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Inicio Gastroenterología y Hepatología (English Edition) Duodenal target sign
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Vol. 44. Issue 8.
Pages 577-578 (October 2021)
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Vol. 44. Issue 8.
Pages 577-578 (October 2021)
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Duodenal target sign
Signo del blanco duodenal
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Ana Laranjo
Corresponding author
anamlaranjo@gmail.com

Corresponding author.
, Maria Carvalho, Andreia Rei, Nuno Veloso
Hospital Espírito Santo de Évora, Évora, Portugal
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A 67-year-old man with MUTYH-associated polyposis underwent an en bloc endoscopic mucosal resection (EMR) of a 20mm non-granular laterally spreading tumor, type 0-IIa of the Paris classification, in the duodenum, distally to the ampulla region (Fig. 1).

Figure 1.

Upper endoscopic image revealing a non-granular laterally spreading tumor in the duodenum.

(0.09MB).

After resection, a “target sign” was observed (Figs. 2 and 3). The defect was closed by endoscopic clipping using five clips in a zipper fashion and a nasojejunal feeding tube was placed distally to the EMR region.

Figure 2.

Endoscopic image showing the “target sign”.

(0.09MB).
Figure 3.

Inadvertently resected muscularis propria creating the “target sign”.

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Postprocedure abdominal CT with contrast showed a thin layer of retroperitoneal free air, but no contrast extravasation was observed. The patient was managed conservatively and discharged four days later, completely asymptomatic.

EMR for the duodenum carries a high risk of perforation, due to the thin muscle layer in this region, compared with the remaining digestive tract. Generally, the risk for perforation is higher in large lesions (>20mm)1. Early diagnosis of perforation can be made by careful analysis of the post-EMR specimen which may reveal a “target sign”, a marker of resection of the muscularis propria and imminent perforation. Colonic target sign is common, but it is rare in the duodenum2.

Recognition of this sign allows endoscopic management instead of surgery, with a shorter hospital stay and fewer adverse events.

Conflict of interests

None of the authors has any financial/conflicting interests to disclose.

References
[1]
Y. Ochiai, M. Kato, Y. Kiguchi, T. Akimoto, A. Nakayama, M. Sasaki, et al.
Current status and challenges of endoscopic treatments for duodenal tumors.
Digestion, 99 (2019), pp. 21-26
[2]
M.P. Swan, M.J. Bourke, A. Moss, S.J. Williams, A. Hopper, A. Metz.
The target sign: an endoscopic marker for the resection of the muscularis propria and potential perforation during colonic endoscopic mucosal resection.
Gastrointest Endosc, 73 (2011), pp. 79-85
Copyright © 2020. Elsevier España, S.L.U.. All rights reserved
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