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Inicio Enfermedades Infecciosas y Microbiología Clínica Update on bacteraemia in oncology and hematology
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Vol. 29. Issue S4.
Update on infectious diseases
Pages 48-53 (March 2011)
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Vol. 29. Issue S4.
Update on infectious diseases
Pages 48-53 (March 2011)
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Update on bacteraemia in oncology and hematology
Actualización en bacteriemia en oncohematología
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2868
Jesús Fortúna,
Corresponding author
fortun@ono.com

Correspondence author.
, Miguel Ángel Sanzb, Luis Maderoc, Javier Lópezd, Julián de la Torree, Isidro Jarqueb, Carlos Vallejof
a Servicio de Enfermedades Infecciosas, Hospital Ramón y Cajal, Madrid, Spain
b Servicio de Hematología, Hospital la Fe, Valencia, Spain
c Servicio de Pediatría, Hospital Niño Jesús, Madrid, Spain
d Servicio de Hematología, Hospital Ramón y Cajal, Madrid, Spain
e Servicio de Enfermedades Infecciosas, Hospital Reina Sofía, Córdoba, Spain
f Servicio de Hematología, Hospital Universitario, Murcia, Spain
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Abstract

The present article is an update of the literature on bacteraemia in onco-hematologic patients. A multidisciplinary group of Spanish physicians with an interest in this field selected the most important papers published recently. Papers from the fields of basic science, epidemiology, causative microorganisms and clinical syndromes are discussed. Important aspects of these studies include the assessment of different strategies in the management of fever in neutropenic patients and the validation of specific scores. Moreover, early identification of patients at risk of bacterial and of multi-drug resistant infections is a topic of increasing interest.

Keywords:
Bacteraemia
Hematology
Oncology
Update
Review
Resumen

El trabajo que se presenta es una revisión de la bibliografía reciente más relevante publicada en relación con la bacteriemia en pacientes oncohematológicos. Un grupo multidisciplinar compuesto por diferentes especialistas españoles con interés en este campo revisa los artículos más notables. Los trabajos pertenecen a áreas de investigación básica, epidemiología, agentes causales y síndromes clínicos. Se analizan diferentes aspectos, incluyendo estrategias del manejo de la fiebre en el paciente neutropénico y la validación de scores específicos. La identificación precoz de factores de riesgo de infección bacteriana y de infección por microorganismos multirresistentes es objetivo de especial interés.

Palabras clave:
Bacteriemia
Hematología
Oncología
Actualización
Revisión
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References
[1.]
C. Viscoli, E. Castagnola.
Prophylaxis and empirical therapy of infection in cancer patients.
Principles and practice of infectious diseases, 7th ed., pp. 3793-3807
[2.]
E. Castagnola, M. Faraci.
Management of bacteremia in patients undergoing hematopoietic stem cell transplantation.
Expert Rev Anti Infect Ther, 7 (2009), pp. 607-621
[3.]
M. Vekemans, J. Robinson, A. Georgala, C. Heymans, F. Muanza, M. Paesmans, et al.
Low mannose-binding lectin concentration is associated with severe infection in patients with hematological cancer who are undergoing chemotherapy.
Clin Infect Dis, 44 (2007), pp. 1593-1601
[4.]
J. Ramzi, Z. Mohamed, B. Yosr, K. Karima, B. Raihane, A. Lamia, et al.
Predictive factors of septic shock and mortality in neutropenic patients.
Hematology, 12 (2007), pp. 543-548
[5.]
M. Tumbarello, T. Spanu, M. Caira, E.M. Trecarichi, L. Laurenti, E. Montuori, et al.
Factors associated with mortality in bacteremic patients with hematologic malignancies.
Diagn Microbiol Infect Dis, 64 (2009), pp. 320-326
[6.]
M.W. Richardson, S.S. Grewal, P.F. Visintainer.
Emesis predicts bacteremia in immunocompromised children with central venous catheters and fever.
Cancer, 115 (2009), pp. 3335-3340
[7.]
H.R. Paganini, C. Aguirre, G. Puppa, C. Garbini, R.G. Javier, G. Ensinck, et al.
A prospective, multicentric scoring system to predict mortality in febrile neutropenic children with cancer.
Cancer, 109 (2007), pp. 2572-2579
[8.]
M. Craig, A.D. Cumpston, G.R. Hobbs, M.P. Devetten, A.R. Sarwari, S.G. Ericson.
The clinical impact of antibacterial prophylaxis and cycling antibiotics for febrile neutropenia in a hematological malignancy and transplantation unit.
Bone Marrow Transplant, 39 (2007), pp. 477-482
[9.]
G. Rangaraj, B.P. Granwehr, Y. Jiang, R. Hachem, I. Raad.
Perils of quinolone exposure in cancer patients: breakthrough bacteremia with multidrug-resistant organisms.
Cancer, 116 (2010), pp. 967-973
[10.]
G. Ghanem, R. Hachem, Y. Jiang, R.F. Chemaly, I. Raad.
Outcomes for and risk factors associated with vancomycin-resistant Enterococcus faecalis and vancomycin-resistant Enterococcus faecium bacteremia in cancer patients.
Infect Control Hosp Epidemiol, 28 (2007), pp. 1054-1059
[11.]
L.J. Worth, K.A. Thursky, J.F. Seymour, M.A. Slavin.
Vancomycin-resistant Enterococcus faecium infection in patients with hematologic malignancy: patients with acute myeloid leukemia are at high-risk.
European J Haematol, 79 (2007), pp. 226-233
[12.]
D.D. Poutsiaka, S. Skiffington, K.B. Miller, S. Hadley, D.R. Snydman.
Daptomycin in the treatment of vancomycin-resistant Enterococcus faecium bacteremia in neutropenic patients.
J Infect, 54 (2007), pp. 567-571
[13.]
S. Youssef, G. Rodríguez, K.V. Rolston, R.E. Champlin, I.I. Raad, A. Safdar.
Streptococcus pneumoniae infections in 47 hematopoietic stem cell transplantation recipients: clinical characteristics of infections and vaccine-breakthrough infections, 1989–2005.
Medicine (Baltimore), 86 (2007), pp. 69-77
[14.]
R. Meisel, A.M. Toschke, C. Heiligensetzer, D. Dilloo, H.J. Laws, R. Von Kries.
Increased risk for invasive pneumococcal diseases in children with acute lymphoblastic leukaemia.
British J Haematol, 137 (2007), pp. 457-460
[15.]
A. Moreno, C. Cervera, J. Gavaldà, M. Rovira, R. De la Camara, I. Jarque, et al.
Bloodstream infections among transplant recipients: results of a nationwide surveillance in Spain.
Am J Transplant, 7 (2007), pp. 2579-2586
[16.]
E.M. Trecarichi, M. Tumbarello, T. Spanu, M. Caira, L. Fianchi, P. Chiusolo, et al.
Incidence and clinical impact of extended-spectrum-beta-lactamase (ESBL) production and fluoroquinolone resistance in bloodstream infections caused by Escherichia coli in patients with hematological malignancies.
J Infect, 58 (2009), pp. 299-307
[17.]
E. Castagnola, V. Fontana, I. Caviglia, S. Caruso, M. Faraci, F. Fioredda, et al.
A prospective study on the epidemiology of febrile episodes during chemotherapy-induced neutropenia in children with cancer or after hemopoietic stem cell transplantation.
Clin Infect Dis, 45 (2007), pp. 1296-1304
[18.]
N. Puig, J. De la Rubia, I. Jarque, M. Salavert, P. Montesinos, J. Sanz, et al.
A study of incidence and characteristics of infections in 476 patients from a single center undergoing autologous blood stem cell transplantation.
Int J Haematol, 86 (2007), pp. 186-192
[19.]
A. Tomonari, S. Takahashi, J. Ooi, N. Tsukada, T. Konuma, T. Kobayashi, et al.
Bacterial bloodstream infection in neutropenic adult patients after myeloablative cord blood transplantation: experience of a single institution in Japan.
Int J Haematol, 85 (2007), pp. 238-241
[20.]
I. Raad, R. Hachem, H. Hanna, P. Bahna, I. Chatzinikolaou, X. Fang, et al.
Sources and outcome of bloodstream infections in cancer patients: the role of central venous catheters.
Eur J Clin Microbiol Infect Dis, 26 (2007), pp. 549-556
[21.]
M. Hummel, C. Warga, H. Hof, R. Hehlmann, D. Buchheidt.
Diagnostic yield of blood cultures from antibiotic-naive and antibiotically treated patients with haematological malignancies and high-risk neutropenia.
Scand J Infect Dis, 41 (2009), pp. 650-655
Copyright © 2011. Elsevier España S.L.. All rights reserved
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