and safety, as well as clinical experience in its use, daptomycin seems to be a highly appropriate antibiotic in the treatment of SSTIs, especially those produced by methicillin-resistant S. aureus.
Keywords:
Daptomycin
Staphylococcus aureus
Skin and soft tissue infections
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