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Vol. 34. Issue S2.
Jornada de Actualización en Gastroenterología Aplicada
Pages 78-81 (October 2011)
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Vol. 34. Issue S2.
Jornada de Actualización en Gastroenterología Aplicada
Pages 78-81 (October 2011)
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Pancreatitis crónica
Chronic pancreatitis
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J. Enrique Domínguez-Muñoz
Servicio de Aparato Digestivo, Hospital Clínico Universitario de Santiago, Santiago de Compostela, España
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Resumen

El presente artículo pretende resumir los avances más relevantes con implicación clínica en pancreatitis crónica presentados en el último Congreso Americano de Gastroenterología. La ecografía endoscópica se considera el método de elección para el diagnóstico de la pancreatitis crónica. Sin embargo, nuevos estudios sugieren que la clasificación diagnóstica de Rosemont no es útil en fases tempranas de la enfermedad, mientras que otros demuestran que, en pacientes con dolor abdominal, una pancreatitis crónica puede estar presente, aunque la ecoendoscopia muestre menos de 3 criterios de la enfermedad. Por el contrario, nuevos estudios apoyan la utilidad de la ecoendoscopia en el diagnóstico de la pancreatitis autoinmunitaria en pacientes en los que se demuestra la presencia de ductitis pancreática. Desde el punto de vista terapéutico, cabe destacar la demostración en un ensayo clínico aleatorizado, controlado con placebo, de la eficacia del tratamiento con pregabalina en el dolor secundario a pancreatitis crónica.

Palabras clave:
Drenaje endoscópico
Ecografía endoscópica
Pancreatitis autoinmunitaria
Pancreatitis crónica
Pregabalina
Abstract

The present article summarizes some of the most important results with potential clinical impact on the diagnosis and management of chronic pancreatitis presented at the last meeting of Digestive Disease Week. Endoscopic ultrasound (EUS) is currently the method of choice for the diagnosis of chronic pancreatitis in clinical practice. However, some new studies suggest that the Rosemont classification is not useful for diagnosis of this disease in the early stages, whereas others show that, in patients with abdominal pain, chronic pancreatitis cannot be excluded even when there are less than three EUS criteria of the disease. In contrast, new studies support the usefulness of endoscopic ultrasound for the diagnosis of autoimmune pancreatitis in the presence of pancreatic ductitis. From the therapeutic point of view, a notable contribution at the congress was a new randomized placebo-controlled clinical trial showing the efficacy of pregabalin for the treatment of pain in chronic pancreatitis.

Keywords:
Endoscopic drainage
Endoscopic ultrasound
Autoimmune pancreatitis
Chronic pancreatitis
Pregabalin
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Bibliografía
[1.]
B. Etemad, D.C. Whitcomb.
Chronic pancreatitis: diagnosis, classification, and new genetic developments.
Gastroenterology, 120 (2001), pp. 682-707
[2.]
D. Yadav, R.H. Hawes, R.E. Brand, et al.
Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitis.
Arch Intern Med, 169 (2009), pp. 1035-1045
[3.]
M.F. Catalano, A. Sahai, M. Levy, J. Romagnuolo, M. Wiersema, W. Brugge, et al.
EUS-based criteria for the diagnosis of chronic pancreatitis: the Rosemont classification.
Gastrointest Endosc, 69 (2009), pp. 1251-1261
[4.]
C.W. Teshima, J.W. Poley, A. Koch, F. Harinck, M. Bruno.
Prospective assessment of the “Rosemont classification” criteria for the diagnosis of chronic pancreatitis by endoscopic ultrasound.
Gastrointest Endosc, 73 (2011), pp. AB332
[5.]
S. Albashir, M.P. Bronner, M.A. Parsi, R.M. Walsh, T. Stevens.
Endoscopic ultrasound, secretin endoscopic pancreatic function test, and histology: correlation in chronic pancreatitis.
Am J Gastroenterol, 105 (2010), pp. 2498-2503
[6.]
J.K. LeBlanc, J.H. Chen, J.M. DeWitt, M.A. Al-Haddad, L. McHenry, M. Symms, et al.
EUS and histopathology features in chronic pancreatitis.
Gastrointest Endosc, 73 (2011), pp. AB329-AB330
[7.]
J. Vega-Peralta, R. Attam, M.A. Arain, S. Mallery, D. Radosevich, F. Khamis, et al.
Correlation of EUS with histopathology in 50 patients undergoing total pancreatectomy (TP) with islet autotransplantion (IAT) for minimal change chronic pancreatitis (MCCP).
Gastrointest Endosc, 73 (2011), pp. AB324
[8.]
S.S. Olesen, S.A. Bouwense, O.H. Wilder-Smith, H. Van Goor, A.M. Drewes.
Pregabalin reduces pain in patients with chronic pancreatitis in a randomized, controlled trial.
Gastroenterology, 141 (2011), pp. 536-543
[9.]
D.L. Cahen, D.J. Gouma, Y. Nio, E.A. Rauws, M.A. Boermeester, O.R. Busch, et al.
Endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis.
N Engl J Med, 356 (2007), pp. 676-684
[10.]
D.L. Cahen, D.J. Gouma, P. Laramee, C.Y. Nio, E. Rauws, M.A. Boermeester, et al.
Endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis: long-term outcome.
Gastroenterology, 140 (2011), pp. S69
[11.]
B.E. Young, B.U. Wu, D.A. Klibansky, T.B. Gardner, D.M. Simeone, R.S. Kwon.
Do clinical outcomes after ERCP with pancreatic duct stenting predict clinical outcomes after lateral pancreaticojejunostomy for patients with chronic pancreatitis?.
Gastrointest Endosc, 73 (2011), pp. AB262
[12.]
M. Castiñeira-Alvariño, M. Luaces-Regueira, L. Nieto, J. Iglesias-Garcia, J. Larino-Noia, J.E. Dominguez-Munoz.
Association of fat consumption with clinical manifestations, diagnosis and severity of chronic pancreatitis.
Gastroenterology, 140 (2011), pp. S859
[13.]
J.K. Sai, M. Suyama, Y. Matsumura, Y. Takahashi, J. Maruki, S. Ishii, et al.
Efficacy of low fat diet against dyspepsia associated with non-alcoholic mild pancreatic disease.
Gastrointest Endosc, 73 (2011), pp. AB256
[14.]
S.T. Chari, T.C. Smyrk, M.J. Levy, et al.
Diagnosis of autoimmune pancreatitis: the Mayo Clinic experience.
Clin Gastroenterol Hepatol, 4 (2006), pp. 1010-1016
[15.]
M. Palazzo, L. Palazzo, A. Aubert, D. O’Toole, A. Couvelard, M. Fabre, et al.
Ductitis at endoscopic ultrasonography has high diagnosis value in autoimmune pancreatitis.
Gastroenterology, 140 (2011), pp. S545
[16.]
J. Kim, Y.T. Kim, D.W. Ahn, W.J. Yoon, J.K. Ryu, Y.B. Yoon.
The long term clinical outcome of patients without low dose steroid maintenance treatment for autoimmune pancreatitis.
Gastroenterology, 140 (2011), pp. S547-S548
Copyright © 2011. Elsevier España S.L.. Todos los derechos reservados
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