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Vol. 14. Issue 1.
Pages 47-54 (March 2010)
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Vol. 14. Issue 1.
Pages 47-54 (March 2010)
Open Access
Tuberculosis pleural asociada con adalimumab, en un paciente con artritis reumatoide
Pleural tuberculosis associated with adalimumab in a patient with rheumatoid arthritis
Visits
2125
Patricia Hidalgo1,
Corresponding author
hidalgop@javeriana.edu.co

Unidad de Neumología, Hospital Universitario San Ignacio. Carrera 7 N° 40-62, Bogotá, D.C., Colombia. Teléfono: (571) 594-6175
, Jorge Echeverri2, Juan Martín Gutiérrez3
1 Médica internista, neumóloga, Hospital Universitario San Ignacio y Pontificia Universidad Javeriana, Bogotá, D.C., Colombia
2 Médico internista, nefrólogo, Hospital Universitario San Ignacio y Pontificia Universidad Javeriana, Bogotá, D.C., Colombia
3 Médico internista, reumátologo, Hospital Universitario San Ignacio y Pontificia Universidad Javeriana, Bogotá, D.C., Colombia
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Resumen

La tuberculosis constituye, en nuestro medio, una de las enfermedades infecciosas endémicas. Con el advenimiento de las nuevas terapias para el control de la artritis reumatoide, como los inhibidores del factor de necrosis tumoral, la incidencia de casos de reactivación ha aumentado notoriamente.

Se presenta el caso de una mujer de 42 años de edad, con disnea, dolor torácico, tos, derrame pleural con líquido pleural tipo exudado linfocítico, con deaminasa de adenosina (ADA) de 55 U-L e identificación de granuloma en la biopsia pleural. Se revisa la literatura y se hacen recomendaciones.

Palabras clave:
tuberculosis
antagonistas del factor de necrosis tumoral
Abstract

Tuberculosis (TB) represents one of the endemic infectious diseases in our population. The incidence of reactivate TB cases has grown notoriously with the onset of new therapeutic options for controlling rheumatoid arthritis (RA), such as tumor necrosis factor (TNF) inhibitors.

The case of a 42 year old woman is highlighted. Her condition is characterized by shortness of breath, chest pain, cough, pleural effusion, linfocitic exudate pleural fluid, ADA 55 U-L and granuloma in pleural biopsy.

A review of relevant literature and recommendations are presented.

Key words:
Tuberculosis
tumor necrosis factor antagonist
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Copyright © 2010. Asociación Colombiana de Infectología (ACIN)
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