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The physical examination revealed a deep ulcer with a violescent raised edge and bridges of healthy epithelium crossing the base of the lesion (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>). The histopathological study revealed a mixed inflammatory infiltrate in an oedematous dermis and vascular proliferation. No atypical cells were observed. A microbiological culture of the skin was negative and blood tests proved normal. After discarding malignancy, infection or contact dermatitis, the diagnosis was peristomal pyoderma gangrenosum. Treatment was initiated with 0.1% tacrolimus ointment once a day and one dose of 0.5%<span class="elsevierStyleHsp" style=""></span>mg/kg prednisone daily, obtaining clinical improvement after one month of treatment (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>). Two months later, the patient was operated and the stoma was closed.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Miguel-Gómez L, Hermosa-Zarza E, Muñoz-Zato E, Jaén-Olasolo P. Pioderma gangrenoso periestomal asociado a cáncer de colon. 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Journal Information
Vol. 144. Issue 11.
Pages 529 (June 2015)
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Vol. 144. Issue 11.
Pages 529 (June 2015)
Image of the week
Peristomal pyoderma gangrenosum associated with colon cancer
Pioderma gangrenoso periestomal asociado a cáncer de colon
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26
Laura Miguel-Gómez
, Eva Hermosa-Zarza, Ernesto Muñoz-Zato, Pedro Jaén-Olasolo
Corresponding author
Departamento de Dermatología, Hospital Ramón y Cajal, Madrid, Spain
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