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The impact of anxiety and depression on quality of life in a cohort of inflammatory bowel disease patients from northeastern of brazil
El impacto de la ansiedad y la depresión en la calidad de vida en una cohorte de pacientes con enfermedad inflamatoria intestinal en el nordeste de brasil.
Raiza Lima Silva1, Francisca Isabelle da Silva e Sousa1, Gabriel Lucas Ferreira da Silva1, Victória Danielly Rabelo Almeida1, Simão Barbosa Silva1, Mateus Mendes Santos Freire1, Marcellus Henrique Loiola Ponte de Souza2, Lucia Libanez Bessa Campelo Braga2,
Corresponding author
lucialib@terra.com.br

Corresponding author: Doctorate in Gastroenterology, Department of Internal Medicine - Federal University of Ceará, Prof. Costa Mendes, 1608, 4th floor - Rodolfo Teófilo, Brazil
1 School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil
2 Department of Internal Medicine, Federal University of Ceará, Walter Cantídio University Hospital, Fortaleza, CE, Brazil
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Objective&#58; This study aims to assess the association between chronic pathologies and depressive and&#47;or anxious disorders is high resulting in a reduction in the patient&#39;s quality of life&#46;</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Patients and methods&#58; This is a prospective cross-sectional study with a descriptive and analytical design&#46; Sociodemographic data and lifestyle habits were collected&#46; Subsequently&#44; the Inflammatory Bowel Disease Questionnaire &#40;IBDQ&#41; and the Hospital Anxiety and Depression Scale &#40;HADS&#41; were applied&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Results A total of 141 patients participated in the study&#44; with a mean age of 45&#46;78 &#40;SD 16&#46;01&#41; years&#44; of which 60&#46;3&#37; were female &#40;n&#61;85&#41; and 39&#46;7&#37; were male &#40;n&#61;56&#41;&#46; 58&#46;9&#37; had ulcerative colitis &#40;UC&#41; &#40;n&#61;83&#41;&#44; and 41&#46;1&#37; had Crohn&#39;s disease &#40;CD&#41; &#40;n&#61;58&#41;&#46; 16&#46;5&#37; of patients had a previous diagnosis of generalized anxiety disorder &#40;GAD&#41; and&#47;or major depression &#40;MD&#41; &#40;n&#61;23&#41;&#46; Regarding IBDQ scores&#44; participants with anxiety had significantly lower mean scores in all IBDQ items &#40;p&#60;0&#46;001&#41;&#44; while the depression diagnosis obtained significantly lower mean values for systemic &#40;p&#61;0&#46;015&#41;&#44; emotional &#40;p&#61;0&#46;001&#41;&#44; and intestinal symptoms &#40;p&#61;0&#46;005&#41;&#46;</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Conclusion The results indicate that anxiety and depression negatively impact the quality of life of patients with IBD independently of the disease activity&#46;</p></span>"
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        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Objetivo&#58; El presente estudio tiene como objetivo evaluar la asociaci&#243;n entre patolog&#237;as cr&#243;nicas y trastornos depresivos y&#47;o ansiosos es alta resultando en una reducci&#243;n de la calidad de vida del paciente&#46;</p><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Pacientes y m&#233;todos&#58; Se trata de un estudio prospectivo transversal con un dise&#241;o descriptivo y anal&#237;tico&#46; Se recogieron datos sociodemogr&#225;ficos y h&#225;bitos de vida&#46; Posteriormente&#44; se aplicaron el Cuestionario de Enfermedad Inflamatoria Intestinal &#40;IBDQ&#41; y la Escala Hospitalaria de Ansiedad y Depresi&#243;n &#40;HADS&#41;&#46;</p><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Resultados&#58; Participaron en el estudio 141 pacientes&#44; con una edad media de 45&#44;78 &#40;DE 16&#44;01&#41; a&#241;os&#44; de los cuales el 60&#44;3&#37; eran mujeres &#40;n&#61;85&#41; y el 39&#44;7&#37; varones &#40;n&#61;56&#41;&#46; La mayor&#237;a padec&#237;a colitis ulcerosa &#40;CU&#41; &#40;n&#61;83&#59; 58&#44;9&#37;&#41;&#44; y el 41&#44;1&#37; enfermedad de Crohn &#40;EC&#41; &#40;n&#61;58&#41;&#46; El 16&#44;5&#37; de los pacientes ten&#237;a un diagn&#243;stico previo de trastorno de ansiedad generalizada &#40;TAG&#41; y&#47;o depresi&#243;n mayor &#40;DM&#41; &#40;n&#61;23&#41;&#46; En cuanto a las puntuaciones del IBDQ&#44; los participantes con ansiedad presentaron puntuaciones medias significativamente inferiores en todos los &#237;tems del IBDQ &#40;p&#60;0&#44;001&#41;&#44; mientras que el diagn&#243;stico de depresi&#243;n obtuvo valores medios significativamente inferiores para los s&#237;ntomas sist&#233;micos &#40;p&#61;0&#44;015&#41;&#44; emocionales &#40;p&#61;0&#44;001&#41; e intestinales &#40;p&#61;0&#44;005&#41;&#46;</p><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Conclusi&#243;n&#58; Los resultados indican que la ansiedad y la depresi&#243;n afectan negativamente a la calidad de vida de los pacientes con EII independientemente de la actividad de la enfermedad&#46;</p></span>"
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