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Poikiloderma-like lesions in chest and oedema were evident on examination, as well as bilateral palpebral erythema (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). Skin biopsy showed epidermal atrophy and interface dermatitis, consistent with dermatomyositis. Additionally, a myopathic pattern was evident on the electromyogram and signs of myositis were observed in a deltoid muscle biopsy. Lab tests showed the following results: CK 2.235<span class="elsevierStyleHsp" style=""></span>UI/L, LDH 276<span class="elsevierStyleHsp" style=""></span>UI/l and GOT 125<span class="elsevierStyleHsp" style=""></span>UI/l, as well as elevated CA-125 (97.7<span class="elsevierStyleHsp" style=""></span>UI/ml) and CA 15.3 (64.11<span class="elsevierStyleHsp" style=""></span>UI/ml) tumour markers. A left adnexal mass was observed on magnetic resonance imaging (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>), as well as bile duct infiltration and ascites. The biopsy confirmed the presence of a high grade papillary serous adenocarcinoma of ovarian origin. Dermatomyositis is an autoimmune disease that is associated with occult malignancy in 10% of cases. Besides proximal muscle weakness, it is characterized by the presence of poikiloderma-like lesions in periocular area, chest and back of the hands.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Vílchez-Márquez F, Prieto-Llamas R, Sánchez-Sánchez G. Dermatomiositis asociada a cáncer ovárico. Med Clin (Barc). 2017;148:e55.</p>" ] ] "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1275 "Ancho" => 1700 "Tamanyo" => 204770 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 602 "Ancho" => 900 "Tamanyo" => 65528 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23870206/0000014800000010/v1_201706100114/S238702061730298X/v1_201706100114/en/main.assets" "Apartado" => array:4 [ "identificador" => "51820" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in medicine" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23870206/0000014800000010/v1_201706100114/S238702061730298X/v1_201706100114/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S238702061730298X?idApp=UINPBA00004N" ]
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Vol. 148. Issue 10.
Pages e55 (May 2017)
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Vol. 148. Issue 10.
Pages e55 (May 2017)
Image in medicine
Dermatomyositis associated with ovarian cancer
Dermatomiositis asociada a cáncer ovárico
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