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She showed no systemic symptomatology, except for occasional headaches. Physical examination showed multiple pedunculated tumors, soft consistency, 1–3<span class="elsevierStyleHsp" style=""></span>cm major axis, along with about 10 café au lait spots over 2<span class="elsevierStyleHsp" style=""></span>cm diameter in her trunk (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>) She also showed 0.2–0.3<span class="elsevierStyleHsp" style=""></span>cm brown macules in her axillary folds (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>) which could be noticed by examination under Wood's lamp (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>b). Eye examination and brain MRI were normal. The largest tumors were removed, finding neurofibromas in histopathology. She was diagnosed with neurofibromatosis type 1, and during follow-up, tumors that caused more discomfort were removed. Neurofibromatosis type 1 is an autosomal dominant condition with an incidence of 1/4000 people and is characterized by the presence of neurofibromas, café au lait spots and freckles. After diagnosis, genetic counseling and follow-up are important because of the possibility of developing a neurofibrosarcoma during adulthood.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Blasco-Morente G, Garrido-Colmenero C, Pérez-López I, Arias-Santiago S. Múltiples tumores cutáneos de larga evolución. 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Journal Information
Vol. 145. Issue 7.
Pages e13 (October 2015)
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Vol. 145. Issue 7.
Pages e13 (October 2015)
Image of the week
Long-lasting multiple cutaneous tumors
Múltiples tumores cutáneos de larga evolución
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Gonzalo Blasco-Morente
, Cristina Garrido-Colmenero, Israel Pérez-López, Salvador Arias-Santiago
Corresponding author
Unidad de Gestión Clínica de Dermatología Médico Quirúrgica y Venereología, Hospital Universitario Virgen de las Nieves, Granada, Spain
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