metricas
covid
Buscar en
Gastroenterología y Hepatología
Toda la web
Inicio Gastroenterología y Hepatología Derivación portosistémica percutánea intrahepática como tratamiento del hidr...
Journal Information
Vol. 25. Issue 3.
Pages 143-147 (January 2002)
Share
Share
Download PDF
More article options
Vol. 25. Issue 3.
Pages 143-147 (January 2002)
Full text access
Derivación portosistémica percutánea intrahepática como tratamiento del hidrotórax hepático refractario
Percutaneous intrahepatic portosystemic shunting as a treatment for refractory hepatic hydrothorax
Visits
6079
O. Núñez, A. García, D. Rincón, S. Alonso, R. Bañares
Corresponding author
banares@inicia.es

Correspondencia: Servicio de Aparato Digestivo. Hospital General Universitario Gregorio Marañón. Dr. Esquerdo, 46. 28007 Madrid.
Servicios de Aparato Digestivo. Hospital General Universitario Gregorio Marañón. Madrid
A. Echenagusía*
* Servicios de Radiología. Hospital General Universitario Gregorio Marañón. Madrid
This item has received
Article information
Resumen

El hidrotórax hepático es una complicación infrecuente de la hipertensión portal en la cirrosis hepática. El tratamiento con restricción salina y diuréticos es generalmente eficaz, pero cuando fracasa, su abordaje terapéutico es dificultoso y conlleva múltiples complicaciones. La derivación portosistémica percutánea intrahepática (DPPI) se asocia con un notable descenso de la presión portal, por lo que ha sido usada en el tratamiento de la ascitis refractaria.

El objetivo de este estudio fue analizar la eficacia, la seguridad y la evolución del hidrotórax hepático refractario (HHR) tratado mediante DPPI. El procedimiento se realizó en 5 pacientes, todos ellos de grado B o C de la clasificación de Child-Pugh. Tres de los pacientes presentaron respuesta completa al tratamiento, siendo uno de ellos trasplantado 20 días después, en otro hubo una respuesta parcial con disminución de la necesidad de realización de toracocentesis, y el quinto paciente murió a los 17 días de seguimiento sin respuesta a la DPPI. No se apreciaron modificaciones de los valores de albúmina ni del grado de Child. Dos pacientes presentaron recurrencia con reaparición del hidrotórax por disfunción de la DPPI, y otros dos presentaron encefalopatía hepática que respondió al tratamiento médico. La DPPI permite el control del hidrotórax refractario en un porcentaje elevado de casos, pero su eficacia se ve limitada por la presencia de disfunción, por el riesgo de encefalopatía y por el escaso impacto sobre la supervivencia.

Hepatic hydrothorax is an infrequent complication of portal hypertension in liver cirrhosis. Treatment with saline restriction and diuretics is usually effective but when this fails, the therapeutic approach is difficult and multiple complications occur. Transjugular percutaneous intrahepatic portosystemic shunt (IPS) is associated with a marked decrease in portal pressure and consequently this technique has been used in the treatment of refractory ascites. The aim of this study was to analyze the efficacy, safety and outcome of refractory hepatic hydrothorax treated by IPS.

The procedure was performed in 5 patients who were all grade B or C in the Child-Pugh classification. Three patients showed complete response to the treatment, of whom 1 underwent transplantation 20 days later. The fourth patient showed partial response with a reduction in the need to perform thoracocentesis and the fifth patient showed no response to IPS and died after 17 days of follow-up. Albumin levels and Child classification remained unchanged. Two patients presented recurrence with reappearance of hydrothorax due to shunt dysfunction and 2 patients presented hepatic encephalopathy that responded to medical treatment.

Refractory hepatic hydrothorax can be controlled by IPS in a large number of patients but its efficacy is restricted by shunt dysfunction, the risk of encephalopathy and by its limited effect on survival.

Full text is only aviable in PDF
Biblografía
[1.]
C.S. Morrow, M. Kantor, R.N. Armen.
Hepatic hydrothorax.
Ann Intern Med, 49 (1958), pp. 193-203
[2.]
K.N. Lazardis, J.W. Frank, M.J. Krowka, P.S. Kamath.
Hepatic hydrotorax: pathogenesis, diagnosis and management.
Am J Med, 107 (1999), pp. 262-267
[3.]
W.M. Alberts, A.J. Salem, D.A. Solomon, G. Boyce.
Hepatic hydrotorax. Cause and management.
Arch Intern Med, 151 (1991), pp. 2383-2388
[4.]
F.L. Lieberman, R. Hidemura, R.L. Peters, T.B. Reynolds.
Pathogenesis and treatment of hydrotorax complicating cirrhosis with ascites.
Ann Intern Med, 64 (1966), pp. 341-351
[5.]
R. Golpe, L. García, M.M. García, E. Sánchez, A. Jiménez.
Hidrotórax hepático sin ascitis: presentación de un caso y revisión de la literatura.
An Med Intern, 15 (1998), pp. 541-543
[6.]
S. Kakizaki, T. Yoshinaga, T. Higuchi, H. Takayama, H. Takagi, T. Nagamine, et al.
Hepatic hydrotorax in the absence of ascites.
Liver, 18 (1998), pp. 216-220
[7.]
X. Xiol, R. Cortés, J. Castellote, E. Sese, J. Guardiola, J.M. Bofargues, et al.
Utility and complications of thoracocentesis in cirrhotic patients.
Hepatology, 26 (1997), pp. A632
[8.]
J. Mouroux, C. Perrin, N. Venissac, B. Blaive, H. Richelme.
Management of pleural effusion of cirrhotic origin.
Chest, 109 (1996), pp. 1093-1095
[9.]
A. Giacobbe, D. Facciorusso, F. Barbano, A. Andriulli, V. Frusciante.
Hepatic hydrotorax. Diagnosis and management.
Clin Nucl Med, 21 (1996), pp. 56-60
[10.]
E. Ghandour, J. Carter, M. Feola, K.M. Nugent.
Management of hepatic hydrothorax with a peritoneovenous (Denver) shunt.
South Med J, 83 (1990), pp. 718-719
[11.]
V. Arroyo, A. Cárdenas.
TIPS in the treatment of refractory ascitis.
Treatment of liver diseases, pp. 43-51
[12.]
M. Rösle, A. Ochs, V. Gülberg, V. Siegerstetter, J. Holl, P. Deibert, et al.
A comparison of paracentesis and transjugular intrahepatic portosystemic shunting in patients with ascitis.
N Engl J Med, 342 (2000), pp. 1701-1707
[13.]
R.M. Strauss, L.G. Martin, S.L. Kaufman, T.D. Boyer.
Transjugular intrahepatic portal systemic shunt for the management of symptomatic cirrhotic hydrothorax.
Am J Gastroenterol, 89 (1994), pp. 1520-1522
[14.]
F.D. Gordon, H.T. Anastopoulos, W. Crenshaw, B. Gilchrist, N. McEniff, K.R. Falchuk, et al.
The succesful treatment of symptomatic, refractory hepatic hydrothorax with transjugular intrahepatic portosystemic shunt.
Hepatology, 25 (1997), pp. 1366-1369
[15.]
N. Chalasani, L.G. Martin, R.M. Strauss, T.D. Boyer.
Transjugular intrahepatic portosystemic shunt (TIPS) for refractory hepatic hydrotorax (HHRT)-Good for the lung, not so good for the liver.
Hepatology, 26 (1997), pp. A630
[16.]
M.A. Jeffries, S. Kazanjian, M. Wilson, J. Punch, R.J. Fontana.
Transjugular intrahepatic portosystemic shunts and liver transplantation in patients with refractory hepatic hydrothorax.
Liver Transplant Surg, 4 (1998), pp. 416-423
[17.]
M. Rösle, K. Haag, A. Ochs, M. Sellinger, G. Nöldge, J.M. Perarnau, et al.
The transjugular intrahepatic portosystemic stent-shunt procedure for variceal bleeding.
N Engl J Med, 330 (1994), pp. 165-171
[18.]
H.O. Conn.
Transjugular intrahepatic portal-systemic shunts: the state of the art.
Hepatology, 17 (1993), pp. 148-158
[19.]
J. Uriz, P. Ginés.
Randomized, multicenter, comparative study between TIPS and paracentesis with albumin in cirrhosis with refractory ascites [abstract].
J Hepatol, 34 (2001), pp. 10
[20.]
D. Lebrec, N. Giuily, A. Hadengue, V. Vilgram, R. Moreau, T. Poynard, et al.
Transjugular intrahepatic portocaval shunts: comparision with paracentesis in patients with cirrhosis and refractory ascites: a randomized trial.
J Hepatol, 25 (1996), pp. 135-144
[21.]
F. Wong, K. Sniderman, P. Liu, Y. Allidina, M. Sherman, L. Blendis.
Transjugular intrahepatic portosystemic stent shunt: effects on hemodynamics and sodium homeostasis in cirrhosis and refractory ascites.
Ann Intern Med, 122 (1995), pp. 816-822
[22.]
J. Quiroga, B. Sangro, M. Núñez, I. Bilbao, J. Longo, L. García-Villarreal, et al.
Transyugular portal-systemic shunt in the treatment of refractory ascites: effect on clinical, renal, humoral, and hemodynamic parameters.
Hepatology, 21 (1995), pp. 986-994
[23.]
M. Casado, J. Bosch, J. García-Pagán, C. Bru, R. Bañares, J.C. Bandi, et al.
Clinical events after transjugular intrahepatic portosystemic shunt. Correlation with hemodynamic findings.
Gastroenterology, 114 (1998), pp. 1296-1303
[24.]
M. Rössle, V. Siegerstetter, M. Huber, A. Ochs.
The first decade of the transjugular portosystemic shunt (TIPS): state of the art.
Liver, 18 (1998), pp. 73-89
[25.]
M. Guevara, P. Ginés, J.C. Bandi, R. Gilabert, P. Sort, W. Jiménez, et al.
Transjugular intrahepatic portosystemic shunt in hepatorrenal syndrome: effects on renal function and vasoactive systems.
Hepatology, 28 (1998), pp. 416-422
[26.]
K.A. Brensing, J. Textor, J. Perz, P. Schiedermaier, P. Raab, H. Strunk, et al.
Long term outcome after transjugular intrahepatic portosystemic stent-shunt in non-transplant cirrhotics with hepatorrenal syndrome: a phase II study.
Gut, 47 (2000), pp. 288-295
[27.]
N. Chalasani, W.C. Clark, L.G. Martin, J. Kamean, M.A. Khan, N.H. Patel, et al.
Determinants of mortality in patients with advanced cirrhosis after transjugular intrahepatic portosystemic shunting.
Gastroenterology, 118 (2000), pp. 138-144
[28.]
M. Malinchoc, P.S. Kamath, F.A. Gordon, C.J. Peine, J. Rank.
Ter Borg PCJ. A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts.
Hepatology, 31 (2000), pp. 864-871
[29.]
J.M. Rodríguez-Laiz, R. Bañares, A. Echenagusía, M. Casado, F. Camúnez, F. Pérez-Roldan, et al.
Effects of transjugular intrahepatic portasystemic shunt (TIPS) on splanchnic and systemic hemodynamics, and hepatic function in patients with portal hypertension. Preliminary results.
Dig Dis Sci, 40 (1995), pp. 2121-2127
Copyright © 2002. Elsevier España, S.L.. Todos los derechos reservados
Download PDF
Article options
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos