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Vol. 14. Issue 4.
Pages 286-291 (December 2010)
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Vol. 14. Issue 4.
Pages 286-291 (December 2010)
Open Access
VIH y psoriasis en un minero de Colombia
HIV and psoriasis in a Colombian miner – Case report
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Carlos Pérez1,*, Eliana Andrea Merlo2, Lina María Murcia3, Nelcy Teresa Guerra3, Silvana Orozco3, Christian Flórez4
1 Jefe de Infectología, Hospital Universitario la Samaritana, Universidad de la Sabana, Bogotá, D.C., Colombia
2 Residente de Dermatología, Universidad El Bosque, Bogotá, D. C., Colombia
3 Residente de Medicina Interna, Universidad de la Sabana, Bogotá, D.C., Colombia
4 Residente de Medicina Interna, Universidad Militar Nueva Granada, Bogotá, D.C., Colombia
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Resumen

La incidencia de psoriasis en la población general se encuentra alrededor de 1% a 2%, similar a la encontrada en pacientes con virus de la inmunodeficiencia humana (VIH) en quienes, a pesar de cursar con una respuesta Th1 disminuida, se presenta con mayor intensidad y es más resistente a los tratamientos convencionales.

Presentamos el caso de un paciente con VIH y lesiones cutáneas extensas que comprometían la mayor parte de la superficie corporal. Después de recibir tratamiento con metotrexato, iniciado por el compromiso cutáneo, se evidenció resolución de las lesiones.

Debe tenerse en cuenta que la presentación de enfermedades cutáneas varía en estados de inmunosupresión y, asimismo, el manejo que se proponga debe ser aquél que no empeore su estado y que no interactúe con la terapia antirretroviral.

Palabras clave:
psoriasis
virus de la inmunodeficiencia humana
inmunosupresión
Abstract

The incidence of psoriasis in general population ranges from 1 to 2%, similar to that found in patients with HIV, who despite having a diminished Th1 response, are affected by a more severe form of the psoriatic disease and more refractory to conventional treatments.

We present the case of a patient with HIV and severe skin lesions, compromising most of the body surface. After receiving a methotrexate therapy, started due the extensive cutaneous involvement, an improvement of the lesions was evidenced. It should be noted that the presentation of skin diseases varies in the different states of immunosuppression, and likewise, the proposed treatment must be the one that does not worsen their condition and does not interact with antiretroviral drugs.

Key words:
Psoriasis
Human Immunodeficiency Virus
immunosuppression
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Copyright © 2010. Asociación Colombiana de Infectología (ACIN)
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