metricas
covid
Buscar en
Medicina Clínica
Toda la web
Inicio Medicina Clínica Análisis mediante una prueba de ELISA de la respuesta de anticuerpos frente a F...
Journal Information
Vol. 115. Issue 5.
Pages 176-177 (January 2000)
Share
Share
Download PDF
More article options
Vol. 115. Issue 5.
Pages 176-177 (January 2000)
Análisis mediante una prueba de ELISA de la respuesta de anticuerpos frente a Fusobacterium nucleatum y Eikenella corrodens en sujetos con enfermedad periodontal
Analysis by Elisa of antibodies against Fusobacterium nucleatum and Eikenella corrodens in individuals with periodontal disease
Visits
1788
José Gutiérrez
Corresponding author
josegf@goliat.ugr.es

Correspondencia: Camino Bajo de Huétor, 84, 1.° A. 18008 Granada.
, Rosa Guerrero, Blas Noguerol, Manuel Menéndez, José Liébana
Departamentos de Estomatología y Microbiología. Universidades de Granada y Oviedo Hospital Universitario San Cecilio. Granada.
This item has received
Article information
Fundamento

Se estudia, mediante ELISA, la síntesis de IgG, IgA e IgM frente a Fusobacterium nucleatum y Eikenella corrodens en el suero, el líquido crevicular y la saliva con sujetos con enfermedad periodontal.

Pacientes y método

Se estudiaron 26 enfermos con alta predisposición a la enfermedad y menores de 35 años, y 30 sujetos de edad comparable y con escasa predisposición a la enfermedad.

Resultados

No se encontraron diferencias para la IgG y la IgM entre los grupos, excepto para la IgM frente a E. corrodens. En el caso de la IgA se encontraron diferencias significativas cuan-do se estudiaron la saliva y el líquido crevicular para ambas bacterias, al igual que en el caso de la IgA en suero frente a E. corrodens. En todos los casos la diferencia estadística encontrada se refirió a unos valores de anticuerpos más bajos en los enfermos.

Conclusiones

La menor síntesis de IgM e IgA, fundamentalmente de esta última, frente a F. nuclearum y E. corrodens en los sujetos con enfermedad periodontal podría contribuir a la patogenia de esta enfermedad.

Palabras clave::
Anticuerpos
Fusobacterium nucleatum
Eikenella corrodens
Enfermedad periodontall.
Background

To know the synthesis of IgG, IgA, and IgM to Fusobacterium nucleatum and Eikenella corrodens in serum, crevicular liquid and saliva in subjects with periodontal disease, using ELISA test.

Patients and methods

: We studied 26 patients with high bias to the disease aged less than 35 years and 30 individuals with comparable age and with scarce bias to the disease.

Results

No differences were found for IgG and IgM titters between the groups, except for IgM to E. corrodens. For IgA, differences were found when the saliva and crevicular liquid were studied for both bacteria, as ocurred in serum IgA compared to E. corrodens. In all the cases antibody levels were lower in the patients.

Conclusions

The lower synthesis of IgM and IgA, fundamentally the latter, to F. nucleatum and E. corrodens in patients with periodontal disease would contribute to the pathogenesis of this illness.

Article

These are the options to access the full texts of the publication Medicina Clínica
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Medicina Clínica

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
E-mail
Article options
es en pt

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

Você é um profissional de saúde habilitado a prescrever ou dispensar medicamentos