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Inicio Hipertensión y Riesgo Vascular Derrame pericárdico crónico atribuible a minoxidil
Journal Information
Vol. 22. Issue 4.
Pages 183-185 (May 2005)
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Vol. 22. Issue 4.
Pages 183-185 (May 2005)
Derrame pericárdico crónico atribuible a minoxidil
Chronic pericardial effusion attributable to minoxidil
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4167
F. Maroto Monserrataa,
Corresponding author
fernando_maroto8@hotmail.com

Correspondencia: Plaza de Cuba, 9, 1.º A. 41011 Sevilla. España.
, C. Camacho Vázquezbb, S. Benito Conejerocc
a Servicios de Medicina Intensiva. Hospital Juan Ramón Jiménez. Huelva. España
b Cardiología. Hospital Juan Ramón Jiménez. Huelva. España
c Medicina Interna. Hospital Juan Ramón Jiménez. Huelva. España
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El minoxidil es un potente vasodilatador oral que era frecuentemente utilizado en hipertensión arterial refractaria a tratamiento con otros fármacos, cuya relación con la aparición de derrame pericárdico se conoce prácticamente desde el comienzo de su uso clínico. Describimos un caso de derrame pericárdico grave asociado a la toma de minoxidil durante más de 20 años que responde favorablemente a la retirada del fármaco a pesar de tan larga evolución.La incidencia descrita de derrame pericárdico por minoxidil se encuentra entre un 0 %–26 % y, a pesar de la posible evolución hacia taponamiento cardíaco en raros casos, el manejo conservador con la retirada del fármaco es la primera opción, que en nuestra opinión debe serlo incluso cuando el derrame sea grave y de muy larga evolución.

Palabras clave:
minoxidil
derrame pericárdico
grave
crónico
conservador

Minoxidil is a potent oral vasodilator that was frequently used in HBP refractory to treatment with other drugs, whose relationship with the appearance of pericardial effusion has practically been known since the onset of its clinical use. We describe a case of severe pericardial effusion, associated to taking minoxidil for more than 20 years that favorably responds to withdrawal of the drug in spite of such a long course. The incidence described of pericardial effusion due to minoxidil is between 0 %-26 %. In spite of the possible evolution towards cardiac tamponade in rare cases, the conservative management with drug withdrawal is the first option, which, in our opinion, should even be so when the effusion is severe and of long duration.

Key words:
minoxidil
pericardial effusion
severe
chronic
conservative

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