array:23 [ "pii" => "S2387020620301911" "issn" => "23870206" "doi" => "10.1016/j.medcle.2019.06.030" "estado" => "S300" "fechaPublicacion" => "2020-06-26" "aid" => "4983" "copyright" => "Elsevier España, S.L.U.. All rights reserved" "copyrightAnyo" => "2019" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2020;154:527" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S0025775319305378" "issn" => "00257753" "doi" => "10.1016/j.medcli.2019.06.029" "estado" => "S300" "fechaPublicacion" => "2020-06-26" "aid" => "4983" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2020;154:527" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "es" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Imagen médica</span>" "titulo" => "Enfermedad de Crohn metastásica" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "527" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Metastatic Crohn's disease" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 653 "Ancho" => 1305 "Tamanyo" => 246450 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Cristina Martínez, Eduardo Corradini, Roberto Cullen, Rosemarie Bentjerodt" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Cristina" "apellidos" => "Martínez" ] 1 => array:2 [ "nombre" => "Eduardo" "apellidos" => "Corradini" ] 2 => array:2 [ "nombre" => "Roberto" "apellidos" => "Cullen" ] 3 => array:2 [ "nombre" => "Rosemarie" "apellidos" => "Bentjerodt" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2387020620301911" "doi" => "10.1016/j.medcle.2019.06.030" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020620301911?idApp=UINPBA00004N" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775319305378?idApp=UINPBA00004N" "url" => "/00257753/0000015400000012/v1_202006120627/S0025775319305378/v1_202006120627/es/main.assets" ] ] "itemAnterior" => array:18 [ "pii" => "S2387020620301947" "issn" => "23870206" "doi" => "10.1016/j.medcle.2019.06.031" "estado" => "S300" "fechaPublicacion" => "2020-06-26" "aid" => "4984" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Med Clin. 2020;154:526" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>" "titulo" => "Acute otitis media with facial nerve palsy" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "526" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Otitis media aguda con parálisis del nervio facial" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 920 "Ancho" => 905 "Tamanyo" => 120141 ] ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Kalaiarasi Raja, Satvinder Singh Bakshi" "autores" => array:2 [ 0 => array:2 [ "nombre" => "Kalaiarasi" "apellidos" => "Raja" ] 1 => array:2 [ "nombre" => "Satvinder Singh" "apellidos" => "Bakshi" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020620301947?idApp=UINPBA00004N" "url" => "/23870206/0000015400000012/v1_202006190827/S2387020620301947/v1_202006190827/en/main.assets" ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Image in medicine</span>" "titulo" => "Metastatic Crohn's disease" "tieneTextoCompleto" => true "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "527" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Cristina Martínez, Eduardo Corradini, Roberto Cullen, Rosemarie Bentjerodt" "autores" => array:4 [ 0 => array:3 [ "nombre" => "Cristina" "apellidos" => "Martínez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] 1 => array:3 [ "nombre" => "Eduardo" "apellidos" => "Corradini" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:4 [ "nombre" => "Roberto" "apellidos" => "Cullen" "email" => array:1 [ 0 => "robertocullen@gmail.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 3 => array:3 [ "nombre" => "Rosemarie" "apellidos" => "Bentjerodt" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Departamento de Dermatología, Facultad de Medicina, Universidad de Chile, Santiago de Chile, Chile" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Instituto Oncológico Fundación Arturo López Pérez (FALP), Santiago de Chile, Chile" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicio de Anatomía Patológica, Laboratorio de Histopatología Citolab, Santiago de Chile, Chile" "etiqueta" => "c" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Enfermedad de Crohn metastásica" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 653 "Ancho" => 1305 "Tamanyo" => 246450 ] ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 51-year-old woman, who presented with a 4-month progression ulcer on the external face of the left thigh, initially treated with a skin graft, without improvement. One month prior to the occurrence of the lesion, she was hospitalized for an ulcer in the perianal region that was diagnosed as anthrax, experiencing clinical improvement after receiving antibiotic treatment and drainage. The patients experienced abdominal pain and diarrhoea during the last month. A colonoscopy and an intestinal histopathology study were performed, which showed Crohn's disease.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Physical examination revealed an erythematous-violaceous plaque, ulcerated, indurated, well-defined, with yellowish crusts of approximately 30<span class="elsevierStyleHsp" style=""></span>cm (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A). The histopathological study showed dermal scarring with thickened collagen bundles, fibroblasts without atypia, mild inflammatory lymphoplasmacytic infiltrate and the presence of non-caseating granulomas (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B), findings consistent with metastatic Crohn's disease. Due to the clinical and histopathological findings, therapy with oral corticosteroids and sulfasalazine was initiated, with favourable clinical cutaneous and gastrointestinal response.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Inflammatory bowel disease is associated with extraintestinal manifestations, affecting the skin in 10-15% of cases. Metastatic Crohn's disease is a specific skin lesion, it originates from the same pathophysiological process as the gastrointestinal involvement, and has a similar histopathology, characterized by the presence of non-caseating granulomas with multinucleated giant cells, far from the bowel lesions.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Martínez C, Corradini E, Cullen R, Bentjerodt R. Enfermedad de Crohn metastásica. Med Clin (Barc). 2020;154:527.</p>" ] ] "multimedia" => array:1 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 653 "Ancho" => 1305 "Tamanyo" => 246450 ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/23870206/0000015400000012/v1_202006190827/S2387020620301911/v1_202006190827/en/main.assets" "Apartado" => array:4 [ "identificador" => "51820" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in medicine" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/23870206/0000015400000012/v1_202006190827/S2387020620301911/v1_202006190827/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2387020620301911?idApp=UINPBA00004N" ]
Journal Information
Vol. 154. Issue 12.
Pages 527 (June 2020)
Share
Download PDF
More article options
Vol. 154. Issue 12.
Pages 527 (June 2020)
Image in medicine
Metastatic Crohn's disease
Enfermedad de Crohn metastásica
Visits
1
This item has received
Article information
These are the options to access the full texts of the publication Medicina Clínica (English Edition)
Subscriber
Subscribe
Purchase
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail