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En la exploración física destacaba un soplo sistólico en foco pulmonar. Se realizó una radiografía de tórax (<a class="elsevierStyleCrossRef" href="#fig0005">fig. 1</a>) que mostró aumento de la silueta cardíaca. La angio-TC torácica mostró una masa mediastínica de 142<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>156<span class="elsevierStyleHsp" style=""></span>×<span class="elsevierStyleHsp" style=""></span>158<span class="elsevierStyleHsp" style=""></span>mm (<a class="elsevierStyleCrossRef" href="#fig0010">figura 2</a>, flecha), deformando e infiltrando aurícula izquierda (<a class="elsevierStyleCrossRef" href="#fig0010">figura 2</a>, asterisco), produciendo leve estenosis del tronco pulmonar y de las venas pulmonares.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Se realizó biopsia con aguja gruesa que fue compatible con sarcoma sinovial con presencia de translocación del gen SYT (18q11.2). Se inició neoadyuvancia concomitante con adriamicina e ifosfamida, y radioterapia radical, con intención de valorar cirugía al final del tratamiento.</p><p id="par0015" class="elsevierStylePara elsevierViewall">El sarcoma sinovial de localización intratorácica es un tumor mesenquimatoso maligno raro, de presentación principalmente en adultos jóvenes, representando menos del 0,5% de todos los tumores pulmonares.</p><p id="par0020" class="elsevierStylePara elsevierViewall">La detección de la translocación del gen SYT (18q11.2) es muy específica para el diagnóstico de sarcoma sinovial.</p><p id="par0025" class="elsevierStylePara elsevierViewall">El tratamiento de la enfermedad localizada es la cirugía; en cambio, para los tumores localmente avanzados y metastásicos, la quimioterapia y la radioterapia son el tratamiento de elección.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:2 [ 0 => array:6 [ "identificador" => "fig0005" "etiqueta" => "Figura 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 454 "Ancho" => 950 "Tamanyo" => 29948 ] ] ] 1 => array:6 [ "identificador" => "fig0010" "etiqueta" => "Figura 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 529 "Ancho" => 800 "Tamanyo" => 48546 ] ] ] ] ] "idiomaDefecto" => "es" "url" => "/00257753/0000015800000004/v1_202202120538/S0025775321005170/v1_202202120538/es/main.assets" "Apartado" => array:4 [ "identificador" => "64289" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Imágenes médicas" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/00257753/0000015800000004/v1_202202120538/S0025775321005170/v1_202202120538/es/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S0025775321005170?idApp=UINPBA00004N" ]
Journal Information
Vol. 158. Issue 4.
Pages 198 (February 2022)
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Vol. 158. Issue 4.
Pages 198 (February 2022)
Imagen médica
Sarcoma sinovial intratorácico
Intrathoracic synovial sarcoma
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