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Rapid immunoglobulin test confirms a suspected case of COVID-19
El test rápido de inmunoglobulinas confirma un caso sospechoso de COVID-19
Judit Constán-Rodríguez
, Concepción Fernández-Roldán, Concepción López-Robles
Corresponding author
Unidad de Enfermedades Infecciosas, Hospital Universitario Virgen de las Nieves, Granada, Spain
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Before admission, he had fever and dyspnea for 5 days. He presented hypoxemic bilateral interstitial pneumonia highly suggestive for COVID 19 infection, although 3 samples (two nasopharyngeal and one bronchial exudates) for PCR were negative. The blood test revealed lymphocytopenia and an increase in LDH, AST, ALT, C-reactive protein and <span class="elsevierStyleSmallCaps">d</span>-dimer.</p><p id="par0010" class="elsevierStylePara elsevierViewall">Getting worse that requires invasive mechanical ventilation, so that treatment with azithromycin, hydroxychloroquine, lopinavir/ritonavir was initiated.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Ten days after the respiratory symptoms the IgM and IgG rapid detection test for SARS-Cov 2 was performed, being positive for both (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>).</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">Clinical and radiological improvement were demonstrated after adding pronation and the administration of tocilizumab.</p><p id="par0025" class="elsevierStylePara elsevierViewall">Immunoglobulin detection by immunochromatography can confirm coronavirus infection when PCR is negative when have passed at least 6–10 days since the onset of symptoms.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Figure 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1084 "Ancho" => 500 "Tamanyo" => 37354 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Rapid inmunoglobulin test.</p>" ] ] ] ] "idiomaDefecto" => "en" "url" => "/00257753/0000015500000004/v1_202008110620/S002577532030258X/v1_202008110620/en/main.assets" "Apartado" => array:4 [ "identificador" => "64289" "tipo" => "SECCION" "es" => array:2 [ "titulo" => "Imágenes médicas" "idiomaDefecto" => true ] "idiomaDefecto" => "es" ] "PDF" => "https://static.elsevier.es/multimedia/00257753/0000015500000004/v1_202008110620/S002577532030258X/v1_202008110620/en/main.pdf?idApp=UINPBA00004N&text.app=https://www.elsevier.es/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S002577532030258X?idApp=UINPBA00004N" ]
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